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Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

Quantitative Methods · Quantitative Biology 2007-05-23 Leah R. Johnson

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

Biological Physics · Physics 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu

Many bacteria rely on active cell appendages, such as type IV pili, to move over substrates and interact with neighboring cells. Here, we study the motion of individual cells and bacterial colonies, mediated by the collective interactions…

Biological Physics · Physics 2019-05-01 Wolfram Pönisch , Christoph A. Weber , Vasily Zaburdaev

We propose a general parametrizable model to capture the dynamic interaction among bacteria in the formation of micro-colonies. micro-colonies represent the first social step towards the formation of structured multicellular communities…

Populations and Evolution · Quantitative Biology 2014-10-30 Luca Canzian , Kun Zhao , Gerard C. L. Wong , Mihaela van der Schaar

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

Colonies of bacteria endowed with a pili-based self-propulsion machinery are ideal models for investigating the structure and dynamics of active many-particle systems. We study Neisseria gonorrhoeae colonies with a molecular-dynamics-based…

Soft Condensed Matter · Physics 2022-10-18 Kai Zhou , Marc Hennes , Berenike Maier , Gerhard Gompper , Benedikt Sabass

The transition from monolayers to multilayered structures in bacterial colonies is a fundamental step in biofilm development. Observed across different morphotypes and species, this transition is triggered within freely growing bacterial…

Soft Condensed Matter · Physics 2021-03-16 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Bacteria build multicellular communities termed biofilms, which are often encased in a self-secreted extracellular matrix that gives the community mechanical strength and protection against harsh chemicals. How bacteria assemble distinct…

Biological Physics · Physics 2023-09-27 Jakub A. Kochanowski , Bobby Carroll , Merrill E. Asp , Emma Kaputa , Alison E. Patteson

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Bacterial colonies are abundant on living and nonliving surfaces and are known to mediate a broad range of processes in ecology, medicine, and industry. Although extensively researched, from single cells to demographic scales, a…

Soft Condensed Matter · Physics 2018-09-14 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Bacteria are prolific at colonizing diverse surfaces under a widerange of environmental conditions, and exhibit fascinating examples of self-organization across scales. Though it has recently attracted considerable interest, the role of…

Soft Condensed Matter · Physics 2024-03-25 M. T. Khan , J. Cammann , A. Sengupta , E. Renzi , M. G. Mazza

Many organisms form colonies for a transient period of time to withstand environmental pressure. Bacterial biofilms are a prototypical example of such behavior. Despite significant interest across disciplines, physical mechanisms governing…

Soft Condensed Matter · Physics 2015-09-30 Christoph Weber , Yen Ting Lin , Nicolas Biais , Vasily Zaburdaev

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

A human pathogen, \textit{Neisseria gonorrhoeae} (NG), moves on surfaces by attaching and retracting polymeric structures called Type IV pili. The \textit{tug-of-war} between the pili results in a two-dimensional stochastic motion called…

Biological Physics · Physics 2017-11-29 Konark Bisht , Stefan Klumpp , Varsha Banerjee , Rahul Marathe

Bacterial cellulose biofilms are complex networks of strong interwoven nanofibers that control transport and protect bacterial colonies in the film. Design of diverse applications of bacterial cellulose films also relies on understanding…

Soft Condensed Matter · Physics 2022-06-09 Firoozeh Babayekhorasani , Maryam Hosseini , Patrick T. Spicer

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…

We study the clustering of a model cyanobacterium \textit{Synechocystis} into microcolonies. The bacteria are allowed to diffuse onto surfaces of different hardness, and interact with the others by aggregation and detachment. We find that…

Biological Physics · Physics 2020-03-04 Thomas Vourc'h , Julien Léopoldès , Hassan Peerhossaini

Bacteria can adjust the structure of colonies and biofilms to enhance their survival rate under external stress. Here, we explore the link between bacterial interaction forces and colony structure. We show that the activity of extracellular…

Bacteria can spontaneously develop collective motions by aligning their motions in dense systems. Here, we show that bacteria can also respond collectively to an alternating electrical field and form dynamic clusters oscillating at the same…

Soft Condensed Matter · Physics 2022-10-11 Mei Mei Bao , Isaiah Eze Igwe , Kang Chen , Tian Hui Zhang

Bacterial colonies growing on surfaces are shaped by mechanical stresses transmitted through the community, governed by the balance between cell growth and steric and cell-substrate interactions. Using overdamped dynamics simulations of…

Soft Condensed Matter · Physics 2026-01-14 Samaneh Rahbar , Ludger Santen , Reza Shaebani
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