Related papers: Multi-scale analysis and clustering of co-expressi…
Mixture model-based frameworks are very popular for statistical inference in clustering. While convenient for producing probabilistic estimates of cluster assignments and uncertainty, they are prone to misspecification, which can lead to…
Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…
Graph clustering is a fundamental computational problem with a number of applications in algorithm design, machine learning, data mining, and analysis of social networks. Over the past decades, researchers have proposed a number of…
We propose a novel method to cluster gene networks. Based on a dissimilarity built using correlation structures, we consider networks that connect all the genes based on the strength of their dissimilarity. The large number of genes require…
Research data sets are growing to unprecedented sizes and network modeling is commonly used to extract complex relationships in diverse domains, such as genetic interactions involved in disease, logistics, and social communities. As the…
With the explosive growth of multi-source data, multi-view clustering has attracted great attention in recent years. Most existing multi-view methods operate in raw feature space and heavily depend on the quality of original feature…
In this paper, we consider sparse networks consisting of a finite number of non-overlapping communities, i.e. disjoint clusters, so that there is higher density within clusters than across clusters. Both the intra- and inter-cluster edge…
Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…
In this paper, we investigate community detection in networks in the presence of node covariates. In many instances, covariates and networks individually only give a partial view of the cluster structure. One needs to jointly infer the full…
We consider the semi-supervised clustering problem where crowdsourcing provides noisy information about the pairwise comparisons on a small subset of data, i.e., whether a sample pair is in the same cluster. We propose a new approach that…
A natural approach to analyze interaction data of form "what-connects-to-what-when" is to create a time-series (or rather a sequence) of graphs through temporal discretization (bandwidth selection) and spatial discretization (vertex…
Fair graph clustering is crucial for ensuring equitable representation and treatment of diverse communities in network analysis. Traditional methods often ignore disparities among social, economic, and demographic groups, perpetuating…
Coexpression of genes or, more generally, similarity in the expression profiles poses an unsurmountable obstacle to inferring the gene regulatory network (GRN) based solely on data from DNA microarray time series. Clustering of genes with…
Graphs have become increasingly popular in modeling structures and interactions in a wide variety of problems during the last decade. Graph-based clustering and semi-supervised classification techniques have shown impressive performance.…
To identify novel dynamic patterns of gene expression, we develop a statistical method to cluster noisy measurements of gene expression collected from multiple replicates at multiple time points, with an unknown number of clusters. We…
Microarray technology is a process that allows thousands of genes simultaneously monitor to various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively used to make proteins,…
This article explores and analyzes the unsupervised clustering of large partially observed graphs. We propose a scalable and provable randomized framework for clustering graphs generated from the stochastic block model. The clustering is…
Spectral clustering is popular among practitioners and theoreticians alike. While performance guarantees for spectral clustering are well understood, recent studies have focused on enforcing ``fairness'' in clusters, requiring them to be…
Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conventional algorithms to process large…
Spatial transcriptomics measures the expression of thousands of genes in a tissue sample while preserving its spatial structure. This class of technologies has enabled the investigation of the spatial variation of gene expressions and their…