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We propose an unsupervised method using self-clustering convolutional adversarial autoencoders to classify prostate tissue as tumor or non-tumor without any labeled training data. The clustering method is integrated into the training of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-20 Wouter Bulten , Geert Litjens

Vision foundation models (FMs) achieve state-of-the-art performance in medical imaging. However, they encode information in abstract latent representations that clinicians cannot interrogate or verify. The goal of this study is to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Philipp Wesp , Robbie Holland , Vasiliki Sideri-Lampretsa , Sergios Gatidis

To achieve reliable mining results for massive vessel trajectories, one of the most important challenges is how to efficiently compute the similarities between different vessel trajectories. The computation of vessel trajectory similarity…

Machine Learning · Computer Science 2021-06-11 Maohan Liang , Ryan Wen Liu , Shichen Li , Zhe Xiao , Xin Liu , Feng Lu

Domain shift is a problem commonly encountered when developing automated histopathology pipelines. The performance of machine learning models such as convolutional neural networks within automated histopathology pipelines is often…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Andrew Moyes , Richard Gault , Kun Zhang , Ji Ming , Danny Crookes , Jing Wang

Autoencoders are fundamental tools in classical computing for unsupervised feature extraction, dimensionality reduction, and generative learning. The Quantum Autoencoder (QAE), introduced by Romero J.[2017 Quantum Sci. Technol. 2 045001],…

Quantum Physics · Physics 2025-02-12 Li-An Lo , Li-Yi Hsu , En-Jui Kuo

Sparse autoencoders (SAEs) are a technique for sparse decomposition of neural network activations into human-interpretable features. However, current SAEs suffer from feature absorption, where specialized features capture instances of…

Machine Learning · Computer Science 2025-09-29 Anton Korznikov , Andrey Galichin , Alexey Dontsov , Oleg Rogov , Elena Tutubalina , Ivan Oseledets

We present a novel masked image modeling (MIM) approach, context autoencoder (CAE), for self-supervised representation pretraining. We pretrain an encoder by making predictions in the encoded representation space. The pretraining tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Xiaokang Chen , Mingyu Ding , Xiaodi Wang , Ying Xin , Shentong Mo , Yunhao Wang , Shumin Han , Ping Luo , Gang Zeng , Jingdong Wang

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

Genomics · Quantitative Biology 2017-11-15 Gregory P. Way , Casey S. Greene

The availability of large-scale annotated image datasets and recent advances in supervised deep learning methods enable the end-to-end derivation of representative image features that can impact a variety of image analysis problems. Such…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Euijoon Ahn , Jinman Kim , Ashnil Kumar , Michael Fulham , Dagan Feng

We demonstrate a new deep learning autoencoder network, trained by a nonnegativity constraint algorithm (NCAE), that learns features which show part-based representation of data. The learning algorithm is based on constraining negative…

Machine Learning · Computer Science 2016-01-13 Ehsan Hosseini-Asl , Jacek M. Zurada , Olfa Nasraoui

In this paper, we propose Normality-Calibrated Autoencoder (NCAE), which can boost anomaly detection performance on the contaminated datasets without any prior information or explicit abnormal samples in the training phase. The NCAE…

Machine Learning · Computer Science 2021-10-29 Jongmin Yu , Hyeontaek Oh , Minkyung Kim , Junsik Kim

Autoencoders have been widely used as a nonlinear tool for data dimensionality reduction. While autoencoders don't utilize the label information, Centroid-Encoders (CE)\cite{ghosh2022supervised} use the class label in their learning…

Machine Learning · Computer Science 2022-06-30 Tomojit Ghosh , Michael Kirby

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

Skin cancer is a crucial health issue that requires timely detection for higher survival rates. Traditional computer vision techniques face challenges in addressing the advanced variability of skin lesion features, a gap partially bridged…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Sibasish Dhibar

Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the…

Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Le Hou , Ayush Agarwal , Dimitris Samaras , Tahsin M. Kurc , Rajarsi R. Gupta , Joel H. Saltz

Unsupervised learning has been widely applied to various tasks in particle physics. However, existing models lack precise control over their learned representations, limiting physical interpretability and hindering their use for accurate…

High Energy Physics - Experiment · Physics 2025-12-01 Xing-Jian Lv , De-Xing Miao , Zi-Jun Xu , Jian-Chun Wang

Deep Learning based methods have emerged as the indisputable leaders for virtually all image restoration tasks. Especially in the domain of microscopy images, various content-aware image restoration (CARE) approaches are now used to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mangal Prakash , Alexander Krull , Florian Jug

High-impedance faults (HIF) are difficult to detect because of their low current amplitude and highly diverse characteristics. In recent years, machine learning (ML) has been gaining popularity in HIF detection because ML techniques learn…

Machine Learning · Computer Science 2021-06-28 Khushwant Rai , Farnam Hojatpanah , Firouz Badrkhani Ajaei , Katarina Grolinger