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The dynamics of a loop in DNA molecules at the denaturation transition is studied by scaling arguments and numerical simulations. The autocorrelation function of the state of complementary bases (either closed or open) is calculated. The…

Statistical Mechanics · Physics 2009-11-11 A. Bar , Y. Kafri , D. Mukamel

The Peyrard-Bishop DNA model describes the molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a Hamiltonian that does not consider the helical twist or any other…

Biomolecules · Quantitative Biology 2020-07-16 Mateus Rodrigues Leal , Gerald Weber

We use a statistical mechanical model to study nonthermal denaturation of DNA in the presence of protein-mediated loops. We find that looping proteins which randomly link DNA bases located at a distance along the chain could cause a…

Soft Condensed Matter · Physics 2009-12-22 K. G. Petrosyan , Chin-Kun Hu

DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives…

Biological Physics · Physics 2026-02-10 Fabrizio Olmeda , Misha Gupta , Onurcan Bektas , Steffen Rulands

We develop a theoretical description of the topological disentanglement occurring when torus knots reach the ends of a semi-flexible polymer under tension. These include decays into simpler knots and total unknotting. The minimal number of…

Statistical Mechanics · Physics 2020-11-04 Michele Caraglio , Boris Marcone , Fulvio Baldovin , Enzo Orlandini , Attilio L. Stella

Diblock copolymers by virtue of the chemical dissimilarity between the constituting blocks exhibit microphase separation in the melt state. The phase separated melt can successfully be exploited to control the morphology of the final semi…

Soft Condensed Matter · Physics 2018-02-19 Chitrita Kundu , Nikhil S. Joshi , Ashok Kumar Dasmahapatra

We investigate the kinetics of the DNA melting transition using modified versions of the Peyrard-Dauxois-Bishop and Poland-Scheraga models that include long and short range interactions. Using Brownian dynamics and Monte Carlo simulations,…

Other Condensed Matter · Physics 2007-05-23 Aaron Santos , William Klein

Fathoming interplay between symmetry and topology of many-electron wave-functions has deepened understanding of quantum many body systems, especially after the discovery of topological insulators. Topology of electron wave-functions…

Strongly Correlated Electrons · Physics 2017-03-15 SangEun Han , Gil Young Cho , Eun-Gook Moon

A single Landau level (LL) dressed with periodic electrostatic potentials can realize a plethora of interacting topological phases where the Hall conductivity generally does not equal to the LL filling factor. Their physics can be captured…

Strongly Correlated Electrons · Physics 2026-04-07 Bo Peng , Yuzhu Wang , Bo Yang

The Tethered Particle Motion (TPM) technique informs about conformational changes of DNA molecules, e.g. upon looping or interaction with proteins, by tracking the Brownian motion of a particle probe tethered to a surface by a single DNA…

Selected theoretical developments in modeling of deposition of submicrometer size (submicron) particles on solid surfaces, with and without surface diffusion, of interest in colloid, polymer, and certain biological systems, are surveyed. We…

Materials Science · Physics 2008-10-16 Vladimir Privman

The self-assembly of DNA-coated colloids into highly-ordered structures offers great promise for advanced optical materials. However, control of disorder, defects, melting, and crystal growth is hindered by the lack of a microscopic…

Soft Condensed Matter · Physics 2022-05-18 Fan Cui , Sophie Marbach , Jeana Aojie Zheng , Miranda Holmes-Cerfon , David J. Pine

The statistical mechanics of phase transitions in dense systems of polydisperse particles presents distinctive challenges to computer simulation and analytical theory alike. The core difficulty, namely dealing correctly with particle size…

Soft Condensed Matter · Physics 2013-09-03 Nigel B. Wilding , Peter Sollich

These lectures address the dynamics of phase ordering out of equilibrium in condensed matter and in quantum field theory in cosmological settings, emphasizing their similarities and differences. In condensed matter we describe the…

High Energy Physics - Phenomenology · Physics 2007-05-23 D. Boyanovsky , H. J. de Vega , R. Holman

The thermodynamic properties of DNA circular molecules are investigated by a new path integral computational method which treats in the real space the fundamental forces stabilizing the molecule. The base pair and stacking contributions to…

Soft Condensed Matter · Physics 2014-11-11 Marco Zoli

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

The paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that…

Soft Condensed Matter · Physics 2009-11-10 D. J. Bicout , E. Kats

Ultracold quantum gases are highly controllable and, thus, capable of simulating difficult quantum many-body problems ranging from condensed matter physics to astrophysics. Although experimental realizations have so far been restricted to…

Quantum Gases · Physics 2022-02-17 Andrea Tononi , Axel Pelster , Luca Salasnich

Protein collapse can be viewed as a dynamical phase transition, during which new scales and collective variables become excited while the old ones recede and fade away. This causes formidable computational bottle-necks in approaches that…

Biological Physics · Physics 2011-11-09 Andrey Krokhotin , Martin Lundgren , Antti J. Niemi

The volume occupied by unconstrained bacterial DNA in physiological solutions exceeds 1000 times the volume of the cell. Still, it is confined to a well defined region of the cell called the nucleoid, which occupies only a fraction of the…

Biological Physics · Physics 2016-09-27 Marc Joyeux