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We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their…

Biological Physics · Physics 2018-03-28 David J. Jörg , Luis G. Morelli , Frank Jülicher

Linearized catalytic reaction equations modeling e.g. the dynamics of genetic regulatory networks under the constraint that expression levels, i.e. molecular concentrations of nucleic material are positive, exhibit nontrivial dynamical…

Disordered Systems and Neural Networks · Physics 2015-05-18 Rudolf Hanel , Manfred Pöchacker , Stefan Thurner

Statistical models provide a powerful and useful class of approximations for calculating reaction rates by bypassing the need for detailed, and often difficult, dynamical considerations. Such approaches invariably invoke specific…

Chemical Physics · Physics 2020-04-01 Sourav Karmakar , Pankaj Kumar Yadav , Srihari Keshavamurthy

How can we efficiently propagate uncertainty in a latent state representation with recurrent neural networks? This paper introduces stochastic recurrent neural networks which glue a deterministic recurrent neural network and a state space…

Machine Learning · Statistics 2016-11-15 Marco Fraccaro , Søren Kaae Sønderby , Ulrich Paquet , Ole Winther

We study the emergence and coherence of stochastic oscillations in star networks of excitable elements in which peripheral nodes receive independent random inputs. A biophysical model of a distal branch of sensory neuron in which peripheral…

Biological Physics · Physics 2016-04-21 Justus A. Kromer , Lutz Schimansky-Geier , Alexander B. Neiman

We consider a general class of stochastic networks and ask which network nodes need to be controlled, and how, to stabilize and switch between desired metastable (target) states in terms of the first and second statistical moments of the…

Adaptation and Self-Organizing Systems · Physics 2016-07-20 Dmytro Bielievtsov , Josef Ladenbauer , Klaus Obermayer

We quantify the effect of Gaussian white noise on fast--slow dynamical systems with one fast and two slow variables, which display mixed-mode oscillations owing to the presence of a folded-node singularity. The stochastic system can be…

Dynamical Systems · Mathematics 2015-03-06 Nils Berglund , Barbara Gentz , Christian Kuehn

Reaction networks are systems in which the populations of a finite number of species evolve through predefined interactions. Such networks are found as modeling tools in many biological disciplines such as biochemistry, ecology,…

Molecular Networks · Quantitative Biology 2015-06-15 Ankit Gupta , Corentin Briat , Mustafa Khammash

Genes are connected in complex networks of interactions where often the product of one gene is a transcription factor that alters the expression of another. Many of these networks are based on a few fundamental motifs leading to switches…

Molecular Networks · Quantitative Biology 2026-03-05 Zitao Yang , Rebecca J. Rousseau , Sara D. Mahdavi , Hernan G. Garcia , Rob Phillips

Oscillatory activity is ubiquitous in natural and engineered network systems. The interaction scheme underlying interdependent oscillatory components governs the emergence of network-wide patterns of synchrony that regulate and enable…

Adaptation and Self-Organizing Systems · Physics 2022-08-12 Tommaso Menara , Giacomo Baggio , Danielle S. Bassett , Fabio Pasqualetti

Numerous social, medical, engineering and biological challenges can be framed as graph-based learning tasks. Here, we propose a new feature based approach to network classification. We show how dynamics on a network can be useful to reveal…

Machine Learning · Statistics 2017-06-01 Leonardo Gutierrez Gomez , Benjamin Chiem , Jean-Charles Delvenne

Many natural and man-made network systems need to maintain certain patterns, such as working at equilibria or limit cycles, to function properly. Thus, the ability to stabilize such patterns is crucial. Most of the existing studies on…

Optimization and Control · Mathematics 2025-09-30 Alberto Maria Nobili , Yuzhen Qin , Carlo Alberto Avizzano , Danielle S. Bassett , Fabio Pasqualetti

We consider a model of large regulatory gene expression networks where the thresholds activating the sigmoidal interactions between genes and the signs of these interactions are shuffled randomly. Such an approach allows for a qualitative…

Molecular Networks · Quantitative Biology 2007-05-23 D. Volchenkov , R. Lima

We present a method to infer network connectivity from collective dynamics in networks of synchronizing phase oscillators. We study the long-term stationary response to temporally constant driving. For a given driving condition, measuring…

Disordered Systems and Neural Networks · Physics 2009-11-11 Marc Timme

There is enormous interest -- both mathematically and in diverse applications -- in understanding the dynamics of coupled oscillator networks. The real-world motivation of such networks arises from studies of the brain, the heart, ecology,…

Dynamical Systems · Mathematics 2023-08-22 Stephen Coombes , Mustafa Sayli , Rüdiger Thul , Rachel Nicks , Mason A Porter , Yi Ming Lai

We study the mobility of an overdamped particle in a periodic potential tilted by a constant force. The mobility exhibits a stochastic resonance in inhomogeneous systems with space dependent friction coefficient. The result indicates that…

Statistical Mechanics · Physics 2009-10-31 Debasis Dan , Mangal. C. Mahato , A. M. Jayannavar

To probe the connection between the dynamic phase transition and stochastic resonance, we study the mean-field kinetic Ising model and the two-dimensional Josephson-junction array in the presence of appropriate oscillating magnetic fields.…

Statistical Mechanics · Physics 2007-05-23 Beom Jun Kim , Petter Minnhagen , Hyun Jin Kim , M. Y. Choi , Gun Sang Jeon

Ultrafast disordering observed after photo-excitation challenges the conventional picture of photo-induced transitions where symmetry-breaking takes place along a single collective coordinate. We propose that key spectroscopic signatures of…

Strongly Correlated Electrons · Physics 2025-07-31 Francesco Valiera , Antonio Picano , Martin Eckstein

The archetypal system demonstrating stochastic resonance is nothing more than a threshold triggered device. It consists of a periodic modulated input and noise. Every time an output crosses the threshold the signal is recorded. Such a…

Statistical Mechanics · Physics 2014-01-10 Krzysztof Szczepaniec , Bartlomiej Dybiec

Dynamic networks models describe a growing number of important scientific processes, from cell biology and epidemiology to sociology and finance. There are many aspects of dynamical networks that require statistical considerations. In this…

Methodology · Statistics 2012-05-15 E. C. Wit , A. Abbruzzo