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We consider a noise driven network of integrate-and-fire neurons. The network evolves as result of the activities of the neurons following spike-timing-dependent plasticity rules. We apply a self-consistent mean-field theory to the system…

Neurons and Cognition · Quantitative Biology 2010-02-05 Chun-Chung Chen , David Jasnow

A vast majority of spiking neural networks (SNNs) are trained based on inductive biases that are not necessarily a good fit for several critical tasks that require low-latency and power efficiency. Inferring brain behavior based on the…

Neural and Evolutionary Computing · Computer Science 2023-04-20 Xi Chen , Siwei Mai , Konstantinos Michmizos

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

Statistics Theory · Mathematics 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett

Continuing advances in neural interfaces have enabled simultaneous monitoring of spiking activity from hundreds to thousands of neurons. To interpret these large-scale data, several methods have been proposed to infer latent dynamic…

Machine Learning · Computer Science 2019-08-23 Mohammad Reza Keshtkaran , Chethan Pandarinath

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

Even in the steady-state, the number of biomolecules in living cells fluctuates dynamically; and the frequency spectrum of this chemical fluctuation carries valuable information about the mechanism and the dynamics of the intracellular…

Biological Physics · Physics 2018-08-21 Sanggeun Song , Gil-Suk Yang , Seong Jun Park , Ji-Hyun Kim , Jaeyoung Sung

We present the mathematical basis of a new approach to the analysis of temporal coding. The foundation of the approach is the construction of several families of novel distances (metrics) between neuronal impulse trains. In contrast to most…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jonathan D. Victor , Keith P. Purpura

We here study a network of synaptic relations mingling excitatory and inhibitory neuron nodes that displays oscillations quite similar to electroencephalogram (EEG) brain waves, and identify abrupt variations brought about by swift synaptic…

Neurons and Cognition · Quantitative Biology 2021-02-17 Jorge Pretel , Joaquin J. Torres , J. Marro

Panel data involving longitudinal measurements of the same set of participants taken over multiple time points is common in studies to understand childhood development and disease modeling. Deep hybrid models that marry the predictive power…

Machine Learning · Computer Science 2022-03-01 Jurijs Nazarovs , Rudrasis Chakraborty , Songwong Tasneeyapant , Sathya N. Ravi , Vikas Singh

We propose a scalable semiparametric Bayesian model to capture dependencies among multiple neurons by detecting their co-firing (possibly with some lag time) patterns over time. After discretizing time so there is at most one spike at each…

Applications · Statistics 2015-06-22 Babak Shahbaba , Bo Zhou , Shiwei Lan , Hernando Ombao , David Moorman , Sam Behseta

We propose a stochastic dynamical model of noisy neural networks with complex architectures and discuss activation of neural networks by a stimulus, pacemakers and spontaneous activity. This model has a complex phase diagram with…

Disordered Systems and Neural Networks · Physics 2015-05-13 A. V. Goltsev , F. V. de Abreu , S. N. Dorogovtsev , J. F. F. Mendes

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG…

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

This paper focuses on analysis and design of time-varying complex networks having fractional order dynamics. These systems are key in modeling the complex dynamical processes arising in several natural and man made systems. Notably,…

Signal Processing · Electrical Eng. & Systems 2018-09-17 Gaurav Gupta , Sergio Pequito , Paul Bogdan

Among the versatile forms of dynamical patterns of activity exhibited by the brain, oscillations are one of the most salient and extensively studied, yet are still far from being well understood. In this paper, we provide various structural…

Systems and Control · Electrical Eng. & Systems 2021-08-12 Erfan Nozari , Robert Planas , Jorge Cortes

Functional connectivity is a fundamental property of neural networks that quantifies the segregation and integration of information between cortical areas. Due to mathematical complexity, a theory that could explain how the parameters of…

Neurons and Cognition · Quantitative Biology 2016-05-27 Diego Fasoli , Anna Cattani , Stefano Panzeri

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

The seemingly stochastic transient dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference. In vitro neurons, on the other hand, exhibit a highly deterministic…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Cultures of neurons grown on multi-electrode arrays have become a common experimental preparation for investigating developing neural networks. Experiment and simulation have shown that these developing networks eventually exhibit bursting…

Neurons and Cognition · Quantitative Biology 2026-02-27 Michael Stiber , Natalie Gonzales , Jewel YunHsuan Lee