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Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Joël Mathys , Andreas Plesner , Jorel Elmiger , Roger Wattenhofer

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

Neurons and Cognition · Quantitative Biology 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

Manufacturing-viable neuromorphic chips require novel computer architectures to achieve the massively parallel and efficient information processing the brain supports so effortlessly. Emerging event-based architectures are making this dream…

Hardware Architecture · Computer Science 2023-01-25 Lennart Bamberg , Arash Pourtaherian , Luc Waeijen , Anupam Chahar , Orlando Moreira

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

Neurons and Cognition · Quantitative Biology 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

Machine Learning · Computer Science 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

In this paper, we present MicroNet, which is an efficient convolutional neural network using extremely low computational cost (e.g. 6 MFLOPs on ImageNet classification). Such a low cost network is highly desired on edge devices, yet usually…

Computer Vision and Pattern Recognition · Computer Science 2020-11-25 Yunsheng Li , Yinpeng Chen , Xiyang Dai , Dongdong Chen , Mengchen Liu , Lu Yuan , Zicheng Liu , Lei Zhang , Nuno Vasconcelos

The current neuron reconstruction pipeline for electron microscopy (EM) data usually includes automatic image segmentation followed by extensive human expert proofreading. In this work, we aim to reduce human workload by predicting…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Qihua Chen , Xuejin Chen , Chenxuan Wang , Yixiong Liu , Zhiwei Xiong , Feng Wu

Efforts to automate the reconstruction of neural circuits from 3D electron microscopic (EM) brain images are critical for the field of connectomics. An important computation for reconstruction is the detection of neuronal boundaries. Images…

Computer Vision and Pattern Recognition · Computer Science 2015-08-21 Kisuk Lee , Aleksandar Zlateski , Ashwin Vishwanathan , H. Sebastian Seung

We present compositional nearest neighbors (CompNN), a simple approach to visually interpreting distributed representations learned by a convolutional neural network (CNN) for pixel-level tasks (e.g., image synthesis and segmentation). It…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Victor Fragoso , Chunhui Liu , Aayush Bansal , Deva Ramanan

A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2,…

Neurons and Cognition · Quantitative Biology 2017-06-13 Pawe Dotko , Kathryn Hess , Ran Levi , Max Nolte , Michael Reimann , Martina Scolamiero , Katharine Turner , Eilif Muller , Henry Markram

Producing connectomes from electron microscopy (EM) images has historically required a great deal of human proofreading effort. This manual annotation cost is the current bottleneck in scaling EM connectomics, for example, in making larger…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Gary B Huang , William M Katz , Stuart Berg , Louis Scheffer

Semantic segmentation requires methods capable of learning high-level features while dealing with large volume of data. Towards such goal, Convolutional Networks can learn specific and adaptable features based on the data. However, these…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Keiller Nogueira , Mauro Dalla Mura , Jocelyn Chanussot , William R. Schwartz , Jefersson A. dos Santos

Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal…

Neurons and Cognition · Quantitative Biology 2015-07-28 Yury V. Zaytsev , Abigail Morrison , Moritz Deger

We introduce an approach to integrate segmentation information within a convolutional neural network (CNN). This counter-acts the tendency of CNNs to smooth information across regions and increases their spatial precision. To obtain…

Computer Vision and Pattern Recognition · Computer Science 2017-08-16 Adam W. Harley , Konstantinos G. Derpanis , Iasonas Kokkinos

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

Spontaneous neural activity, crucial in memory, learning, and spatial navigation, often manifests itself as repetitive spatiotemporal patterns. Despite their importance, analyzing these patterns in large neural recordings remains…

Signal Processing · Electrical Eng. & Systems 2024-05-15 Roman Koshkin , Tomoki Fukai

During the past two decades, epileptic seizure detection and prediction algorithms have evolved rapidly. However, despite significant performance improvements, their hardware implementation using conventional technologies, such as…

Emerging Technologies · Computer Science 2025-01-30 Chenqi Li , Corey Lammie , Xuening Dong , Amirali Amirsoleimani , Mostafa Rahimi Azghadi , Roman Genov
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