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An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record…

Machine Learning · Statistics 2018-12-04 Andrew C. Miller , Ziad Obermeyer , David M. Blei , John P. Cunningham , Sendhil Mullainathan

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

Signal Processing · Electrical Eng. & Systems 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani

Mathematical models of cardiac electrical activity are one of the most important tools for elucidating information about the heart diagnostic. Even though it is one of the major problems in biomedical research, an efficient mathematical…

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

This work addresses the inverse problem of electrocardiography from a new perspective, by combining electrical and mechanical measurements. Our strategy relies on the defini-tion of a model of the electromechanical contraction which is…

Numerical Analysis · Mathematics 2015-03-24 Cesare Corrado , Jean-Frédéric Gerbeau , Philippe Moireau

We have advanced a point-process based framework for the regulation of heart beats by the autonomous nervous system and analyzed the model with and without feedback. The model without feedback was found amenable to several analytical…

Quantitative Methods · Quantitative Biology 2019-04-18 Bosco Emmanuel

This article proposes a dynamical system modeling approach for the analysis of longitudinal data of self-regulated systems experiencing multiple excitations. The aim of such an approach is to focus on the evolution of a signal (e.g., heart…

Electrocardiogram (ECG) is a widely used tool for assessing cardiac function due to its low cost and accessibility. Emergent research shows that ECGs can help make predictions on key outcomes traditionally derived from more complex…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Chris McIntosh

While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Indeed, as atria are characterized by a complex physiology…

Virtual heart models have been proposed to enhance the safety of implantable cardiac devices through closed loop validation. To communicate with a virtual heart, devices have been driven by cardiac signals at specific sites. As a result,…

Systems and Control · Computer Science 2017-03-06 Weiwei Ai , Nitish Patel , Partha Roop , Avinash Malik , Nathan Allen , Mark L. Trew

In this work we present a new idea to develop a method to separate stochastic and deterministic information contained in an electrocardiogram, ECG, which may provide new sources of information with diagnostic purposes. We assume that the…

Data Analysis, Statistics and Probability · Physics 2016-08-16 R. M. Gutiérrez , L. Sandoval

We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated…

Signal Processing · Electrical Eng. & Systems 2020-02-04 V. V. Kuznetsov , V. A. Moskalenko , N. Yu. Zolotykh

This paper presents a nonlinear reaction-diffusion-fluid system that simulates radiofrequency ablation within cardiac tissue. The model conveys the dynamic evolution of temperature and electric potential in both the fluid and solid regions,…

Numerical Analysis · Mathematics 2024-05-03 Mostafa Bendahmane , Youssef Ouakrim , Yassine Ouzrour , Mohamed Zagour

We present a novel approach to learn the formulae characterising the emergent behaviour of a dynamical system from system observations. At a high level, the approach starts by devising a statistical dynamical model of the system which…

Logic in Computer Science · Computer Science 2013-12-31 Ezio Bartocci , Luca Bortolussi , Guido Sanguinetti

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…

Optimization and Control · Mathematics 2021-02-03 Thomas Grandits , Simone Pezzuto , Jolijn M. Lubrecht , Thomas Pock , Gernot Plank , Rolf Krause

Models of electrical excitation and recovery in the heart have become increasingly detailed, but have yet to be used routinely in the clinical setting to guide personalized intervention in patients. One of the main challenges is calibrating…

We consider the monodomain model, a system of a parabolic semilinear reaction-diffusion equation coupled with a nonlinear ordinary differential equation, arising from the (simplified) mathematical description of the electrical activity of…

Numerical Analysis · Mathematics 2024-12-20 Luca Ratti , Marco Verani

The heart is a vital organ that relies on the orchestrated propagation of electrical stimuli to coordinate each heart beat. Abnormalities in the heart's electrical behaviour can be managed with a cardiac pacemaker. Recently, the closed-loop…

Systems and Control · Computer Science 2016-03-21 Eugene Yip , Sidharta Andalam , Partha S. Roop , Avinash Malik , Mark Trew , Weiwei Ai , Nitish Patel

Cardiac muscle cells can exhibit complex patterns including irregular behaviour such as chaos or (chaotic) early afterdepolarisations (EADs), which can lead to sudden cardiac death. Suitable mathematical models and their analysis help to…

Dynamical Systems · Mathematics 2021-01-15 André H. Erhardt , Susanne Solem

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi
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