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Nowadays, there is a growing interest in the field of magnetic particle spectroscopy (MPS)-based bioassays. MPS monitors the dynamic magnetic response of surface-functionalized magnetic nanoparticles (MNPs) upon excitation by an alternating…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vinit Kumar Chugh , Arturo di Girolamo , Venkatramana D. Krishna , Kai Wu , Maxim C-J Cheeran , Jian-Ping Wang

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

We propose Microscopic Propagator Imaging (MPI) as a novel method to retrieve the indices of the microscopic propagator which is the probability density function of water displacements due to diffusion within the nervous tissue…

Neurons and Cognition · Quantitative Biology 2025-03-03 Tommaso Zajac , Gloria Menegaz , Marco Pizzolato

Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality that derives much of its contrast from microscale magnetic field gradients in biological tissues. However, the connection between these sub-voxel field patterns…

In all of medical profession a broad field of research is dedicated to seek less invasive and low-risk forms of therapy with the ultimate goal of non-invasive therapy, particularly in neoplasmic diseases. Theranostic platforms, combining…

Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that images the spatial distribution of superparamagnetic iron oxide (SPIO) nanoparticles using their nonlinear response to applied magnetic fields. In standard x-space…

Medical Physics · Physics 2019-12-11 Semih Kurt , Yavuz Muslu , Emine Ulku Saritas

Significance: Voltage imaging microscopy has emerged as a powerful tool to investigate neural activity both in vivo and in vitro. Various imaging approaches have been developed, including point-scanning, line-scanning and wide-field…

Optics · Physics 2026-01-29 Jakub Czuchnowski , Jerome Mertz

Magnetic Resonance Imaging (MRI) can be considered one of the most effective techniques in both clinical diagnostic medical field and biomedicine, as it allows to obtain images anatomy of the body and its various parts and information…

Fluid Dynamics · Physics 2011-02-02 Stefania Nicolosi

Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…

Medical Physics · Physics 2022-07-13 Klaas-Julian Janssen , Meinhard Schilling , Frank Ludwig , Jing Zhong

Magnetic particle imaging (MPI) is a tracer-based medical imaging modality that enables quantification and spatial mapping of magnetic nanoparticle (MNP) distribution. The magnetization response of MNPs depends on experimental conditions…

Signal Processing · Electrical Eng. & Systems 2025-09-03 Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

Magnetic resonance imaging (MRI) is the cornerstone technique for diagnostic medicine, biology, and neuroscience. This imaging method is highly innovative, noninvasive and its impact continues to grow. It can be used for measuring changes…

This work demonstrates nanoscale magnetic imaging using bright circularly polarized high-harmonic radiation. We utilize the magneto-optical contrast of worm-like magnetic domains in a Co/Pd multilayer structure, obtaining quantitative…

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

Scanning electron microscopy with polarization analysis is a powerful lab-based magnetic imaging technique offering parallel imaging of multiple magnetization components and a very high spatial resolution. However, one drawback of the…

Instrumentation and Detectors · Physics 2018-08-22 Daniel Schönke , Andreas Oelsner , Pascal Krautscheid , Robert M. Reeve , Mathias Kläui

The aim of this paper is to provide a solid mathematical discussion of the inverse problem in Magnetorelaxometry Imaging (MRXI), a currently developed technique for quantitative biomedical imaging using magnetic nanoparticles. We provide a…

Numerical Analysis · Mathematics 2021-09-24 Lea Föcke , Daniel Baumgarten , Martin Burger

We report on our progress in the development of an atomic magnetometer (AM) based low-frequency magnetic particle imaging (MPI) scanner, expected to be free from Specific Absorption Rate (SAR) and Peripheral Nerve Stimulation (PNS)…

Instrumentation and Detectors · Physics 2017-01-16 Simone Colombo , Victor Lebedev , Alexey Tonyushkin , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool that provides excellent soft-tissue contrast without the use of ionizing radiation. Compared to other clinical imaging modalities (e.g., CT or ultrasound), however, the data…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Rizwan Ahmad , Charles A. Bouman , Gregery T. Buzzard , Stanley Chan , Sizhou Liu , Edward T. Reehorst , Philip Schniter

MALDI mass spectrometry imaging (MALDI MSI) is a spatially resolved analytical tool for biological tissue analysis by measuring mass-to-charge ratios of ionized molecules. With increasing spatial and mass resolution of MALDI MSI data,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-04 Florian Lieb , Tobias Boskamp , Hans-Georg Stark