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Steady state is an essential concept in reaction networks. Its stability reflects fundamental characteristics of several biological phenomena such as cellular signal transduction and gene expression. Because biochemical reactions occur at…

Molecular Networks · Quantitative Biology 2019-04-19 Tan Van Vu , Yoshihiko Hasegawa

Adaptive networks model social, physical, technical, or biological systems as attributed graphs evolving at the level of both their topology and data. They are naturally described by graph transformation, but the majority of authors take an…

Discrete Mathematics · Computer Science 2021-12-22 Nicolas Behr , Bello Shehu Bello , Sebastian Ehmes , Reiko Heckel

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

Methodology · Statistics 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

For dynamical systems that can be modelled as asymptotically stable linear systems forced by Gaussian noise, this paper develops methods to infer or estimate their modes from observations in real time. The modes can be real or complex. For…

Machine Learning · Statistics 2019-10-30 Robert S. MacKay

Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states…

Molecular Networks · Quantitative Biology 2018-06-27 M. Ali Al-Radhawi , Domitilla Del Vecchio , Eduardo D. Sontag

A central question of network science is how functional properties of systems arise from their structure. For networked dynamical systems, structure is typically quantified with network measures. A functional property that is of theoretical…

Adaptation and Self-Organizing Systems · Physics 2024-02-28 Christian Nauck , Michael Lindner , Nora Molkenthin , Jürgen Kurths , Eckehard Schöll , Jörg Raisch , Frank Hellmann

Stochastic reaction network models are widely utilized in biology and chemistry to describe the probabilistic dynamics of biochemical systems in general, and gene interaction networks in particular. Most often, statistical analysis and…

Quantitative Methods · Quantitative Biology 2017-10-18 Eugenio Cinquemani

We propose a stochastic dynamical model of noisy neural networks with complex architectures and discuss activation of neural networks by a stimulus, pacemakers and spontaneous activity. This model has a complex phase diagram with…

Disordered Systems and Neural Networks · Physics 2015-05-13 A. V. Goltsev , F. V. de Abreu , S. N. Dorogovtsev , J. F. F. Mendes

Regulatory networks describe the interactions between molecular or cellular regulators, like transcription factors and genes in gene regulatory networks, kinases and their receptors in signalling networks, or neurons in neural networks. A…

Molecular Networks · Quantitative Biology 2022-12-29 Niklas Bonacker , Johannes Berg

Robust oscillations play crucial roles in a wide variety of biological processes and are often generated by deterministic mechanisms. However, stochastic fluctuations often generate complex perturbations of these deterministic oscillations,…

Dynamical Systems · Mathematics 2026-03-27 Xuesong Bai , Jonathan Touboul , Thomas G. Fai

We analyze transport on a graph with multiple constraints and where the weight of the edges connecting the nodes is a dynamical variable. The network dynamics results from the interplay between a nonlinear function of the flow, dissipation,…

Statistical Mechanics · Physics 2023-11-28 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

It is by now established that, remarkably, the addition of noise to a nonlinear system may sometimes facilitate, rather than hamper the detection of weak signals. This phenomenon, usually referred to as stochastic resonance, was originally…

Condensed Matter · Physics 2009-10-31 Redouane Fakir

A nonlinear oscillator with an abruptly inhomogeneous restoring force driven by an uniform oscillating force exhibits stochastic properties under specific resonance conditions. This behaviour elucidates the elementary mechanism of the…

Plasma Physics · Physics 2015-05-19 S. V. Bulanov , A. Yogo , T. Zh. Esirkepov , J. K. Koga , S. S. Bulanov , K. Kondo , M. Kando

Although stochastic resonance phenomena are ubiquitous across various complex systems, the influence mechanisms of higher-order interactions remain elusive. Here, we address this gap by investigating stochastic resonance in coupled phase…

Adaptation and Self-Organizing Systems · Physics 2026-03-16 Zheng Wang , Jinjie Zhu , Xianbin Liu

The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. It is found that there are…

Molecular Networks · Quantitative Biology 2009-11-11 Ovidiu Lipan , Wing H. Wong

Graphs have become pervasive tools to represent information and datasets with irregular support. However, in many cases, the underlying graph is either unavailable or naively obtained, calling for more advanced methods to its estimation.…

Signal Processing · Electrical Eng. & Systems 2023-03-14 Andrei Buciulea , Antonio G. Marques

We analyze the phenomenon of stochastic resonance in an Ising-like system on a small-world network. The system, which is subject to the combined action of noise and an external modulation, can be interpreted as a stylized model of opinion…

Disordered Systems and Neural Networks · Physics 2009-11-07 Marcelo Kuperman , Damian Zanette

Can one hear the shape of a graph? This is a modification of the famous question of Mark Kac "Can one hear the shape of a drum?" which can be asked in the case of scattering systems such as quantum graphs and microwave networks. It…

Optics · Physics 2014-05-07 Michal Lawniczak , Adam Sawicki , Szymon Bauch , Marek Kus , Leszek Sirko

Ring topologies of repressing genes have qualitatively different long-term dynamics if the number of genes is odd (they oscillate) or even (they exhibit bistability). However, these attractors may not fully explain the observed behavior in…

Molecular Networks · Quantitative Biology 2010-01-22 Natalja Strelkowa , Mauricio Barahona

Networks serve as a tool used to examine the large-scale connectivity patterns in complex systems. Modelling their generative mechanism nonparametrically is often based on step-functions, such as the stochastic block models. These models…

Methodology · Statistics 2024-01-11 Arthur Verdeyme , Sofia C. Olhede