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Precise segmentation and anatomical identification of the vertebrae provides the basis for automatic analysis of the spine, such as detection of vertebral compression fractures or other abnormalities. Most dedicated spine CT and MR scans as…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Nikolas Lessmann , Bram van Ginneken , Pim A. de Jong , Ivana Išgum

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Motivation: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a 3D tissue volume. A 3D analysis, however, requires…

Joint analysis of multiple biomarker images and tissue morphology is important for disease diagnosis, treatment planning and drug development. It requires cross-staining comparison among Whole Slide Images (WSIs) of immuno-histochemical and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Abubakr Shafique , Morteza Babaie , Mahjabin Sajadi , Adrian Batten , Soma Skdar , H. R. Tizhoosh

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

Histopathology slides are routinely marked by pathologists using permanent ink markers that should not be removed as they form part of the medical record. Often tumour regions are marked up for the purpose of highlighting features or other…

Computer Vision and Pattern Recognition · Computer Science 2019-05-14 Sharib Ali , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Lesion segmentation from the surrounding skin is the first task for developing automatic Computer-Aided Diagnosis of skin cancer. Variant features of lesion like uneven distribution of color, irregular shape, border and texture make this…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Md. Kamrul Hasan , Basel Alyafi , Fakrul Islam Tushar

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

This paper presents a method for automatic segmentation, localization, and identification of vertebrae in arbitrary 3D CT images. Many previous works do not perform the three tasks simultaneously even though requiring a priori knowledge of…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Naoto Masuzawa , Yoshiro Kitamura , Keigo Nakamura , Satoshi Iizuka , Edgar Simo-Serra

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

In the last decade, deep learning has contributed to advances in a wide range computer vision tasks including texture analysis. This paper explores a new approach for texture segmentation using deep convolutional neural networks, sharing…

Computer Vision and Pattern Recognition · Computer Science 2017-03-16 Vincent Andrearczyk , Paul F. Whelan

Variability in staining protocols, such as different slide preparation techniques, chemicals, and scanner configurations, can result in a diverse set of whole slide images (WSIs). This distribution shift can negatively impact the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Kudaibergen Abutalip , Numan Saeed , Mustaqeem Khan , Abdulmotaleb El Saddik

While challenging, the dense segmentation of histology images is a necessary first step to assess changes in tissue architecture and cellular morphology. Although specific convolutional neural network architectures have been applied with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Korsuk Sirinukunwattana , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Digital histopathology slides are scanned and viewed under different magnifications and stored as images at different resolutions. Convolutional Neural Networks (CNNs) trained on such images at a given scale fail to generalise to those at…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Yilong Yang , Srinandan Dasmahapatra , Sasan Mahmoodi

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai