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Synchronized neural spiking is associated with many cognitive functions and thus, merits study for its own sake. The analysis of neural synchronization naturally leads to the study of repetitive spiking and consequently to the analysis of…

Neurons and Cognition · Quantitative Biology 2017-07-19 Youngmin Park , Stewart Heitmann , G. Bard Ermentrout

The phase sensitivity curve or phase response curve (PRC) quantifies the oscillator's reaction to stimulation at a specific phase and is a primary characteristic of a self-sustained oscillatory unit. Knowledge of this curve yields a phase…

Adaptation and Self-Organizing Systems · Physics 2022-12-08 Rok Cestnik , Erik T. K. Mau , Michael Rosenblum

Many real oscillators are coupled to other oscillators and the coupling can affect the response of the oscillators to stimuli. We investigate phase response curves (PRCs) of coupled oscillators. The PRCs for two weakly coupled phase-locked…

Neurons and Cognition · Quantitative Biology 2009-11-13 Tae-Wook Ko , Bard Ermentrout

Regular firing neurons can be seen as oscillators. The phase-response curve (PRC) describes how such neurons will respond to small excitatory perturbations. Knowledge of the PRC is important as it is associated to the excitability type of…

Neurons and Cognition · Quantitative Biology 2010-01-05 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

At the level of individual neurons, various coding properties can be inferred from the input-output relationship of a cell. For small inputs, this relation is captured by the phase-response curve (PRC), which measures the effect of a small…

Neurons and Cognition · Quantitative Biology 2026-01-14 Janina Hesse , Susanne Schreiber

The Phase Response Curve (PRC) is a tool used in neuroscience that measures the phase shift experienced by an oscillator due to a perturbation applied at different phases of the limit cycle. In this paper we present a new approach to PRCs…

Dynamical Systems · Mathematics 2019-07-24 Alberto Pérez-Cervera , Tere M. Seara , Gemma Huguet

The describing function (DF) and phase response curve (PRC) are classical tools for the analysis of feedback oscillations and rhythmic behaviors, widely used across control engineering, biology, and neuroscience. These tools are known to…

Systems and Control · Electrical Eng. & Systems 2025-11-27 Robin Wroblowski , Rodolphe Sepulchre

The phase-response curve (PRC) is an important tool to determine the excitability type of single neurons which reveals consequences for their synchronizing properties. We review five methods to compute the PRC from both model data and…

Quantitative Methods · Quantitative Biology 2010-03-29 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

Phase response curves are important for analysis and modeling of oscillatory dynamics in various applications, particularly in neuroscience. Standard experimental technique for determining them requires isolation of the system and…

Adaptation and Self-Organizing Systems · Physics 2018-09-20 Rok Cestnik , Michael Rosenblum

The phase-resetting curve (PRC) describes the response of a neural oscillator to small perturbations in membrane potential. Its usefulness for predicting the dynamics of weakly coupled deterministic networks has been well characterized.…

Dynamical Systems · Mathematics 2015-05-13 Aushra Abouzeid , Bard Ermentrout

Cortical slow oscillations occur in the mammalian brain during deep sleep and have been shown to contribute to memory consolidation, an effect that can be enhanced by electrical stimulation. As the precise underlying working mechanisms are…

Neurons and Cognition · Quantitative Biology 2013-12-31 Arne Weigenand , Thomas Martinetz , Jens Christian Claussen

We prove that a group of injection-locked oscillators, each modelled using a nonlinear phase macromodel, responds as a single oscillator to small external perturbations. More precisely, we show that any group of injection-locked oscillators…

Chaotic Dynamics · Physics 2012-09-11 Jaijeet Roychowdhury

The "Phase Response Curve" (PRC) is a common tool used to analyze phase resetting in the natural sciences. We make the observation that the PRC with respect to a coordinate $y\in\mathbb{R}$ actually depends on the full choice of coordinates…

Quantitative Methods · Quantitative Biology 2021-11-15 Simon Wilshin , Matthew D. Kvalheim , Shai Revzen

In this paper, we introduce and systematically study, in terms of phase response curves (PRC), the effect of a dual pulse excitation on the dynamics of an autonomous oscillator. Specifically, we test the deviations from a linear summation…

Adaptation and Self-Organizing Systems · Physics 2015-06-16 Giri P. Krishnan , Maxim Bazhenov , Arkady Pikovsky

We demonstrate that the phase response curve (PRC) can be reconstructed using a weighted spike-triggered average of an injected fluctuating input. The key idea is to choose the weight to be proportional to the magnitude of the fluctuation…

Adaptation and Self-Organizing Systems · Physics 2009-05-18 Kaiichiro Ota , Masaki Nomura , Toshio Aoyagi

The phase response curve (PRC) is an important measure representing the interaction between oscillatory elements. To understand synchrony in biological systems, many research groups have sought to measure PRCs directly from biological cells…

Quantitative Methods · Quantitative Biology 2015-08-03 Kazuhiko Morinaga , Ryota Miyata , Toru Aonishi

In this letter, we propose for the first time a method of abstracting the PPV (Perturbation Projection Vector) characteristic of the up-to-date memristor-based oscillators. Inspired from biological oscillators and its characteristic named…

Emerging Technologies · Computer Science 2015-11-30 Bo Wang , Hanyu Wang , Miao Qi

We examine the effect of the phase-resetting curve (PRC) on the transfer of correlated input signals into correlated output spikes in a class of neural models receiving noisy, super-threshold stimulation. We use linear response theory to…

Neurons and Cognition · Quantitative Biology 2015-05-13 Andrea K. Barreiro , Eric Shea-Brown , Evan L. Thilo

Phase oscillators are a common starting point for the reduced description of many single neuron models that exhibit a strongly attracting limit cycle. The framework for analysing such models in response to weak perturbations is now…

Neurons and Cognition · Quantitative Biology 2013-02-05 Kyle C A Wedgwood , Kevin K Lin , Rüdiger Thul , Stephen Coombes

Perturbation theory is an important tool in the analysis of oscillators and their response to external stimuli. It is predicated on the assumption that the perturbations in question are "sufficiently weak", an assumption that is not always…

Neurons and Cognition · Quantitative Biology 2012-01-19 Kevin K. Lin , Kyle C. A. Wedgwood , Stephen Coombes , Lai-Sang Young
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