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From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

The structural network of the brain, or structural connectome, can be represented by fiber bundles generated by a variety of tractography methods. While such methods give qualitative insights into brain structure, there is controversy over…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Kristen M. Campbell , Haocheng Dai , Zhe Su , Martin Bauer , P. Thomas Fletcher , Sarang C. Joshi

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

Applications · Statistics 2026-05-25 J. M. Gorriz , F. Segovia , C. Jimenez , J. E. Arco , F. J. Martinez , J Ramirez , S. Abulikemu , J. Suckling

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Deep learning has a great potential for estimating biomarkers in diffusion weighted magnetic resonance imaging (dMRI). Atlases, on the other hand, are a unique tool for modeling the spatio-temporal variability of biomarkers. In this paper,…

Medical Physics · Physics 2022-05-09 Davood Karimi , Ali Gholipour

We propose a deep neural network for supervised learning on neuroanatomical shapes. The network directly operates on raw point clouds without the need for mesh processing or the identification of point correspondences, as spatial…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Benjamin Gutierrez-Becker , Christian Wachinger

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

Machine Learning · Statistics 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

In recent years, several studies have provided insight on the functioning of the brain which consists of neurons and form networks via interconnection among them by synapses. Neural networks are formed by interconnected systems of neurons,…

Neurons and Cognition · Quantitative Biology 2021-01-22 Martin C. Nwadiugwu

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

Current atlas-based approaches to brain network analysis rely heavily on standardized anatomical or connectivity-driven brain atlases. However, these fixed atlases often introduce significant limitations, such as spatial misalignment across…

Neurons and Cognition · Quantitative Biology 2026-02-27 Shuai Huang , Xuan Kan , James J. Lah , Deqiang Qiu

Artificial neural networks (ANNs), originally inspired by biological neural networks (BNNs), have achieved remarkable successes in many tasks such as visual representation learning. However, whether there exists semantic…

Computer Vision and Pattern Recognition · Computer Science 2022-06-23 Lin Zhao , Haixing Dai , Zihao Wu , Zhenxiang Xiao , Lu Zhang , David Weizhong Liu , Xintao Hu , Xi Jiang , Sheng Li , Dajiang Zhu , Tianming Liu

Three-dimensional (3D) reconstruction of head Computed Tomography (CT) images elucidates the intricate spatial relationships of tissue structures, thereby assisting in accurate diagnosis. Nonetheless, securing an optimal head CT scan…

Computer Vision and Pattern Recognition · Computer Science 2023-09-18 Bowen Zheng , Chenxi Huang , Yuemei Luo

Brain extraction (skull stripping) is a challenging problem in neuroimaging. It is due to the variability in conditions from data acquisition or abnormalities in images, making brain morphology and intensity characteristics changeable and…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Duy H. M. Nguyen , Duy M. Nguyen , Mai T. N. Truong , Thu Nguyen , Khanh T. Tran , Nguyen A. Triet , Pham T. Bao , Binh T. Nguyen

Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

Machine Learning · Computer Science 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

Multi-atlas segmentation is a widely used tool in medical image analysis, providing robust and accurate results by learning from annotated atlas datasets. However, the availability of fully annotated atlas images for training is limited due…

Computer Vision and Pattern Recognition · Computer Science 2016-05-03 Lisa M. Koch , Martin Rajchl , Wenjia Bai , Christian F. Baumgartner , Tong Tong , Jonathan Passerat-Palmbach , Paul Aljabar , Daniel Rueckert

In the medical field, landmark detection in MRI plays an important role in reducing medical technician efforts in tasks like scan planning, image registration, etc. First, 88 landmarks spread across the brain anatomy in the three respective…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Muhammad Ilyas Patel , Shrey Singla , Razeem Ahmad Ali Mattathodi , Sumit Sharma , Deepam Gautam , Srinivasa Rao Kundeti

Foundation models are emerging as a powerful paradigm for fMRI analysis, but current approaches face a dual bottleneck of data- and training-efficiency. Atlas-based methods aggregate voxel signals into fixed regions of interest, reducing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Mo Wang , Junfeng Xia , Wenhao Ye , Enyu Liu , Kaining Peng , Jianfeng Feng , Quanying Liu , Hongkai Wen
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