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Retrosynthesis planning remains a central challenge in molecular discovery due to the vast and complex chemical reaction space. While traditional template-based methods offer tractability, they suffer from poor scalability and limited…

Machine Learning · Computer Science 2025-07-31 Nguyen Xuan-Vu , Daniel P Armstrong , Zlatko Jončev , Philippe Schwaller

Production agent frameworks (OpenAI Function Calling, Anthropic Tool Use, MCP) transmit tool schemas as JSON, a format designed for machine parsing, not for interpretation by language models. For small models (4B-14B), this protocol…

Software Engineering · Computer Science 2026-05-07 Furkan Sakizli

Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

This paper proposes a novel neural model for the understudied task of generating text from keywords. The model takes as input a set of un-ordered keywords, and part-of-speech (POS) based template instructions. This makes it ideal for…

Artificial Intelligence · Computer Science 2020-11-10 Abhijit Mishra , Md Faisal Mahbub Chowdhury , Sagar Manohar , Dan Gutfreund , Karthik Sankaranarayanan

In model-driven development (MDD) software emerges by systematically transforming abstract models to concrete source code. Ideally, performing those transformations is to a large extent the task of code generators. One approach for…

Software Engineering · Computer Science 2015-09-09 Pedram Mir Seyed Nazari , Bernhard Rumpe

Controllable Text Generation (CTG) is emerging area in the field of natural language generation (NLG). It is regarded as crucial for the development of advanced text generation technologies that better meet the specific constraints in…

Computation and Language · Computer Science 2023-08-25 Hanqing Zhang , Haolin Song , Shaoyu Li , Ming Zhou , Dawei Song

Multi-stage programming is a proven technique that provides predictable performance characteristics by controlling code generation. We propose a core semantics for Typed Template Haskell, an extension of Haskell that supports multi staged…

Programming Languages · Computer Science 2021-12-08 Matthew Pickering , Andres Löh , Nicolas Wu

Code generation aims to automatically generate code snippets of specific programming language according to natural language descriptions. The continuous advancements in deep learning, particularly pre-trained models, have empowered the code…

Software Engineering · Computer Science 2025-01-24 Zezhou Yang , Sirong Chen , Cuiyun Gao , Zhenhao Li , Xing Hu , Kui Liu , Xin Xia

Genetic programming is an evolutionary approach known for its performance in program synthesis. However, it is not yet mature enough for a practical use in real-world software development, since usually many training cases are required to…

Software Engineering · Computer Science 2023-01-23 Dominik Sobania , Martin Briesch , Philipp Röchner , Franz Rothlauf

Evaluating the performance of generative models in image synthesis is a challenging task. Although the Fr\'echet Inception Distance is a widely accepted evaluation metric, it integrates different aspects (e.g., fidelity and diversity) of…

Computer Vision and Pattern Recognition · Computer Science 2021-06-07 Ryoungwoo Jang , Minjee Kim , Da-in Eun , Kyungjin Cho , Jiyeon Seo , Namkug Kim

How to generate descriptions from structured data organized in tables? Existing approaches using neural encoder-decoder models often suffer from lacking diversity. We claim that an open set of templates is crucial for enriching the phrase…

Computation and Language · Computer Science 2020-02-14 Rong Ye , Wenxian Shi , Hao Zhou , Zhongyu Wei , Lei Li

Casting neural networks in generative frameworks is a highly sought-after endeavor these days. Contemporary methods, such as Generative Adversarial Networks, capture some of the generative capabilities, but not all. In particular, they lack…

Machine Learning · Computer Science 2018-03-28 Or Sharir , Ronen Tamari , Nadav Cohen , Amnon Shashua

Code generation from models is a core activity in model-driven development (MDD). For complex systems it is usually impossible to generate the entire software system from models alone. Thus, MDD requires mechanisms for integrating generated…

In recent years the field of genetic programming has made significant advances towards automatic programming. Research and development of contemporary program synthesis methods, such as PushGP and Grammar Guided Genetic Programming, can…

Programming Languages · Computer Science 2020-08-11 Edward Pantridge , Lee Spector

The motivation of the current study was to design an algorithm that can speed up the processing of a query. The important feature is generating code dynamically for a specific query. We present the technique of code generation that is…

Databases · Computer Science 2017-12-12 Xin Zhang

General program synthesis has become an important application area for genetic programming (GP), and for artificial intelligence more generally. Code Building Genetic Programming (CBGP) is a recently introduced GP method for general program…

Artificial Intelligence · Computer Science 2022-06-17 Edward Pantridge , Thomas Helmuth , Lee Spector

Open-ended text generation has become a prominent task in natural language processing due to the rise of powerful (large) language models. However, evaluating the quality of these models and the employed decoding strategies remains…

Computation and Language · Computer Science 2025-06-18 Esteban Garces Arias , Hannah Blocher , Julian Rodemann , Meimingwei Li , Christian Heumann , Matthias Aßenmacher

Compared with traditional design methods, generative design significantly attracts engineers in various disciplines. In thiswork, howto achieve the real-time generative design of optimized structures with various diversities and…

Computational Engineering, Finance, and Science · Computer Science 2024-01-23 Zongliang Du , Xinyu Ma , Wenyu Hao , Yuan Liang , Xiaoyu Zhang , Hongzhi Luo , Xu Guo

Test Driven Development (TDD) is one of the major practices of Extreme Programming for which incremental testing and refactoring trigger the code development. TDD has limited adoption in the industry, as it requires more code to be…

Software Engineering · Computer Science 2025-01-15 Moritz Mock , Jorge Melegati , Barbara Russo

Transition Matching (TM) is an emerging paradigm for generative modeling that generalizes diffusion and flow-matching models as well as continuous-state autoregressive models. TM, similar to previous paradigms, gradually transforms noise…

Machine Learning · Computer Science 2025-12-16 Uriel Singer , Yaron Lipman