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The movement of motor particles consisting of one or several molecular motors bound to a cargo particle is studied theoretically. The particles move on patterns of immobilized filaments. Several patterns are described for which the motor…

Statistical Mechanics · Physics 2009-11-11 Stefan Klumpp , Reinhard Lipowsky

Lipid bilayer membranes are the fundamental biological barriers that permit life. The bilayer dynamics largely participates in orchestrating cellular workings and is characterized by substantial stability together with extreme plasticity…

Soft Condensed Matter · Physics 2022-12-05 Matteo Bottacchiari , Mirko Gallo , Marco Bussoletti , Carlo Massimo Casciola

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

Biological Physics · Physics 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

Active diffusiophoresis - swimming through interaction with a self-generated, neutral, solute gradient - is a paradigm for autonomous motion at the micrometer scale. We study this propulsion mechanism within a linear response theory.…

Statistical Mechanics · Physics 2015-05-30 Benedikt Sabass , Udo Seifert

Fluid membranes made out of lipid bilayers are the fundamental separation structure in eukaryotic cells. Many physiological processes rely on dramatic shape and topological changes (e.g. fusion, fission) of fluid membrane systems. Fluidity…

Numerical Analysis · Mathematics 2010-07-29 Marino Arroyo , Antonio DeSimone , Luca Heltai

Membrane organization is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is to understand the lateral heterogeneous structures in membranes and membrane fluidity in the presence of…

Soft Condensed Matter · Physics 2007-11-09 Chun-Lai Ren , Yu-qiang Ma

Via hydrodynamics preserving molecular dynamics simulations we study growth phenomena in a phase separating symmetric binary mixture model. We quench high-temperature homogeneous configurations to state points inside the miscibility gap,…

Soft Condensed Matter · Physics 2021-07-23 Koyel Das , Subir K. Das

Combining extensive molecular dynamics simulations of lipid bilayer systems of varying chemical composition with single-trajectory analyses we systematically elucidate the stochastic nature of the lipid motion. We observe subdiffusion over…

Soft Condensed Matter · Physics 2015-06-11 Jae-Hyung Jeon , Hector Martinez-Seara Monne , Matti Javanainen , Ralf Metzler

We apply a hybrid Molecular Dynamics and mesoscopic simulation technique to study the dynamics of two dimensional colloidal discs in confined geometries. We calculate the velocity autocorrelation functions, and observe the predicted…

Soft Condensed Matter · Physics 2015-05-13 Jimaan Sané , Ard A. Louis , Johan Padding

The diffusion in two dimensions of non-interacting active particles that follow an arbitrary motility pattern is considered for analysis. Accordingly, the transport equation is generalized to take into account an arbitrary distribution of…

Statistical Mechanics · Physics 2020-09-01 Francisco J. Sevilla

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to…

Depending on their mechanism of self-propulsion, active particles can exhibit a time-dependent, often periodic, propulsion velocity. The precise propulsion velocity profile determines their mean square displacement and their effective…

Soft Condensed Matter · Physics 2024-05-06 Arnau Jurado Romero , Carles Calero , Rossend Rey

The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes,…

Subcellular Processes · Quantitative Biology 2019-11-22 Thomas R. Weikl , Jinglei Hu , Batuhan Kav , Bartosz Rozycki

Membrane bending is an extensively studied problem from both modeling and experimental perspectives because of the wide implications of curvature generation in cell biology. Many of the curvature generating aspects in membranes can be…

Soft Condensed Matter · Physics 2021-07-21 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We investigate the influence of a self-propelling, out-of-equilibrium active particle on generalized elastic systems, including flexible and semiflexible polymers, fluid membranes, and fluctuating interfaces, while accounting for…

Soft Condensed Matter · Physics 2024-01-25 Alessandro Taloni

The adhesion of cells is mediated by membrane receptors that bind to complementary ligands in apposing cell membranes. It is generally assumed that the lateral diffusion of mobile receptor-ligand bonds in membrane-membrane adhesion zones is…

Soft Condensed Matter · Physics 2007-05-23 H. Krobath , G. J. Schuetz , R. Lipowsky , T. R. Weikl

We study the relaxation dynamics of a compressible bilayer vesicle with an asymmetry in the viscosity of the inner and outer fluid medium. First we explore the stability of the vesicle free energy which includes a coupling between the…

Soft Condensed Matter · Physics 2017-01-03 T. V. Sachin Krishnan , Ryuichi Okamoto , Shigeyuki Komura

The electrostatic contribution to spontaneous membrane curvature is calculated within Poisson-Boltzmann theory under a variety of assumptions and emphasizing parameters in the physiological range. Asymmetric surface charges, either fixed…

Condensed Matter · Physics 2009-10-28 Tom Chou , Marko V. Jaric' , Eric D. Siggia

An interfacial regularized Stokeslet scheme is presented to predict the motion of solid bodies (e.g. proteins or gel-phase domains) embedded within flowing lipid bilayer membranes. The approach provides a numerical route to calculate…

Biological Physics · Physics 2019-10-23 Brian A. Camley , Frank L. H. Brown

Populations of swimming microorganisms produce fluid motions that lead to dramatically enhanced diffusion of tracer particles. Using simulations of suspensions of swimming particles in a periodic domain, we capture this effect and show that…

Soft Condensed Matter · Physics 2008-07-22 Patrick T. Underhill , Juan P. Hernández-Ortiz , Michael D. Graham