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In molecular communication via diffusion (MCvD), the inter-symbol interference (ISI) is a well known severe problem that deteriorates both data rates and link reliability. ISI mainly occurs due to the slow and highly random propagation of…

Emerging Technologies · Computer Science 2016-04-19 Yae Jee Cho , H. Birkan Yilmaz , Weisi Guo , Chan-Byoung Chae

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-01-21 Adam Noel , Karen C. Cheung , Robert Schober

In this paper, we propose adding enzymes to the propagation environment of a diffusive molecular communication system as a strategy for mitigating intersymbol interference. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-10-17 Adam Noel , Karen C. Cheung , Robert Schober

Concentration modulation, whereby information is encoded in the concentration level of chemicals, is considered. One of the main challenges with such systems is the limited control the transmitter has on the concentration level at the…

Emerging Technologies · Computer Science 2015-12-01 Nariman Farsad , Andrea Goldsmith

Molecular communication (MC) offers a groundbreaking approach to communication inspired by biological signaling. It is particularly suited for environments where traditional electromagnetic methods fail, such as fluid mediums or within the…

Molecular Networks · Quantitative Biology 2025-03-18 Aravind Muraleedharan , Abhishek K. Gupta

Molecular communication suffers from severe inter-symbol interference, which makes constrained coding essential for reliable transmission. Run-length-limited ISI-mitigation codes are attractive because they select low-weight constrained…

Information Theory · Computer Science 2026-05-01 Melih Şahin , Ozgur B. Akan

Molecular communication is a new field of communication where molecules are used to transfer information. Among the proposed methods, molecular communication via diffusion (MCvD) is particularly effective. One of the main challenges in MCvD…

Emerging Technologies · Computer Science 2014-10-31 Burcu Tepekule , Ali E. Pusane , H. Birkan Yilmaz , Chan-Byoung Chae , Tuna Tugcu

A diffusion molecular channel is a channel with memory, as molecules released into the medium hit the receptors after a random delay. Coding over the diffusion channel is performed by choosing the type, intensity, or the released time of…

In molecular communication (MC), molecules are released from the transmitter to convey information. This paper considers a realistic molecule shift keying (MoSK) scenario with two species of molecule in two reservoirs, where the molecules…

Information Theory · Computer Science 2024-04-04 Dongliang Jing , Lin Lin , Andrew W. Eckford

In this paper, we apply dimensional analysis to study a diffusive molecular communication system that uses diffusing enzymes in the propagation environment to mitigate intersymbol interference. The enzymes bind to information molecules and…

Information Theory · Computer Science 2013-11-21 Adam Noel , Karen C. Cheung , Robert Schober

Channel memory and inter-symbol interference (ISI) are harmful factors in diffusion-based molecular communication (DBMC) between bionanosensors. To tackle these problems, this paper proposes a lightweight ISI-mitigating coding scheme to…

Information Theory · Computer Science 2023-05-24 Dongliang Jing , Andrew W. Eckford

In this paper, we propose a novel inter-symbol interference (ISI) mitigation scheme for molecular communication via diffusion (MCvD) systems with the optimal detection interval. Its rationale is to exploit the discarded duration (i.e., the…

Signal Processing · Electrical Eng. & Systems 2022-07-21 Xuan Chen , Fei Ji , Miaowen Wen , Yu Huang , Yuankun Tang , Andrew W. Eckford

Molecular communication via diffusion (MCvD) is considered as one of the most feasible communication paradigms for nanonetworks, especially for bio-nanonetworks which are usually in water-rich biological environments. Two effects that…

Signal Processing · Electrical Eng. & Systems 2022-04-14 Ruifeng Zheng , Lin Lin , Hao Yan

This paper presents a novel physics-based model for signal propagation in closed-loop molecular communication (MC) systems, which are particularly relevant for many envisioned biomedical applications, such as health monitoring or drug…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Lukas Brand , Fardad Vakilipoor , Sören Botsch , Timo Jakumeit , Sebastian Lotter , Robert Schober , Maximilian Schäfer

Intersymbol interference (ISI) is a major cause of degradation in the receiver performance of high-speed data communications systems. This arises mainly due to limited bandwidth available. The minimum Euclidean distance between any two…

Information Theory · Computer Science 2013-04-22 Nandana Rajatheva

This paper studies the capacity of molecular communications in fluid media, where the information is encoded in the number of transmitted molecules in a time-slot (amplitude shift keying). The propagation of molecules is governed by random…

Information Theory · Computer Science 2016-04-29 Siavash Ghavami , Raviraj Adve , Farshad Lahouti

In diffusion based molecular communication, the intersymbol interference (ISI) is an important reason for system performance degradation, which is caused by the random movement, out-of-order arrival and indistinguishability of the…

Information Theory · Computer Science 2019-01-01 Hui Li , Qingchao Li

An important challenge in design of modulation schemes for molecular communication is positivity of the transmission signal (only a positive concentration of molecules can be released in the environment). This restriction makes handling of…

Information Theory · Computer Science 2016-12-15 Reza Mosayebi , Amin Gohari , Mahtab Mirmohseni , Masoumeh Nasiri Kenari

Nano-scale molecular communication is a viable way of exchanging information between nano-machines. In this letter, a low-complexity and non-coherent signal detection technique is proposed to mitigate the inter-symbol-interference (ISI) and…

Emerging Technologies · Computer Science 2015-08-31 Bin Li , Mengwei Sun , Siyi Wang , Weisi Guo , Chenglin Zhao

There are now several works on the use of the additive inverse Gaussian noise (AIGN) model for the random transit time in molecular communication~(MC) channels. The randomness invariably causes inter-symbol interference (ISI) in MC, an…

Information Theory · Computer Science 2015-09-01 Siavash Ghavami , Raviraj Adve , Farshad Lahouti
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