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Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Images remain the largest data source in the field of healthcare. But at the same time, they are the most difficult to analyze. More than often, these images are analyzed by human experts such as pathologists and physicians. But due to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Dikshant Sagar

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zahid Ullah , Dragan Pamucar , Jihie Kim

Hashing methods have been recently found very effective in retrieval of remote sensing (RS) images due to their computational efficiency and fast search speed. The traditional hashing methods in RS usually exploit hand-crafted features to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-07 Subhankar Roy , Enver Sangineto , Begüm Demir , Nicu Sebe

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu

Fine-grained classification of microscopic image data with limited samples is an open problem in computer vision and biomedical imaging. Deep learning based vision systems mostly deal with high number of low-resolution images, whereas…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Mengran Fan , Tapabrata Chakrabort , Eric I-Chao Chang , Yan Xu , Jens Rittscher

Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Eva Pachetti , Sotirios A. Tsaftaris , Sara Colantonio

Deep-networks-based hashing has become a leading approach for large-scale image retrieval, which learns a similarity-preserving network to map similar images to nearby hash codes. The pairwise and triplet losses are two widely used…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Shaoying Wang , Haijiang Lai , Yifan Yang , Jian Yin

Mapping X-ray images, radiology reports, and other medical data as binary codes in the common space, which can assist clinicians to retrieve pathology-related data from heterogeneous modalities (i.e., hashing-based cross-modal medical data…

Machine Learning · Computer Science 2022-05-18 Yufeng Shi , Shuhuang Chen , Xinge You , Qinmu Peng , Weihua Ou , Yue Zhao

Image retrieval with hybrid-modality queries, also known as composing text and image for image retrieval (CTI-IR), is a retrieval task where the search intention is expressed in a more complex query format, involving both vision and text…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Yida Zhao , Yuqing Song , Qin Jin

In the present study, we propose a novel case-based similar image retrieval (SIR) method for hematoxylin and eosin (H&E)-stained histopathological images of malignant lymphoma. When a whole slide image (WSI) is used as an input query, it is…

Compression technology is essential for efficient image transmission and storage. With the rapid advances in deep learning, images are beginning to be used for image recognition as well as for human vision. For this reason, research has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Takahiro Shindo , Taiju Watanabe , Kein Yamada , Hiroshi Watanabe

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

In this paper, we present a new multiple instance learning (MIL) method, called MIS-Boost, which learns discriminative instance prototypes by explicit instance selection in a boosting framework. Unlike previous instance selection based MIL…

Machine Learning · Computer Science 2011-09-13 Emre Akbas , Bernard Ghanem , Narendra Ahuja

Weakly supervised multiple instance learning (MIL) is a challenging task given that only bag-level labels are provided, while each bag typically contains multiple instances. This topic has been extensively studied in histopathological image…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Bodong Zhang , Hamid Manoochehri , Xiwen Li , Beatrice S. Knudsen , Tolga Tasdizen

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Due to the availability of large-scale multi-modal data (e.g., satellite images acquired by different sensors, text sentences, etc) archives, the development of cross-modal retrieval systems that can search and retrieve semantically…

Computer Vision and Pattern Recognition · Computer Science 2022-01-21 Georgii Mikriukov , Mahdyar Ravanbakhsh , Begüm Demir