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This paper presents a variational framework for dense diffeomorphic atlas-mapping onto high-throughput histology stacks at the 20 um meso-scale. The observed sections are modelled as Gaussian random fields conditioned on a sequence of…

Image and Video Processing · Electrical Eng. & Systems 2019-03-06 Brian C. Lee , Daniel J. Tward , Partha P. Mitra , Michael I. Miller

Active learning is a unique abstraction of machine learning techniques where the model/algorithm could guide users for annotation of a set of data points that would be beneficial to the model, unlike passive machine learning. The primary…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Vishwesh Nath , Dong Yang , Bennett A. Landman , Daguang Xu , Holger R. Roth

Alzheimer's disease (AD) is associated with local (e.g. brain tissue atrophy) and global brain changes (loss of cerebral connectivity), which can be detected by high-resolution structural magnetic resonance imaging. Conventionally, these…

Machine Learning · Computer Science 2021-05-11 Sarah C. Brüningk , Felix Hensel , Catherine R. Jutzeler , Bastian Rieck

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Precise identification of mouse brain microscopy images is a crucial first step when anatomical structures in the mouse brain are to be registered to a reference atlas. Practitioners usually rely on manual comparison of images or tools that…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Justinas Antanavicius , Roberto Leiras , Raghavendra Selvan

Motor brain-computer interfaces (BCIs) enable the control of external devices by decoding neural signals. However, most existing systems rely on a direct "brain-machine" mapping, overlooking the hierarchical physiological pathway of natural…

Human-Computer Interaction · Computer Science 2025-12-18 Ye Sun , Bowei Zhao , Dezhong Yao , Rui Zhang , Bohan Zhang , Xiaoyuan Li , Jing Wang , Mingxuan Qu , Gang Liu

Image registration between histology and magnetic resonance imaging (MRI) is a challenging task due to differences in structural content and contrast. Too thick and wide specimens cannot be processed all at once and must be cut into smaller…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Jonas Pichat , Juan Eugenio Iglesias , Sotiris Nousias , Tarek Yousry , Sebastien Ourselin , Marc Modat

Automatic brain tissue segmentation from Magnetic Resonance Imaging (MRI) images is vital for accurate diagnosis and further analysis in medical imaging. Despite advancements in segmentation techniques, a comprehensive comparison between…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Mohammad Imran Hossain , Muhammad Zain Amin , Daniel Tweneboah Anyimadu , Taofik Ahmed Suleiman

This paper introduces a novel approach that combines unsupervised active contour models with deep learning for robust and adaptive image segmentation. Indeed, traditional active contours, provide a flexible framework for contour evolution…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Antoine Habis , Vannary Meas-Yedid , Elsa Angelini , Jean-Christophe Olivo-Marin

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

The automatic segmentation of perinatal brain structures in magnetic resonance imaging (MRI) is of utmost importance for the study of brain growth and related complications. While different methods exist for adult and pediatric MRI data,…

Brain atlases are a ubiquitous tool used for analyzing and interpreting brain imaging datasets. Traditionally, brain atlases divided the brain into regions separated by anatomical landmarks. In the last decade, several attempts have been…

Quantitative Methods · Quantitative Biology 2018-02-08 Pantea Moghimi , Kelvin O. Lim , Theoden I. Netoff

Purpose: To develop the first 3D optic nerve head (ONH) atlas using AI-based registration and evaluate its use in: (1) atlas-adjusted retinal nerve fiber layer (RNFL) analysis for glaucoma diagnosis, and (2) strain-based assessment of…

This paper investigates the multi-agent cooperative exploration problem, which requires multiple agents to explore an unseen environment via sensory signals in a limited time. A popular approach to exploration tasks is to combine active…

Robotics · Computer Science 2023-11-02 Xinyi Yang , Yuxiang Yang , Chao Yu , Jiayu Chen , Jingchen Yu , Haibing Ren , Huazhong Yang , Yu Wang

Brain network discovery aims to find nodes and edges from the spatio-temporal signals obtained by neuroimaging data, such as fMRI scans of human brains. Existing methods tend to derive representative or average brain networks, assuming…

Machine Learning · Computer Science 2023-11-07 Hang Yin , Yao Su , Xinyue Liu , Thomas Hartvigsen , Yanhua Li , Xiangnan Kong

Precise segmentation of brain structures in magnetic resonance imaging (MRI) is essential for reliable neuroimaging analysis, yet voxel-wise deep models often yield anatomically inconsistent results that diverge from expert-defined…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Ahmed Rekik , R. Jarrett Rushmore , Sylvain Bouix , Linda Marrakchi-Kacem

Explicit neural surface representations allow for exact and efficient extraction of the encoded surface at arbitrary precision, as well as analytic derivation of differential geometric properties such as surface normal and curvature. Such…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Weng Fei Low , Gim Hee Lee

Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy. Historically, multi-atlas segmentation (MAS) has been regarded as the de facto standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Yuankai Huo , Zhoubing Xu , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman