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We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We consider a metapopulation model of cholera describing explicitly the movement of individuals and contaminated water between locations as well as a simple vaccination mechanism. The global stability of the disease-free equilibrium point…

Populations and Evolution · Quantitative Biology 2025-05-26 Abdramane Annour Saad , Julien Arino , Patrick M Tchepmo Djomegni , Mahamat S Daoussa Haggar

The possibility to analyze, quantify and forecast epidemic outbreaks is fundamental when devising effective disease containment strategies. Policy makers are faced with the intricate task of drafting realistically implementable policies…

Social and Information Networks · Computer Science 2015-04-07 Antonio Lima , Veljko Pejovic , Luca Rossi , Mirco Musolesi , Marta Gonzalez

Epidemics like Covid-19 and Ebola have impacted people's lives significantly. The impact of mobility of people across the countries or states in the spread of epidemics has been significant. The spread of disease due to factors local to the…

Populations and Evolution · Quantitative Biology 2022-05-04 Nirmal Kumar Sivaraman , Manas Gaur , Shivansh Baijal , Sakthi Balan Muthiah , Amit Sheth

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

A better characterization of the early growth dynamics of an epidemic is needed to dissect the important drivers of disease transmission. We introduce a 2-parameter generalized-growth model to characterize the ascending phase of an outbreak…

Quantitative Methods · Quantitative Biology 2016-01-18 Cécile Viboud , Lone Simonsen , Gerardo Chowell

Vector-transmitted diseases such as dengue fever and chikungunya have been spreading rapidly in many parts of the world. The Zika virus has been known since 1947 and invaded South America in 2013. It can be transmitted not only by…

Populations and Evolution · Quantitative Biology 2016-08-23 Fred Brauer , Carlos Castillo-Chavez , Anuj Mubayi , Sherry Towers

Historically, infectious diseases caused considerable damage to human societies, and they continue to do so today. To help reduce their impact, mathematical models of disease transmission have been studied to help understand disease…

We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used. An optimal control…

Optimization and Control · Mathematics 2011-09-19 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Molecular communication is not only able to mimic biological and chemical communication mechanisms, but also provides a theoretical framework for viral infection processes. In this tutorial, aerosol and droplet transmission is modeled as a…

Signal Processing · Electrical Eng. & Systems 2022-01-19 Max Schurwanz , Peter Adam Hoeher , Sunasheer Bhattacharjee , Martin Damrath , Lukas Stratmann , Falko Dressler

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

Social network analysis is now widely used to investigate the dynamics of infectious disease spread from person to person. Vaccination dramatically disrupts the disease transmission process on a contact network, and indeed, sufficiently…

Physics and Society · Physics 2012-11-05 Ellsworth Campbell , Marcel Salathé

This study presents a deterministic model to investigate rabies transmission dynamics, incorporating environmental effects and control strategies using optimal control theory. Qualitative and quantitative analyses reveal that the…

Optimization and Control · Mathematics 2025-09-05 Mfano Charles , Sayoki G. Mfinanga , G. A. Lyakurwa , Delfim F. M. Torres , Verdiana G. Masanja

We present a differential equations model in which contagious disease transmission is affected by contagious fear of the disease and contagious fear of the control, in this case vaccine. The three contagions are coupled. The two fears…

Populations and Evolution · Quantitative Biology 2021-02-23 Joshua M. Epstein , Erez Hatna , Jennifer Crodelle

The humanity has been facing a plethora of challenges associated with infectious diseases, which kill more than 6 million people a year. Although continuous efforts have been applied to relieve the potential damages from such misfortunate…

Artificial Intelligence · Computer Science 2019-05-07 Cheol Young Park , Shou Matsumoto , Jubyung Ha , YoungWon Park

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

Tuberculosis (TB) continues to pose a major public health challenge, particularly in high-burden regions such as Ethiopia, necessitating a more profound understanding of its transmission dynamics. In this study, we developed an SVEITRS…

Populations and Evolution · Quantitative Biology 2025-06-26 Moksina Seyid , Abdu Mohammed Seid , Yassin Tesfaw Abebe

How to prevent the spread of human diseases is a great challenge for the scientific community and so far there are many studies in which immunization strategies have been developed. However, these kind of strategies usually do not consider…

Physics and Society · Physics 2018-08-22 M. A. Di Muro , L. G. Alvarez-Zuzek , S. Havlin , L. A. Braunstein
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