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In the rapidly evolving domain of next generation sequencing and bioinformatics analysis, data generation is one aspect that is increasing at a concomitant rate. The burden associated with processing large amounts of sequencing data has…

Genomics · Quantitative Biology 2015-03-11 Matthew J. Wade , Thomas P. Curtis , Russell J. Davenport

The LINPACK benchmark reports the performance of a computer for solving a system of linear equations with dense random matrices. Although this task was not designed with a real application directly in mind, the LINPACK benchmark has been…

Quantum Physics · Physics 2021-07-13 Yulong Dong , Lin Lin

Network simulation is pivotal in network modeling, assisting with tasks ranging from capacity planning to performance estimation. Traditional approaches such as Discrete Event Simulation (DES) face limitations in terms of computational cost…

Networking and Internet Architecture · Computer Science 2026-03-13 Carlos Güemes-Palau , Miquel Ferriol-Galmés , Jordi Paillisse-Vilanova , Albert López-Brescó , Pere Barlet-Ros , Albert Cabellos-Aparicio

Comparing mathematical models offers a means to evaluate competing scientific theories. However, exact methods of model calibration are not applicable to many probabilistic models which simulate high-dimensional spatio-temporal data.…

Quantitative Methods · Quantitative Biology 2026-01-13 Robert A McDonald , Helen M Byrne , Heather A Harrington , Thomas Thorne , Bernadette J Stolz

Quantum computation is a promising emerging technology which, compared to conventional computation, allows for substantial speed-ups e.g. for integer factorization or database search. However, since physical realizations of quantum…

Quantum Physics · Physics 2018-06-07 Alwin Zulehner , Robert Wille

The emergence of Big Data in recent years has resulted in a growing need for efficient data processing solutions. While infrastructures with sufficient compute power are available, the I/O bottleneck remains. The Linux page cache is an…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-06 Hoang-Dung Do , Valerie Hayot-Sasson , Rafael Ferreira da Silva , Christopher Steele , Henri Casanova , Tristan Glatard

With the rapid growth of the machine learning applications, the workloads of future HPC systems are anticipated to be a mix of scientific simulation, big data analytics, and machine learning applications. Simulation is a great research…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-05 Xin Wang , Misbah Mubarak , Yao Kang , Robert B. Ross , Zhiling Lan

Many computer systems for calculating the proper organization of memory are among the most critical issues. Using a tier cache memory (along with branching prediction) is an effective means of increasing modern multi-core processors'…

Networking and Internet Architecture · Computer Science 2021-05-21 Mohamed A. Hamada , Abdelrahman Abdallah

By analyzing energy-efficient management of data centers, this paper proposes and develops a class of interesting {\it Group-Server Queues}, and establishes two representative group-server queues through loss networks and impatient…

Performance · Computer Science 2017-07-24 Quan-Lin Li , Jing-Yu Ma , Mingzhou Xie , Li Xia

To scale Gaussian processes (GPs) to large data sets we introduce the robust Bayesian Committee Machine (rBCM), a practical and scalable product-of-experts model for large-scale distributed GP regression. Unlike state-of-the-art sparse GP…

Machine Learning · Statistics 2015-05-25 Marc Peter Deisenroth , Jun Wei Ng

The time-critical industrial applications pose intense demands for enabling long-distance deterministic networks. However, previous priority-based and weight-based scheduling methods focus on probabilistically reducing average delay, which…

Networking and Internet Architecture · Computer Science 2024-09-17 Yudong Huang , Shuo Wang , Shiyin Zhu , Guoyu Peng , Xinyuan Zhang , Tao Huang , Xinmin Liu

Recently Quantum Computation has generated a lot of interest due to the discovery of a quantum algorithm which can factor large numbers in polynomial time. The usefulness of a quantum com puter is limited by the effect of errors. Simulation…

Quantum Physics · Physics 2007-05-23 Kevin M. Obenland , Alvin M. Despain

We provide algorithms for efficiently addressing quantum memory in parallel. These imply that the standard circuit model can be simulated with low overhead by the more realistic model of a distributed quantum computer. As a result, the…

Optimizing communication performance is imperative for large-scale computing because communication overheads limit the strong scalability of parallel applications. Today's network cards contain rather powerful processors optimized for data…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-20 Torsten Hoefler , Salvatore Di Girolamo , Konstantin Taranov , Ryan E. Grant , Ron Brightwell

Quantum circuit simulation is crucial for the development of quantum algorithms, particularly given the high cost and noise limitations of physical quantum hardware. While full-state quantum circuit simulation is commonly employed for…

Quantum Physics · Physics 2026-04-15 Chuan-Chi Wang , Yan-Jie Wang , Chia-Heng Tu , Shih-Hao Hung

As customized accelerator design has become increasingly popular to keep up with the demand for high performance computing, it poses challenges for modern simulator design to adapt to such a large variety of accelerators. Existing…

Programming Languages · Computer Science 2022-02-03 Zhijing Li , Yuwei Ye , Stephen Neuendorffer , Adrian Sampso

Rather than directly considering the queuing delay of data, this memo focuses on reducing the delay that congestion signals experience within a queue management algorithm, which can be greater than the delay that the data itself experiences…

Networking and Internet Architecture · Computer Science 2019-04-16 Bob Briscoe

This exposition presents nimblewomble, a software package to perform wombling, or boundary analysis, using the nimble Bayesian hierarchical modeling language in the R statistical computing environment. Wombling is used widely to track…

Computation · Statistics 2025-04-11 Aritra Halder , Sudipto Banerjee

This paper presents a new model for solving the optimal server location problem in a spatial hypercube queueing model. Unlike deterministic location models, our approach accounts for server availability, varying utilization levels, and…

Optimization and Control · Mathematics 2025-11-21 Cheng Hua , Arthur J. Swersey , Wenqian Xing , Yi Zhang

We consider the problem of providing service guarantees in a high-speed packet switch. As basic requirements, the switch should be scalable to high speeds per port, a large number of ports and a large number of traffic flows with…

Networking and Internet Architecture · Computer Science 2007-05-23 Victor Firoiu , Xiaohui Zhang , Emre Gunduzhan , Nicolas Christin