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Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

Quantitative Methods · Quantitative Biology 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

Systems and Control · Computer Science 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

Neurons and Cognition · Quantitative Biology 2013-02-18 Vesna Vuksanović , Philipp Hövel

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is increasingly utilized for the investigation of the brain's physiological and…

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

Neurons and Cognition · Quantitative Biology 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 William Consagra , Eardi Lila

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

Machine Learning · Computer Science 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

Neurons and Cognition · Quantitative Biology 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

Applications · Statistics 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

A great improvement to the insight on brain function that we can get from fMRI data can come from effective connectivity analysis, in which the flow of information between even remote brain regions is inferred by the parameters of a…

Neurons and Cognition · Quantitative Biology 2012-08-21 G. Wu , W. Liao , S. Stramaglia , J. Ding , H. Chen , D. Marinazzo

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Understanding the neurobiology of opioid use disorder (OUD) using resting-state functional magnetic resonance imaging (rs-fMRI) may help inform treatment strategies to improve patient outcomes. Recent literature suggests time-frequency…

Neurons and Cognition · Quantitative Biology 2025-03-12 Ahmed Temtam , Megan A. Witherow , Liangsuo Ma , M. Shibly Sadique , F. Gerard Moeller , Khan M. Iftekharuddin

The estimation of causal network architectures in the brain is fundamental for understanding cognitive information processes. However, access to the dynamic processes underlying cognition is limited to indirect measurements of the hidden…

Neurons and Cognition · Quantitative Biology 2020-08-17 H. C. Ruiz-Euler , H. J. Kappen

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

Social and Information Networks · Computer Science 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa
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