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Cases of diabetes and related diabetic retinopathy (DR) have been increasing at an alarming rate in modern times. Early detection of DR is an important problem since it may cause permanent blindness in the late stages. In the last two…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Burcu Oltu , Büşra Kübra Karaca , Hamit Erdem , Atilla Özgür

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

Early detection of diabetic retinopathy (DR) is crucial as it allows for timely intervention, preventing vision loss and enabling effective management of diabetic complications. This research performs detection of DR and DME at an early…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Pranoti Nage , Sanjay Shitole

Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anca Mihai , Adrian Groza

Domain generalization for Diabetic Retinopathy (DR) classification allows a model to adeptly classify retinal images from previously unseen domains with various imaging conditions and patient demographics, thereby enhancing its…

Computer Vision and Pattern Recognition · Computer Science 2023-09-21 Sharon Chokuwa , Muhammad H. Khan

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, and most public datasets contain no clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Chenjun Li , Laurin Lux , Alexander H. Berger , Martin J. Menten , Mert R. Sabuncu , Johannes C. Paetzold

Assessing the degree of disease severity in biomedical images is a task similar to standard classification but constrained by an underlying structure in the label space. Such a structure reflects the monotonic relationship between different…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Adrian Galdran , José Dolz , Hadi Chakor , Hervé Lombaert , Ismail Ben Ayed

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, underscoring the importance of early detection for effective treatment. However, automated DR classification remains challenging due to variations in image quality, class…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Meher Boulaabi , Takwa Ben Aïcha Gader , Afef Kacem Echi , Zied Bouraoui

Diabetic retinopathy (DR) is a consequence of diabetes mellitus characterized by vascular damage within the retinal tissue. Timely detection is paramount to mitigate the risk of vision loss. However, training robust grading models is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Somayeh Pakdelmoez , Saba Omidikia , Seyyed Ali Seyyedsalehi , Seyyede Zohreh Seyyedsalehi

Diabetes is a chronic disease characterized by excess sugar in the blood and affects 422 million people worldwide, including 3.3 million in France. One of the frequent complications of diabetes is diabetic retinopathy (DR): it is the…

Convolutional Neural Networks (CNNs) have successfully been used to classify diabetic retinopathy (DR) fundus images in recent times. However, deeper representations in CNNs may capture higher-level semantics at the expense of spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Samuel Ofosu Mensah , Bubacarr Bah , Willie Brink

Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a…

Microaneurysms (MAs) are one of the earliest signs of diabetic retinopathy (DR), a frequent complication of diabetes that can lead to visual impairment and blindness. Adaptive optics scanning laser ophthalmoscopy (AOSLO) provides real-time…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Qian Zhang , Konstantina Sampani , Mengjia Xu , Shengze Cai , Yixiang Deng , He Li , Jennifer K. Sun , George Em Karniadakis

Deep learning-based models are developed to automatically detect if a retina image is `referable' in diabetic retinopathy (DR) screening. However, their classification accuracy degrades as the input images distributionally shift from their…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Jay Nandy , Wynne Hsu , Mong Li Lee

Diabetic retinopathy (DR) and age related macular degeneration (ARMD) are among the major causes of visual impairment worldwide. DR is mainly characterized by red spots, namely microaneurysms and bright lesions, specifically exudates…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Ibrahim Sadek

As a long-term complication of diabetes, diabetic retinopathy (DR) progresses slowly, potentially taking years to threaten vision. An accurate and robust evaluation of its severity is vital to ensure prompt management and care. Ordinal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Qinkai Yu , Wei Zhou , Hantao Liu , Yanyu Xu , Meng Wang , Yitian Zhao , Huazhu Fu , Xujiong Ye , Yalin Zheng , Yanda Meng

Retinopathy represents a group of retinal diseases that, if not treated timely, can cause severe visual impairments or even blindness. Many researchers have developed autonomous systems to recognize retinopathy via fundus and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Shahrukh Hashmi , Abdel Hakim Taguri , Naoufel Werghi

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression towards earlier and better patient-specific pathology management. However, conventional approaches for detecting diabetic…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Rachid Zeghlache , Pierre-Henri Conze , Mostafa El Habib Daho , Ramin Tadayoni , Pascal Massin , Béatrice Cochener , Gwenolé Quellec , Mathieu Lamard