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We study a multiclass multiple instance learning (MIL) problem where the labels only suggest whether any instance of a class exists or does not exist in a training sample or example. No further information, e.g., the number of instances of…

Machine Learning · Statistics 2019-03-15 Xi-Lin Li

Chest X-rays play a pivotal role in diagnosing respiratory diseases such as pneumonia, tuberculosis, and COVID-19, which are prevalent and present unique diagnostic challenges due to overlapping visual features and variability in image…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Yiming Lei , Michael Nguyen , Tzu Chia Liu , Hyounkyun Oh

Pathology detection and delineation enables the automatic interpretation of medical scans such as chest X-rays while providing a high level of explainability to support radiologists in making informed decisions. However, annotating…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Philip Müller , Felix Meissen , Johannes Brandt , Georgios Kaissis , Daniel Rueckert

Computed Tomography (CT) scans provide a detailed image of the lungs, allowing clinicians to observe the extent of damage caused by COVID-19. The CT severity score (CTSS) based scoring method is used to identify the extent of lung…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Anand Thyagachandran , Hema A Murthy

The automated Interstitial Lung Diseases (ILDs) classification technique is essential for assisting clinicians during the diagnosis process. Detecting and classifying ILDs patterns is a challenging problem. This paper introduces an…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Masum Shah Junayed , Afsana Ahsan Jeny , Md Baharul Islam , Ikhtiar Ahmed , A F M Shahen Shah

The novel coronavirus disease 2019 (COVID-19) has been spreading rapidly around the world and caused significant impact on the public health and economy. However, there is still lack of studies on effectively quantifying the lung infection…

Image and Video Processing · Electrical Eng. & Systems 2020-04-14 Xiaocong Chen , Lina Yao , Yu Zhang

During the COVID-19 pandemic, medical imaging techniques like computed tomography (CT) scans have demonstrated effectiveness in combating the rapid spread of the virus. Therefore, it is crucial to conduct research on computerized models for…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Basma Jumaa Saleh , Zaid Omar , Vikrant Bhateja , Lila Iznita Izhar

Multiple Instance Learning (MIL) is increasingly being used as a support tool within clinical settings for pathological diagnosis decisions, achieving high performance and removing the annotation burden. However, existing approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Sungrae Hong , Kyungeun Kim , Juhyeon Kim , Sol Lee , Jisu Shin , Chanjae Song , Mun Yong Yi

Recent research on COVID-19 suggests that CT imaging provides useful information to assess disease progression and assist diagnosis, in addition to help understanding the disease. There is an increasing number of studies that propose to use…

Deep learning models for COVID-19 detection from chest CT scans generally perform well when the training and test data originate from the same institution, but they often struggle when scans are drawn from multiple centres with differing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Asmita Yuki Pritha , Jason Xu , Daniel Ding , Justin Li , Aryana Hou , Xin Wang , Shu Hu

Reliable detection of out-of-distribution (OOD) inputs is increasingly understood to be a precondition for deployment of machine learning systems. This paper proposes and investigates the use of contrastive training to boost OOD detection…

Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Respiratory sound contains crucial information for the early diagnosis of fatal lung diseases. Since the COVID-19 pandemic, there has been a growing interest in contact-free medical care based on electronic stethoscopes. To this end,…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Sangmin Bae , June-Woo Kim , Won-Yang Cho , Hyerim Baek , Soyoun Son , Byungjo Lee , Changwan Ha , Kyongpil Tae , Sungnyun Kim , Se-Young Yun

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

Early detection of COVID-19 is key in containing the pandemic. Disease detection and evaluation based on imaging is fast and cheap and therefore plays an important role in COVID-19 handling. COVID-19 is easier to detect in chest CT,…

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Multiple instance learning (MIL) is a form of weakly supervised learning where training instances are arranged in sets, called bags, and a label is provided for the entire bag. This formulation is gaining interest because it naturally fits…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Marc-André Carbonneau , Veronika Cheplygina , Eric Granger , Ghyslain Gagnon

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Federated Learning is the most promising way to train robust Deep Learning models for the segmentation of Covid-19-related findings in chest CTs. By learning in a decentralized fashion, heterogeneous data can be leveraged from a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-17 Camila Gonzalez , Christian Harder , Amin Ranem , Ricarda Fischbach , Isabel Kaltenborn , Armin Dadras , Andreas Bucher , Anirban Mukhopadhyay