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Structured point process data harvested from various platforms poses new challenges to the machine learning community. By imposing a matrix structure to repeatedly observed marked point processes, we propose a novel mixture model of…
Learning latent expression themes that best express complex patterns in a sample is a central problem in data mining and scientific research. For example, in computational biology we seek a set of salient gene expression themes that explain…
We propose an efficient linear-time graph-based divisive cluster analysis approach called Reductive Clustering. The approach tries to reveal the hierarchical structural information through reducing the graph into a more concise one…
The representation of complex systems as networks is inappropriate for the study of certain problems. We show several examples of social, biological, ecological and technological systems where the use of complex networks gives very limited…
In online clustering problems, there is often a large amount of uncertainty over possible cluster assignments that cannot be resolved until more data are observed. This difficulty is compounded when clusters follow complex distributions, as…
In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…
Community detection, which focuses on clustering nodes or detecting communities in (mostly) a single network, is a problem of considerable practical interest and has received a great deal of attention in the research community. While being…
Folksonomy is said to provide a democratic tagging system that reflects the opinions of the general public, but it is not a classification system and it is hard to make sense of. It would be necessary to share a representation of contexts…
When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…
Graphs may be used to represent many different problem domains -- a concrete example is that of detecting communities in social networks, which are represented as graphs. With big data and more sophisticated applications becoming widespread…
The evaluation of the performance of clustered cooperative beamforming in cellular networks generally requires the solution of complex non-convex optimization problems. In this letter, a framework based on a hypergraph formalism is proposed…
Spectral clustering methods have gained widespread recognition for their effectiveness in clustering high-dimensional data. Among these techniques, constrained spectral clustering has emerged as a prominent approach, demonstrating enhanced…
We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…
Finding a suitable data representation for a specific task has been shown to be crucial in many applications. The success of subspace clustering depends on the assumption that the data can be separated into different subspaces. However,…
Deciphering gene regulatory networks is a central problem in computational biology. Here, we explore the use of multi-modal neural networks to learn predictive models of gene expression that include cis and trans regulatory components. We…
Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…
Constrained clustering has gained significant attention in the field of machine learning as it can leverage prior information on a growing amount of only partially labeled data. Following recent advances in deep generative models, we…
Gaussian Graphical Models (GGMs) are widely used in high-dimensional data analysis to synthesize the interaction between variables. In many applications, such as genomics or image analysis, graphical models rely on sparsity and clustering…
Graph clustering (or community detection) has long drawn enormous attention from the research on web mining and information networks. Recent literature on this topic has reached a consensus that node contents and link structures should be…
Modern network analysis often involves multi-layer network data in which the nodes are aligned, and the edges on each layer represent one of the multiple relations among the nodes. Current literature on multi-layer network data is mostly…