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Metabolomic based approaches have gained much attention in recent years due to their promising potential to deliver objective tools for assessment of food intake. In particular, multiple biomarkers have emerged for single foods. However,…

Methodology · Statistics 2021-05-10 Silvia D'Angelo , Lorraine Brennan , Isobel Claire Gormley

Modern biomedical studies frequently collect complex, high-dimensional physiological signals using wearables and sensors along with time-to-event outcomes, making efficient variable selection methods crucial for interpretation and improving…

Methodology · Statistics 2026-04-22 Yuanzhen Yue , Stella Self , Yichao Wu , Jiajia Zhang , Rahul Ghosal

Nonparametric varying coefficient (NVC) models are useful for modeling time-varying effects on responses that are measured repeatedly for the same subjects. When the number of covariates is moderate or large, it is desirable to perform…

Methodology · Statistics 2023-09-19 Ray Bai , Mary R. Boland , Yong Chen

Biased sampling designs can be highly efficient when studying rare (binary) or low variability (continuous) endpoints. We consider longitudinal data settings in which the probability of being sampled depends on a repeatedly measured…

Many modern time-series datasets contain large numbers of output response variables sampled for prolonged periods of time. For example, in neuroscience, the activities of 100s-1000's of neurons are recorded during behaviors and in response…

Machine Learning · Computer Science 2022-03-15 Rui Meng , Kristofer Bouchard

We study the finite sample behavior of Lasso-based inference methods such as post double Lasso and debiased Lasso. We show that these methods can exhibit substantial omitted variable biases (OVBs) due to Lasso not selecting relevant…

Statistics Theory · Mathematics 2021-09-15 Kaspar Wuthrich , Ying Zhu

Data integration methods that analyze multiple sources of data simultaneously can often provide more holistic insights than can separate inquiries of each data source. Motivated by the advantages of data integration in the era of "big…

Methodology · Statistics 2020-01-13 Yulia Baker , Tiffany M. Tang , Genevera I. Allen

In epidemiological research, causal models incorporating potential mediators along a pathway are crucial for understanding how exposures influence health outcomes. This work is motivated by integrated epidemiological and blood biomarker…

Methodology · Statistics 2024-11-28 Youngho Bae , Chanmin Kim , Fenglei Wang , Qi Sun , Kyu Ha Lee

Model selection/optimization in conformal inference is challenging, since it may break the exchangeability between labeled and unlabeled data. We study this problem in the context of conformal selection, which uses conformal p-values to…

Methodology · Statistics 2024-11-28 Tian Bai , Ying Jin

Variable selection in linear regression models has been a problem since hypothesis testing began. Which variables to include or exclude from a model is not an easy task. Techniques such as Forward, Back ward, Stepwise Regression…

Methodology · Statistics 2026-05-01 By Riyadh Alrawkan , Edward Boone , Ryad Ghanam , Anton Westveld

We present a Bayesian approach for modeling multivariate, dependent functional data. To account for the three dominant structural features in the data--functional, time dependent, and multivariate components--we extend hierarchical dynamic…

Methodology · Statistics 2019-07-02 Daniel R. Kowal , David S. Matteson , David Ruppert

Robust feature selection is vital for creating reliable and interpretable Machine Learning (ML) models. When designing statistical prediction models in cases where domain knowledge is limited and underlying interactions are unknown,…

Cellwise contamination remains a challenging problem for data scientists, particularly in research fields that require the selection of sparse features. Traditional robust methods may not be feasible nor efficient in dealing with such…

Methodology · Statistics 2024-03-04 Peng Su , Garth Tarr , Samuel Muller , Suojin Wang

Variable selection is a widely studied problem in high dimensional statistics, primarily since estimating the precise relationship between the covariates and the response is of great importance in many scientific disciplines. However, most…

Methodology · Statistics 2018-03-12 Kashif Yousuf

We propose a parsimonious extension of the classical latent class model to cluster categorical data by relaxing the class conditional independence assumption. Under this new mixture model, named Conditional Modes Model, variables are…

Methodology · Statistics 2014-02-21 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

Most of the available multivariate statistical models dictate on fitting different parameters for the covariate effects on each multiple responses. This might be unnecessary and inefficient for some cases. In this article, we propose a…

Methodology · Statistics 2013-11-04 Ozgur Asar , Ozlem Ilk

In many studies of human diseases, multiple omic datasets are measured. Typically, these omic datasets are studied one by one with the disease, thus the relationship between omics are overlooked. Modeling the joint part of multiple omics…

Methodology · Statistics 2022-09-02 Zhujie Gu , Said el Bouhaddani , Jeanine Houwing-Duistermaat , Hae-Won Uh

This paper proposes a multilevel sampling algorithm for fiber sampling problems in algebraic statistics, inspired by Henry Wynn's suggestion to adapt multilevel Monte Carlo (MLMC) ideas to discrete models. Focusing on log-linear models, we…

Computation · Statistics 2025-12-16 Nathan Kirk , Ivan Gvozdanović , Sonja Petrović

We consider the problem of identifying significant predictors in large data bases, where the response variable depends on the linear combination of explanatory variables through an unknown link function, corrupted with the noise from the…

Methodology · Statistics 2019-11-19 Wojciech Rejchel , Malgorzata Bogdan

Objectives: Metabolic Bariatric Surgery (MBS) is a critical intervention for patients living with obesity and related health issues. Accurate classification and prediction of patient outcomes are vital for optimizing treatment strategies.…