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A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at…

Populations and Evolution · Quantitative Biology 2015-06-16 Alexey Yanchukov , Stephen R. Proulx

The growth of a population divided among spatial sites, with migration between the sites, is sometimes modelled by a product of random matrices, with each diagonal elements representing the growth rate in a given time period, and…

Populations and Evolution · Quantitative Biology 2018-09-12 David Steinsaltz , Shripad Tuljapurkar

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a…

Genomics · Quantitative Biology 2020-09-28 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann

Population genetic studies have found evidence for dramatic population growth in recent human history. It is unclear how this recent population growth, combined with the effects of negative natural selection, has affected patterns of…

Populations and Evolution · Quantitative Biology 2014-02-11 Kirk E. Lohmueller

Evolution occurs in populations of reproducing individuals. The structure of a biological population affects which traits evolve. Understanding evolutionary game dynamics in structured populations is difficult. Precise results have been…

Populations and Evolution · Quantitative Biology 2017-08-16 Benjamin Allen , Gabor Lippner , Yu-Ting Chen , Babak Fotouhi , Naghmeh Momeni , Martin A. Nowak , Shing-Tung Yau

This article is a presentation of specific recent results describing scaling limits of individual-based models. Thanks to them, we wish to relate the time-scales typical of demographic dynamics and natural selection to the parameters of the…

Probability · Mathematics 2023-08-01 Aurélien Velleret

In this work we address the analysis of discrete-time models of structured metapopulations subject to environmental stochasticity. Previous works on these models made use of the fact that migrations between the patches can be considered…

Populations and Evolution · Quantitative Biology 2024-02-07 Luis Sanz , Rafael Bravo de la Parra

We explore a model of metapopulation genetics which is based on a more ecologically motivated approach than is frequently used in population genetics. The size of the population is regulated by competition between individuals, rather than…

Populations and Evolution · Quantitative Biology 2018-05-29 César Parra-Rojas , Alan J. McKane

Environmental changes greatly influence the evolution of populations. Here, we study the dynamics of a population of two strains, one growing slightly faster than the other, competing for resources in a time-varying binary environment…

Populations and Evolution · Quantitative Biology 2020-07-28 Ami Taitelbaum , Robert West , Michael Assaf , Mauro Mobilia

Meta-population networks are effective tools for capturing population movement across distinct regions, but the assumption of well-mixed regions fails to capture the reality of population higher-order interactions. As a multidimensional…

Physics and Society · Physics 2024-06-18 Yanyi Nie , Yanbing Liu , Qixuan Cao , Tao Lin , Wei Wang

Evolution on neutral networks of genotypes has been found in models to concentrate on genotypes with high mutational robustness, to a degree determined by the topology of the network. Here analysis is generalized beyond neutral networks to…

Populations and Evolution · Quantitative Biology 2015-09-01 Lee Altenberg

Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have…

Populations and Evolution · Quantitative Biology 2014-07-30 Wes Maciejewski , Gregory J. Puleo

We study the limit of many small mutations of a model of population dynamics. The population is structured by phonological traits and is spatially inhomogeneous. The various sub-populations compete for the same nutrient which diffuses…

Analysis of PDEs · Mathematics 2016-01-19 Pierre-Emmanuel Jabin , Raymond Strother Schram

We study metanetworks arising in genotype and phenotype spaces, in the context of a model population of Boolean graphs evolved under selection for short dynamical attractors. We define the adjacency matrix of a graph as its genotype, which…

Biological Physics · Physics 2016-09-06 Burçin Danacı , Ayşe Erzan

Human populations have a complex history of introgression and of changing population size. Human genetic variation has been affected by both these processes, so that inference of past population size depends upon the pattern of gene flow…

Populations and Evolution · Quantitative Biology 2017-03-29 John Hawks

The evolution of cooperation often depends upon population structure, yet nearly all models of cooperation implicitly assume that this structure remains static. This is a simplifying assumption, because most organisms possess genetic traits…

Populations and Evolution · Quantitative Biology 2012-08-03 Simon T. Powers , Alexandra S. Penn , Richard A. Watson

Population structure can have a significant effect on evolution. For some systems with sufficient symmetry, analytic results can be derived within the mathematical framework of evolutionary graph theory which relate to the outcome of the…

Populations and Evolution · Quantitative Biology 2019-03-11 Christopher E. Overton , Mark Broom , Christoforos Hadjichrysanthou , Kieran J. Sharkey

Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation. In this paper, we are interested in…

Probability · Mathematics 2016-11-28 Charline Smadi

The distributions of species lifetimes and species in space are related, since species with good local survival chances have more time to colonize new habitats and species inhabiting large areas have higher chances to survive local…

Populations and Evolution · Quantitative Biology 2019-02-18 Tobias Rogge , David Jones , Barbara Drossel , Korinna T. Allhoff

Over the last fifty years, geneticists have made great strides in understanding how our species' evolutionary history gave rise to current patterns of human genetic diversity classically summarized by Lewontin in his 1972 paper, 'The…

Populations and Evolution · Quantitative Biology 2022-02-14 Shyamalika Gopalan , Samuel Patillo Smith , Katharine Korunes , Iman Hamid , Sohini Ramachandran , Amy Goldberg