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Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…

Biological Physics · Physics 2019-09-25 Rahul Vaippully , Vaibavi Ramanujan , Saumendra Bajpai , Basudev Roy

Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…

Optical tweezers are a powerful tool for the precise positioning of a variety of small objects, including single neutral atoms. Once trapped, atoms can be cooled to the motional ground state of the tweezers. For a more advanced control of…

Optical computing offers potential for ultra high-speed and low latency computation by leveraging the intrinsic properties of light. Here, we explore the use of highly nonlinear optical fibers (HNLFs) as platforms for optical computing…

The first part of this paper proposed a family of penalized convex relaxations for solving optimization problems with bilinear matrix inequality (BMI) constraints. In this part, we generalize our approach to a sequential scheme which starts…

Optimization and Control · Mathematics 2018-09-27 Mohsen Kheirandishfard , Fariba Zohrizadeh , Muhammad Adil , Ramtin Madani

Precise control of particle positioning is desirable in many optical propulsion and sorting applications. Here, we develop an integrated platform for particle manipulation consisting of a combined optical nanofiber and optical tweezers…

We introduce an interpolation framework for H-infinity model reduction founded on ideas originating in optimal-H2 interpolatory model reduction, realization theory, and complex Chebyshev approximation. By employing a Loewner "data-driven"…

Numerical Analysis · Mathematics 2013-09-03 Garret Flagg , Christopher Beattie , Serkan Gugercin

Mixed H2/H-infinity control balances performance and robustness by minimizing an H2 cost bound subject to an H-infinity constraint. However, classical Riccati/LMI solutions offer limited insight into the nonconvex optimization landscape and…

Optimization and Control · Mathematics 2026-03-06 Chih-Fan Pai , Yuto Watanabe , Yujie Tang , Yang Zheng

Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and can exert forces several orders of…

High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…

Fluid Dynamics · Physics 2025-11-03 Elena Erben , Ivan Saraev , Weida Liao , Fan Nan , Eric Lauga , Moritz Kreysing

In this paper, we present novel convex optimization formulations for designing full-state and output-feedback controllers with sparse actuation that achieve user-specified $\mathcal{H}_2$ and $\mathcal{H}_\infty$ performance criteria. For…

Systems and Control · Electrical Eng. & Systems 2024-09-17 Vedang M. Deshpande , Raktim Bhattacharya

Conventional robust H2/H-infinity control minimizes the worst-case performance, often leading to a conservative design driven by very rare parametric configurations. To reduce this conservatism while taking advantage of the stochastic…

Systems and Control · Electrical Eng. & Systems 2026-04-09 Ervan Kassarian , Francesco Sanfedino , Daniel Alazard , Andrea Marrazza

Soft actuators that respond to external stimuli play a fundamental role in microscale robotics, active matter, and bio-inspired systems. Among these actuators, photo-thermal hybrid microgels (HMGs) containing plasmonic nanoparticles enable…

Optics · Physics 2025-07-02 S. -H. Jung , C. Zhang , N. Stauffer , F. Scheffold , L. Isa

It has been argued [Tassieri, \textit{Soft Matter}, 2015, \textbf{11}, 5792] that linear microrheology with optical tweezers (MOT) of living systems ``\textit{is not an option}'', because of the wide gap between the observation time…

Fully internal and motional state controlled and individually manipulable polar molecules are desirable for many quantum science applications leveraging the rich state space and intrinsic interactions of molecules. While prior efforts at…

This paper proposes a novel density-based method for structural design considering restrictions of multi-axis machining processes. A new mathematical formulation based on Heaviside function is presented to transform the design field into a…

Optimization and Control · Mathematics 2021-10-05 Hao Deng , Albert C. To

H2-conic controller design seeks to minimize the closed-loop H2-norm for a nominal linear system while satisfying the Conic Sector Theorem for nonlinear stability. This problem has only been posed with limited design freedom, as opposed to…

Optimization and Control · Mathematics 2021-10-11 Ethan J. LoCicero , Leila Bridgeman

Reinforcement learning was carried out in a simulated environment to learn continuous velocity control over multiple motor axes. This was then applied to a real-world optical tweezers experiment with the objective of moving a laser-trapped…

Machine Learning · Computer Science 2020-11-11 Matthew Praeger , Yunhui Xie , James A. Grant-Jacob , Robert W. Eason , Ben Mills

For a time-limited version of the H$_2$ norm defined over a fixed time interval, we obtain a closed form expression of the gradients. After that, we use the gradients to propose a time-limited model order reduction method. The method…

Systems and Control · Electrical Eng. & Systems 2022-01-04 Kasturi Das , Srinivasan Krishnaswamy , Somanath Majhi

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

Biomolecules · Quantitative Biology 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake