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Biological membranes typically contain a large number of different components dispersed in small concentrations in the main membrane phase, including proteins, sugars, and lipids of varying geometrical properties. Most of these components…

Soft Condensed Matter · Physics 2018-10-17 Tine Curk , Peter Wirnsberger , Jure Dobnikar , Daan Frenkel , Andela Saric

The disk-to-vesicle transition of a fluid membrane with no spontaneous curvature is well described by the competition between edge line and curvature energies. However, the transition of asymmetric membranes with spontaneous curvatures is…

Soft Condensed Matter · Physics 2019-09-24 Hiroshi Noguchi

Morphologies of a vesicle confined in a spherical vesicle were explored experimentally by fast confocal laser microscopy and numerically by a dynamically-triangulated membrane model with area-difference elasticity. The confinement was found…

Soft Condensed Matter · Physics 2014-04-08 Ai Sakashita , Masayuki Imai , Hiroshi Noguchi

The need for organisms to regulate their volume and osmolarity when surrounded by freshwater is a basic physical challenge for many bacteria, protists and algae. Taking inspiration from the contractile vacuole complex found in many…

Biological Physics · Physics 2024-09-24 Sami C. Al-Izzi , Matthew S. Turner , Pierre Sens

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

While the collective motion of active particles has been studied extensively, effective strategies to navigate particle swarms without external guidance remain elusive. We introduce a method to control the trajectories of two-dimensional…

Soft Condensed Matter · Physics 2023-08-28 Sophie Y. Lee , Philipp W. A. Schönhöfer , Sharon C. Glotzer

We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…

Soft Condensed Matter · Physics 2018-05-18 Wen-de Tian , Yong-kun Guo , Kang Chen , Yu-qiang Ma

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

Soft Condensed Matter · Physics 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

An integrated mechanical model for fiber-laden membranes is presented and representative predictions of relevance to cellulose ordering and orientation in the plant cell wall are presented. The model describes nematic liquid crystalline…

Biological Physics · Physics 2009-06-24 Y. K. Murugesan , A. D. Rey

Membrane deformation inside living cells is crucial for the proper shaping of various intracellular organelles and is necessary during the fission/fusion processes that allow membrane recycling and transport (e.g. endocytosis). Proteins…

Biological Physics · Physics 2016-01-20 Urška Jelerčič , Nir S. Gov

Transport of microscopic objects across biological membranes usually involves membrane deformation to enclose the object followed by detachment of the engulfed particle. However, in artificial membranes, this last topological remodelling…

Soft Condensed Matter · Physics 2025-03-25 Florent Fessler , Pierre Muller , Antonio Stocco

In living cells, proteins self-assemble into large functional structures based on specific interactions between molecularly complex patches. Due to this complexity, protein self-assembly results from a competition between a large number of…

Soft Condensed Matter · Physics 2024-12-10 Lara Koehler , Pierre Ronceray , Martin Lenz

Narrow membrane tubes are commonly pulled out from the surface of phospholipid vesicles using forces applied either through laser or magnetic tweezers or through the action of processive motor proteins. Recent examples have emerged where…

Biological Physics · Physics 2019-02-27 Gaurav Kumar , N. Ramakrishnan , Anirban Sain

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

Motivated by recent experiments on biomimetic membranes exposed to several aqueous phases, we theoretically study the morphology of a membrane in contact with a liquid droplet formed via aqueous phase separation. We concentrate on membranes…

Soft Condensed Matter · Physics 2012-02-07 Halim Kusumaatmaja , Reinhard Lipowsky

Understanding the mechanical instabilities of two-dimensional membranes has strong connection to the subjects of structure instabilities, morphology control and materials failures. In this work, we investigate the plastic mechanism…

Soft Condensed Matter · Physics 2024-04-30 Honghui Sun , Zhenwei Yao

Lipid membrane deformations have been predicted to lead to indirect forces between the objects that induce these deformations. Recent experimental measurements have found an attractive interaction between spherical particles that all induce…

Soft Condensed Matter · Physics 2024-11-27 Ali Azadbakht , Daniela J. Kraft

Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends…

Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…

Soft Condensed Matter · Physics 2021-08-17 Chaviva Sirote , Yair Shokef

Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium…

Subcellular Processes · Quantitative Biology 2015-06-26 Tristan Ursell , Kerwyn Huang , Eric Peterson , Rob Phillips