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Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Meta-learning involves training models on a variety of training tasks in a way that enables them to generalize well on new, unseen test tasks. In this work, we consider meta-learning within the framework of high-dimensional multivariate…

Statistics Theory · Mathematics 2024-04-01 Yanhao Jin , Krishnakumar Balasubramanian , Debashis Paul

Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and…

Machine Learning (ML) models have gained popularity in medical imaging analysis given their expert level performance in many medical domains. To enhance the trustworthiness, acceptance, and regulatory compliance of medical imaging models…

Human-Computer Interaction · Computer Science 2025-06-06 Mischa Dombrowski , Andrea Prenner , Bernhard Kainz

Metabolic disorders, particularly type 2 diabetes mellitus (T2DM), represent a significant global health burden, disproportionately impacting genetically predisposed populations such as the Pima Indians (a Native American tribe from south…

Machine Learning · Computer Science 2025-09-24 Iram Wajahat , Amritpal Singh , Fazel Keshtkar , Syed Ahmad Chan Bukhari

Problem Definition. Increasing costs of healthcare highlight the importance of effective disease prevention. However, decision models for allocating preventive care are lacking. Methodology/Results. In this paper, we develop a data-driven…

Machine Learning · Computer Science 2023-08-15 Mathias Kraus , Stefan Feuerriegel , Maytal Saar-Tsechansky

Alzheimer disease (AD) is a neurodegenerative disease that lacks specific treatment options. Natural drugs have displayed neuroprotective effects; however, their high-throughput discovery is challenging because of the expense of…

Other Quantitative Biology · Quantitative Biology 2026-04-28 Hafiza Syeda Yusra Tirmizi , Syed Ibad Hasnain , Muhammad Faris , Rabail Khowaja , Saad Abdullah

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

Machine Learning · Computer Science 2024-06-12 Ashwin Ram

Myocardial Infarction is a main cause of mortality globally, and accurate risk prediction is crucial for improving patient outcomes. Machine Learning techniques have shown promise in identifying high-risk patients and predicting outcomes.…

Machine Learning · Computer Science 2024-04-24 Ana Letícia Garcez Vicente , Roseval Donisete Malaquias Junior , Roseli A. F. Romero

This study presents an application of machine learning (ML) methods for detecting the presence of stenoses and aneurysms in the human arterial system. Four major forms of arterial disease -- carotid artery stenosis (CAS), subclavian artery…

Machine Learning · Computer Science 2021-08-03 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…

Machine Learning · Computer Science 2020-08-17 Maria Hügle , Gabriel Kalweit , Thomas Huegle , Joschka Boedecker

Investigation on the electrocardiogram (ECG) signals is an essential way to diagnose heart disease since the ECG process is noninvasive and easy to use. This work presents a supraventricular arrhythmia prediction model consisting of a few…

Signal Processing · Electrical Eng. & Systems 2021-12-28 Pampa Howladar , Manodipan Sahoo

Machine learning models for continuous outcomes often yield systematically biased predictions, particularly for values that largely deviate from the mean. Specifically, predictions for large-valued outcomes tend to be negatively biased…

Machine Learning · Statistics 2024-09-05 Hwiyoung Lee , Shuo Chen

Background: Overweight and obesity are an increasing phenomenon worldwide. Predicting future overweight or obesity early in the childhood reliably could enable a successful intervention by experts. While a lot of research has been done…

Machine Learning · Computer Science 2019-11-20 Ilkka Rautiainen , Sami Äyrämö

This systematic review explores the use of machine learning (ML) in predicting diabetes, focusing on datasets, algorithms, training methods, and evaluation metrics. It examines datasets like the Singapore National Diabetic Retinopathy…

Software Engineering · Computer Science 2026-04-30 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba

Clinical predictions using clinical data by computational methods are common in bioinformatics. However, clinical predictions using information from genomics datasets as well is not a frequently observed phenomenon in research. Precision…

Genomics · Quantitative Biology 2021-06-25 Moeez M. Subhani , Ashiq Anjum

Traditional computational methods, such as the finite element analysis, have provided valuable insights into uncovering the underlying mechanisms of brain physical behaviors. However, precise predictions of brain physics require effective…

Machine Learning · Computer Science 2023-10-18 Jixin Hou , Nicholas Filla , Xianyan Chen , Mir Jalil Razavi , Tianming Liu , Xianqiao Wang

Worldwide, several cases go undiagnosed due to poor healthcare support in remote areas. In this context, a centralized system is needed for effective monitoring and analysis of the medical records. A web-based patient diagnostic system is a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Harish Rajora , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

Data-driven techniques are used in cyber-physical systems (CPS) for controlling autonomous vehicles, handling demand responses for energy management, and modeling human physiology for medical devices. These data-driven techniques extract…

Machine Learning · Computer Science 2017-08-16 Sangdon Park , James Weimer , Insup Lee

One important problem in microbiome analysis is to identify the bacterial taxa that are associated with a response, where the microbiome data are summarized as the composition of the bacterial taxa at different taxonomic levels. This paper…

Applications · Statistics 2016-03-04 Pixu Shi , Anru Zhang , Hongzhe Li