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Related papers: Droplet Ripening in Concentration Gradients

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Liquid-liquid phase separation is an important mechanism for compartmentalizing the cell's cytoplasm, allowing the dynamic organization of the components necessary for survival. However, it is not clear how phase separation is affected by…

Soft Condensed Matter · Physics 2022-01-31 Estefania Vidal-Henriquez , David Zwicker

Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on passive liquid-liquid phase separation cannot capture the…

Biological Physics · Physics 2025-11-14 David Zwicker , Oliver W. Paulin , Cathelijne ter Burg

It has been proposed that during the early steps in the origin of life, small droplets could have formed via the segregation of molecules from complex mixtures by phase separation. These droplets could have provided chemical reaction…

Biological Physics · Physics 2017-04-26 David Zwicker , Rabea Seyboldt , Christoph A. Weber , Anthony A. Hyman , Frank Jülicher

Concentration gradients play a critical role in embryogenesis, bacterial locomotion, as well as the motility of active particles. Particles develop concentration profiles around them by dissolution, adsorption, or the reactivity of surface…

Droplets are essential for spatially controlling biomolecules in cells. To work properly, cells need to control the emergence and morphology of droplets. On the one hand, driven chemical reactions can affect droplets profoundly. For…

Soft Condensed Matter · Physics 2024-03-14 Noah Ziethen , David Zwicker

Absence of Ostwald ripening has been observed in living cells, which operate out of equilibrium. Using molecular dynamics we study the behaviour of liquid droplets away from equilibrium in a system of particles interacting with each other…

Biological Physics · Physics 2025-08-01 Bradley D. Keister , Saeed Najafi , Joan-Emma Shea , Krastan B. Blagoev

We study the time evolution of a sessile liquid droplet, which is initially put onto a solid surface in a non-equilibrium configuration and then evolves towards its equilibrium shape. We adapt here the standard approach to the dynamics of…

Materials Science · Physics 2007-05-23 M. J. de Ruijter , J. De Coninck , G. Oshanin

In both biological and artificial systems, concentration gradients can serve as a convenient mechanism for manipulating particles and generating motility. Particles that interact with a solute will move along its gradient; if they…

Soft Condensed Matter · Physics 2011-07-21 Gareth P. Alexander , Andrea J. Liu

We propose coupled evolution equations for the thickness of a liquid film and the density of an adsorbate layer on a partially wetting solid substrate. Therein, running droplets are studied assuming a chemical reaction underneath the…

Soft Condensed Matter · Physics 2007-05-23 Uwe Thiele , Karin John , Markus Bär

Chemically active droplets provide simple models for cell-like systems that can grow and divide. Such active droplet systems are driven away from thermodynamic equilibrium and turn over chemically, which corresponds to a simple metabolism.…

Biological Physics · Physics 2022-09-28 Jonathan Bauermann , Christoph A. Weber , Frank Jülicher

Phase separation in passive systems leads to uncontrolled droplet growth, limiting structural control in soft materials and cells. We identify a generic mechanism to arrest coarsening based on chemical interconversion between molecular…

Soft Condensed Matter · Physics 2026-03-19 Florian Raßhofer , Erwin Frey

Biological cells use droplets to separate components and spatially control their interior. Experiments demonstrate that the complex, crowded cellular environment affects the droplet arrangement and their sizes. To understand this behavior,…

Soft Condensed Matter · Physics 2021-10-27 Estefania Vidal-Henriquez , David Zwicker

Here, we study the coalescence of two droplets that are moving in the same direction on a soft surface; the motion of the droplets is caused by a gradient in the surface stiffness. As reference, stationary coalescence of the same droplets…

Soft Condensed Matter · Physics 2026-05-19 Divyansh Tripathi , Vimal Kishore , Panagiotis E. Theodorakis , Swarn Lata Singh

This study employs molecular dynamics simulations to investigate droplet dynamics when a stationary droplet on a solid surface is struck by another droplet of similar size from above. The focus is on the jumping behavior of the merged…

Fluid Dynamics · Physics 2026-03-25 Ertiza Hossain Shopnil , Jahid Emon , Md Nadeem Azad , AKM Monjur Morshed

We numerically study the coalescence dynamics of two sessile droplets with radii $R_0$. The droplets are placed on top of a rigid substrate with a contact angle of $\theta_{eq.} = \pi/9$. Having a highly wettable substrate ($\theta_{eq} \ll…

Fluid Dynamics · Physics 2022-08-22 Stefan Zitz , Tilman Richter , Konstantinos Missios , Johan Roenby

Biomolecules, such as proteins and RNAs, can phase separate in the cytoplasm of cells to form biomolecular condensates. Such condensates are liquid-like droplets that can wet biological surfaces such as membranes. Many molecules that…

Soft Condensed Matter · Physics 2024-09-04 Xueping Zhao , Susanne Liese , Alf Honigmann , Frank Jülicher , Christoph A. Weber

Results for the kinetics of vapor-liquid transitions, following temperature quenches with different densities, are presented from the molecular dynamics simulations of a Lennard-Jones system. For critical density, bicontinuous liquid and…

Statistical Mechanics · Physics 2018-03-09 Sutapa Roy , Subir K. Das

Droplet deformations caused by substrate vibrations are ubiquitous in nature and highly relevant for applications such as microreactors and single-cell sorting. The vibrations can induce droplet oscillations, a fundamental process that…

We study theoretically the self-propulsion dynamics of a small droplet on general curved surfaces by a variational approach. A new reduced model is derived based on careful computations for the capillary energy and the viscous dissipation…

Fluid Dynamics · Physics 2021-08-25 Yujuan Chen , Xianmin Xu

The phase separation mechanism of a binary liquid mixture off-critically quenched in its miscibility gap is nucleation and growth, its homogeneous phase reaching a metastable equilibrium state. The successive stages of growth of the…

Statistical Mechanics · Physics 2009-11-18 Jean Colombani , Jacques Bert
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