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Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion. Active and advective transport…

Biological Physics · Physics 2012-07-24 P. Khuc Trong , J. Guck , R. E. Goldstein

Experiments have found that diffusion in metabolically active cells is much faster than in dormant cells, especially for large particles. However, the mechanism of this size-dependent diffusion enhancement in living cells is still unclear.…

Biological Physics · Physics 2023-04-04 Lingyu Meng , Yiteng Jin , Yichao Guan , Jiayi Xu , Jie Lin

It is now well established that the cell is a highly crowded environment. Yet, the effects of crowding on the dynamics of signaling pathways, gene regulation networks and metabolic networks are still largely unknown. Crowding can alter both…

Molecular Networks · Quantitative Biology 2013-11-19 Pieter Rein ten Wolde , Andrew Mugler

We perform numerical simulations of isolated, partially active polymers, driven out-of-equilibrium by a fraction of their monomers. We show that, if the active beads are all gathered in a contiguous block, the position of the section along…

Soft Condensed Matter · Physics 2023-09-04 Marin Vatin , Sumanta Kundu , Emanuele Locatelli

Using molecular dynamics simulations, we report phase separation in a 50:50 mixture of hot(active) and cold(passive) dumbbells which interact by Lennard-Jones potential. The ratio of the temperature difference between hot and cold dumbbells…

Soft Condensed Matter · Physics 2021-09-02 Nayana V , Shiang-Tai Lin , Prabal K Maiti

We theoretically study the transport properties of self-propelled particles on complex structures, such as motor proteins on filament networks. A general master equation formalism is developed to investigate the persistent motion of…

Soft Condensed Matter · Physics 2014-09-19 M. Reza Shaebani , Zeinab Sadjadi , Igor M. Sokolov , Heiko Rieger , Ludger Santen

In intracellular transports, motor proteins transport macromolecules as cargos to desired locations by moving on biopolymers such as microtubules. Recent experiments suggest that cargos that can associate motor proteins during their…

Biological Physics · Physics 2023-07-04 Sutapa Mukherji , Dhruvi K. Patel

Catalytically active macromolecules are envisioned as key building blocks in development of artificial nanomotors. However, theory and experiments report conflicting findings regarding their dynamics. The lack of consensus is mostly caused…

Statistical Mechanics · Physics 2022-09-15 Artem Ryabov , Mykola Tasinkevych

Biological systems commonly combine intrinsically out-of-equilibrium active components with passive polymeric inclusions to produce unique material properties. To explore these composite systems, idealized models - such as polymers in…

Soft Condensed Matter · Physics 2025-03-27 Zahra K. Valei , Tyler N. Shendruk

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

In this work we study analytically and numerically the transport properties of non-interacting active particles moving on a $d$-dimensional disordered media. The disorder in the space is modeled by means of a set of non-overlapping…

Statistical Mechanics · Physics 2022-07-20 R. Salgado-García

Active particle systems of interacting self-propelled particles offer a versatile framework for modeling complex systems. When employed to describe aspects of animal behavior, the complexity of animal movement and decision-making often…

Biological Physics · Physics 2025-01-09 Amir Haluts , Dan Gorbonos , Nir S. Gov

Active turbulence in dense active systems is characterized by high vorticity on a length scale that is large compared to that of individual entities. We describe the properties of active turbulence as momentum propagation is screened by…

Soft Condensed Matter · Physics 2014-12-24 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

Diffusion of a two component fluid is studied in the framework of differential equations, but where these equations are systematically derived from a well-defined microscopic model. The model has a finite carrying capacity imposed upon it…

Statistical Mechanics · Physics 2015-06-04 D. Fanelli , A. J. McKane , G. Pompili , B. Tiribilli , M. Vassalli , T. Biancalani

We expand on a recent study of a lattice model of interacting particles [Phys. Rev. Lett. 111, 110601 (2013)]. The adsorption isotherm and equilibrium fluctuations in particle number are discussed as a function of the interaction. Their…

Statistical Mechanics · Physics 2014-11-20 T. Becker , K. Nelissen , B. Cleuren , B. Partoens , C. Van den Broeck

Active particles contain internal degrees of freedom with the ability to take in and dissipate energy and, in the process, execute systematic movement. Examples include all living organisms and their motile constituents such as molecular…

Soft Condensed Matter · Physics 2015-05-18 Sriram Ramaswamy

Systems switching between different dynamical phases is an ubiquitous phenomenon. The general understanding of such a process is limited. To this end, we present a general expression that captures fluctuations of a system exhibiting a…

Statistical Mechanics · Physics 2024-12-05 Ion Santra , Kristian Stølevik Olsen , Deepak Gupta

Active matter exhibits striking behaviour reminiscent of living matter and molecular fluids, and has promising applications in drug delivery or mixing at the micron scale. Active colloidal systems provide important models with simple and…

Soft Condensed Matter · Physics 2020-10-09 Nariaki Sakaï , C. Patrick Royall

We investigate the effect of cooperative interactions in an ensemble of microorganisms, modelled as self-propelled disk-like and rod-like particles, in a three-dimensional turbulent flow to show flocking as an emergent phenomenon. Building…

Soft Condensed Matter · Physics 2020-05-20 Anupam Gupta , Amal Roy , Arnab Saha , Samriddhi Sankar Ray

Using scaling arguments and extensive numerical simulations, we study dynamics of a tracer particle in a corrugated channel represented by a periodic sequence of broad chambers and narrow funnel-like bottlenecks enclosed by a hard-wall…

Statistical Mechanics · Physics 2023-07-19 A. Valov , V. Avetisov , S. Nechaev , G. Oshanin
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