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Optimization-based models have been used to predict cellular behavior for over 25 years. The constraints in these models are derived from genome annotations, measured macro-molecular composition of cells, and by measuring the cell's growth…

Quantitative Methods · Quantitative Biology 2019-05-21 Laurence Yang , Michael A. Saunders , Jean-Christophe Lachance , Bernhard O. Palsson , José Bento

In the aftermath of an extreme natural hazard, community residents must have access to functioning food retailers to maintain food security. Food security is dependent on supporting critical infrastructure systems, including electricity,…

Computational Engineering, Finance, and Science · Computer Science 2018-05-16 Saeed Nozhati , Yugandhar Sarkale , Bruce R. Ellingwood , Edwin K. P. Chong , Hussam Mahmoud

Nowadays hybrid evolutionary algorithms, i.e, heuristic search algorithms combining several mutation operators some of which are meant to implement stochastically a well known technique designed for the specific problem in question while…

Neural and Evolutionary Computing · Computer Science 2014-04-23 Boris Mitavskiy , Jun He

Classical deterministic optimal control problems assume full information about the controlled process. The theory of control for general partially-observable processes is powerful, but the methods are computationally expensive and typically…

Optimization and Control · Mathematics 2024-08-02 Dongping Qi , Adam Dhillon , Alexander Vladimirsky

In this article, we discuss two algorithms tailored to discrete-time deterministic finite-horizon nonlinear optimal control problems or so-called deterministic trajectory optimization problems. Both algorithms can be derived from an…

Optimization and Control · Mathematics 2024-12-10 Mohammad Mahmoudi Filabadi , Tom Lefebvre , Guillaume Crevecoeur

This paper proposes an algorithm for motion planning among dynamic agents using adaptive conformal prediction. We consider a deterministic control system and use trajectory predictors to predict the dynamic agents' future motion, which is…

Path planning in the presence of dynamic obstacles is a challenging problem due to the added time dimension in search space. In approaches that ignore the time dimension and treat dynamic obstacles as static, frequent re-planning is…

Robotics · Computer Science 2016-05-24 Anirudh Vemula , Katharina Muelling , Jean Oh

Deep learning's success has been attributed to the training of large, overparameterized models on massive amounts of data. As this trend continues, model training has become prohibitively costly, requiring access to powerful computing…

Machine Learning · Computer Science 2021-11-25 Ravi S Raju , Kyle Daruwalla , Mikko Lipasti

Path planning in a changing environment is a challenging task in robotics, as moving objects impose time-dependent constraints. Recent planning methods primarily focus on the spatial aspects, lacking the capability to directly incorporate…

Robotics · Computer Science 2024-10-29 Xi Huang , Gergely Sóti , Christoph Ledermann , Björn Hein , Torsten Kröger

Estimating and quantifying uncertainty in unknown system parameters from limited data remains a challenging inverse problem in a variety of real-world applications. While many approaches focus on estimating constant parameters, a subset of…

Methodology · Statistics 2023-05-09 Andrea Arnold

We present a heuristic algorithm for solving the problem of scheduling plans of tasks. The plans are ordered vectors of tasks, and tasks are basic operations carried out by resources. Plans are tied by temporal, precedence and resource…

Artificial Intelligence · Computer Science 2021-02-09 Davide Andrea Guastella

Reachable set computation is an important tool for analyzing control systems. Simulating a control system can show general trends, but a formal tool like reachability analysis can provide guarantees of correctness. Reachability analysis for…

Systems and Control · Electrical Eng. & Systems 2025-05-07 Chelsea Sidrane , Jana Tumova

We demonstrate a new algorithm for finding protein conformations that minimize a non-bonded energy function. The new algorithm, called the difference map, seeks to find an atomic configuration that is simultaneously in two constraint…

Biomolecules · Quantitative Biology 2007-06-13 Ivan C. Rankenburg , Veit Elser

Cultures around the world have acquired unique culinary practices reflected in traditional recipe compositions. Data-driven analysis has the potential to provide interesting insights into the structure of recipes and organizational…

Physics and Society · Physics 2018-03-13 Navjot Singh , Ganesh Bagler

Decision-making under uncertainty is a critical aspect of many practical autonomous systems due to incomplete information. Partially Observable Markov Decision Processes (POMDPs) offer a mathematically principled framework for formulating…

Artificial Intelligence · Computer Science 2025-10-28 Moran Barenboim , Vadim Indelman

This paper discusses techniques for performing efficient decision-theoretic planning. We give an overview of the DRIPS decision-theoretic refinement planning system, which uses abstraction to efficiently identify optimal plans. We present…

Artificial Intelligence · Computer Science 2013-02-21 Peter Haddawy , AnHai Doan , Richard Goodwin

With diet and nutrition apps reaching 1.4 billion users in 2022 [1], it's not surprise that popular health apps, MyFitnessPal, Noom, and Calorie Counter, are surging in popularity. However, one major setback [2] of nearly all nutrition…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Michelle Han , Junyao Chen , Zhengyuan Zhou

Real-life parallel machine scheduling problems can be characterized by: (i) limited information about the exact task duration at scheduling time, and (ii) an opportunity to reschedule the remaining tasks each time a task processing is…

Optimization and Control · Mathematics 2023-11-22 Izack Cohen , Krzysztof Postek , Shimrit Shtern

We develop a tractable and flexible approach for incorporating side information into dynamic optimization under uncertainty. The proposed framework uses predictive machine learning methods (such as $k$-nearest neighbors, kernel regression,…

Optimization and Control · Mathematics 2020-07-23 Dimitris Bertsimas , Christopher McCord , Bradley Sturt

A key challenge in satisficing planning is to use multiple heuristics within one heuristic search. An aggregation of multiple heuristic estimates, for example by taking the maximum, has the disadvantage that bad estimates of a single…

Artificial Intelligence · Computer Science 2021-04-13 David Speck , André Biedenkapp , Frank Hutter , Robert Mattmüller , Marius Lindauer