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Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

Methodology · Statistics 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

We introduce a novel longitudinal mixed model for analyzing complex multidimensional functional data, addressing challenges such as high-resolution, structural complexities, and computational demands. Our approach integrates dimension…

Methodology · Statistics 2026-02-16 Arkaprava Roy , Abhra Sarkar

Accurately specifying covariance structures is critical for valid inference in longitudinal and functional data analysis, particularly when data are sparsely observed. In this study, we develop a global goodness-of-fit test to assess…

Methodology · Statistics 2025-03-31 Dhrubajyoti Ghosh , Zhuolin Song , Luo Xiao , Sheng Luo

We consider inference on the first principal direction of a $p$-variate elliptical distribution. We do so in challenging double asymptotic scenarios for which this direction eventually fails to be identifiable. In order to achieve…

Statistics Theory · Mathematics 2019-08-30 Davy Paindaveine , Julien Remy , Thomas Verdebout

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

A Brain Computer Interface (BCI) connects the human brain to the outside world, providing a direct communication channel. Electroencephalography (EEG) signals are commonly used in BCIs to reflect cognitive patterns related to motor function…

Machine Learning · Computer Science 2025-11-19 Abdullah Al Shiam , Md. Khademul Islam Molla , Abu Saleh Musa Miah , Md. Abdus Samad Kamal

Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…

Neurons and Cognition · Quantitative Biology 2022-11-28 Qiang Li , Greg Ver Steeg , Shujian Yu , Jesus Malo

While there has been much recent progress using deep learning techniques to separate speech and music audio signals, these systems typically require large collections of isolated sources during the training process. When extending audio…

Sound · Computer Science 2020-09-01 Fatemeh Pishdadian , Gordon Wichern , Jonathan Le Roux

The matrix-variate normal distribution is a popular model for high-dimensional transposable data because it decomposes the dependence structure of the random matrix into the Kronecker product of two covariance matrices: one for each of the…

Methodology · Statistics 2014-11-11 Anestis Touloumis , John Marioni , Simon Tavaré

Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the…

Methodology · Statistics 2019-10-30 Lingge Li , Dustin Pluta , Babak Shahbaba , Norbert Fortin , Hernando Ombao , Pierre Baldi

The notion of weak measurement provides a formalism for extracting information from a quantum system in the limit of vanishing disturbance to its state. Here we extend this formalism to the measurement of sequences of observables. When…

Quantum Physics · Physics 2009-11-13 Graeme Mitchison , Richard Jozsa , Sandu Popescu

Multiple comparisons in hypothesis testing often encounter structural constraints in various applications. For instance, in structural Magnetic Resonance Imaging for Alzheimer's Disease, the focus extends beyond examining atrophic brain…

Methodology · Statistics 2023-11-08 Yang Cao , Xinwei Sun , Yuan Yao

This paper discusses estimation and limited information goodness-of-fit test statistics in factor models for binary data using pairwise likelihood estimation and sampling weights. The paper extends the applicability of pairwise likelihood…

Methodology · Statistics 2026-03-30 Haziq Jamil , Irini Moustaki , Chris Skinner

Analysis of structural and functional connectivity (FC) of human brains is of pivotal importance for diagnosis of cognitive ability. The Human Connectome Project (HCP) provides an excellent source of neural data across different regions of…

Applications · Statistics 2020-07-10 Satwik Acharyya , Zhengwu Zhang , Anirban Bhattacharya , Debdeep Pati

Current functional Magnetic Resonance Imaging technology is able to resolve billions of individual functional connections characterizing the human connectome. Classical statistical inferential procedures attempting to make valid inferences…

Quantitative Methods · Quantitative Biology 2023-01-11 Alfonso Nieto-Castanon

Functional magnetic resonance imaging (fMRI) is used to extract {\em functional networks} connecting correlated human brain sites. Analysis of the resulting networks in different tasks shows that: (a) the distribution of functional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Victor M. Eguiluz , Dante R. Chialvo , Guillermo A. Cecchi , Marwan Baliki , A. Vania Apkarian

In this paper, we study the MUltiple SIgnal Classification (MUSIC) algorithm often used to image small targets when multiple measurement vectors are available. We show that this algorithm may be used when the imaging problem can be cast as…

Numerical Analysis · Mathematics 2019-01-23 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Weak-strong consistency learning strategies are widely employed in semi-supervised medical image segmentation to train models by leveraging limited labeled data and enforcing weak-to-strong consistency. However, existing methods primarily…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Chaowei Chen , Xiang Zhang , Honglie Guo , Shunfang Wang

Modern mobile health (mHealth) assessment combines self-reported measures of participants' health experiences with passively collected health behavior data throughout the day. These data are collected across multiple measurement scales,…

Methodology · Statistics 2026-03-13 Debangan Dey , Rahul Ghosal , Kathleen Merikangas , Vadim Zipunnikov

We introduce a notion of weak convergence in arbitrary metric spaces. Metric functionals are key in our analysis: weak convergence of sequences in a given metric space is tested against all the metric functionals defined on said space. When…

Functional Analysis · Mathematics 2025-06-05 Armando W. Gutiérrez , Olavi Nevanlinna
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