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Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Adina Scheinfeld , Haotan Zhang , Shang Mu , Rudolf L. M. van Herten , Lucas Stoffl , Ali Erturk , Zhuhao Wu , Johannes C. Paetzold

Advances in 3D reconstruction using neural rendering have enabled high-quality 3D capture. However, they often fail when the input imagery is corrupted by motion blur, due to fast motion of the camera or the objects in the scene. This work…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Sai Sri Teja , Sreevidya Chintalapati , Vinayak Gupta , Mukund Varma T , Haejoon Lee , Aswin Sankaranarayanan , Kaushik Mitra

The fields of view of Extremely Large Telescopes will contain vast numbers of spatial sampling elements (spaxels) as their Adaptive Optics systems approach the diffraction limit over wide fields. Since this will exceed the detection…

Instrumentation and Methods for Astrophysics · Physics 2015-05-13 G. J. Murray , J. R. Allington-Smith

Optical phase contains key information for biomedical and astronomical imaging. However, it is often obscured by layers of heterogeneous and scattering media, which render optical phase imaging at different depths an utmost challenge.…

We present a novel three-dimensional (3D) imaging approach that combines two-dimensional spatial Fourier-domain imaging techniques with traditional radar pulse compression to recover both cross-range and down-range scene information. The…

Signal Processing · Electrical Eng. & Systems 2025-07-11 Jorge R. Colon-Berrios , Jason M. Merlo , Jeffrey A. Nanzer

Quantitative phase microscopy (QPM), a technique combining phase imaging and microscopy, enables visualization of the 3D topography in reflective samples, as well as the inner structure or refractive index distribution of transparent and…

Optics · Physics 2025-01-17 Vicente Mico , Juanjuan Zheng , Javier Garcia , Zeev Zalevsky , Peng Gao

We proposed a method to achieve superresolved optical imaging without beating the diffraction limit of light. This is achieved by magnifying the ideal optical image of the object through higher-order spatial frequency generation while…

Optics · Physics 2016-08-08 Zhixiang Li , Jianji Liu , Guoquan Zhang

Current multispectral imagers suffer from low photon efficiency and limited spectrum range. These limitations are partially due to the technological limitations from array sensors (CCD or CMOS), and also caused by separative measurement of…

Optics · Physics 2016-04-25 Liheng Bian , Jinli Suo , Guohai Situ , Ziwei Li , Feng Chen , Qionghai Dai

Hyperspectral imaging has become a significant source of valuable data for astronomers over the past decades. Current instrumental and observing time constraints allow direct acquisition of multispectral images, with high spatial but low…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Claire Guilloteau , Thomas Oberlin , Olivier Berné , Nicolas Dobigeon

The emerging optical multiplexing within nanoscale shows super-capacity in encoding information by using the time-domain fingerprints from uniform nanoparticles. However, the optical diffraction limit compromises the decoding throughput and…

Optics · Physics 2022-08-09 Baolei Liu , Jiayan Liao , Yiliao Song , Jie Lu , Jiajia Zhou , Fan Wang

Based on point spread function (PSF) engineering and astigmatism due to a pair of cylindrical lenses, a novel compressed imaging mechanism is proposed to achieve single-shot incoherent 3D imaging. The speckle-like PSF of the imaging system…

Optics · Physics 2021-05-24 Qiong Gao , Weidong Qu , Ming Shao , Wei Liu , Xiangzheng Cheng

Line intensity mapping (LIM) is a promising tool to efficiently probe the three-dimensional large-scale structure by mapping the aggregate emission of a spectral line from all sources that trace the matter density field. Spectral lines from…

Cosmology and Nongalactic Astrophysics · Physics 2020-10-09 Yun-Ting Cheng , Tzu-Ching Chang , James J. Bock

Multi-plane light conversion (MPLC) has recently been developed as a versatile tool for manipulating spatial distributions of the optical field through repeated phase modulations. An MPLC Device consists of a series of phase masks separated…

Optics · Physics 2023-05-09 Yuanhang Zhang , Nicolas K. Fontaine

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

Acousto-optic devices utilize the overlap of acoustic and optical fields to facilitate photon-phonon interactions. For tightly confined optical and acoustic fields, such as the sub-wavelength scales achievable in integrated devices, this…

Optics · Physics 2021-01-21 Nathan Dostart , Miloš Popović

Diffractive optical networks unify wave optics and deep learning to all-optically compute a given machine learning or computational imaging task as the light propagates from the input to the output plane. Here, we report the design of…

Optics · Physics 2022-05-23 Deniz Mengu , Muhammed Veli , Yair Rivenson , Aydogan Ozcan

We demonstrate a reconfigurable optical filter implemented using a phase-only two-dimensional liquid crystal on silicon spatial light modulator. To achieve this we utilize two different approaches leading to two different configurations in…

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

Modern high-resolution satellite sensors collect optical imagery with ground sampling distances (GSDs) of 30-50cm, which has sparked a renewed interest in photogrammetric 3D surface reconstruction from satellite data. State-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-05-14 Mathias Rothermel , Ke Gong , Dieter Fritsch , Konrad Schindler , Norbert Haala

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

Optics · Physics 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller