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Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.…

Cell Behavior · Quantitative Biology 2015-06-24 Javad Noorbakhsh , David Schwab , Allyson Sgro , Thomas Gregor , Pankaj Mehta

We develop theoretical equivalences between stochastic and deterministic models for populations of individual cells stratified by age. Specifically, we develop a hierarchical system of equations describing the full dynamics of an…

Populations and Evolution · Quantitative Biology 2022-06-29 Joshua C. Kynaston , Chris Guiver , Christian A. Yates

We investigate a 2D dynamical absorbing state model of monodisperse disks, in which rich phase behavior arises from interactions consisting solely of repulsive displacements between overlapping particles. The phase diagram reveals several…

Soft Condensed Matter · Physics 2025-12-23 Ashley Z. Guo , Sam Wilken , Dov Levine , Paul M. Chaikin

Swimming microbes, such as bacteria and algae, live in diverse habitats including soil, ocean and human body which are characterized by structural boundaries and heterogeneous fluid flows. Although much progress has been made in…

Biological Physics · Physics 2022-02-16 Kejie Chen , Kairong Qin

We present a joint experimental and computational study of the effect of bacterial motion on micron-scale colloids contained in a two-dimensional suspension of Bacillus subtilis. With respect to previous work using E. coli, here we…

Soft Condensed Matter · Physics 2011-09-20 Chantal Valeriani , Martin Li , John Novosel , Jochen Arlt , Davide Marenduzzo

This study explores the application of elongated particle interaction models, traditionally used in liquid crystal phase research, in the context of early bacterial biofilm development. Through computer simulations using an agent-based…

Soft Condensed Matter · Physics 2025-11-05 Gabriel Santos-Díaz , Álvaro Rodríguez-Rivas , Alejandro Cuetos

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

Electrical waves in the heart form rotating spiral or scroll waves during life-threatening arrhythmias such as atrial or ventricular fibrillation. The wave dynamics are typically modeled using coupled partial differential equations, which…

Medical Physics · Physics 2024-10-07 Tanish Baranwal , Jan Lebert , Jan Christoph

We investigate a recently proposed cross-diffusion system modelling the growth of gliobastoma taking into account size exclusion both in the migration and proliferation process. In addition to degenerate nonlinear cross-diffusion the model…

Analysis of PDEs · Mathematics 2017-10-12 Martin Burger , Patricia Friele , Jan-Frederik Pietschmann

It has been argued that there is biological and modeling evidence that a non-linear diffusion coefficient of the type D(b) = D_0 b^{k} underlies the formation of a number of growth patterns of bacterial colonies. We study a…

Statistical Mechanics · Physics 2016-08-31 J. Mueller , W. van Saarloos

Bioconvection, a phenomenon arising from the collective motion of motile microorganisms, plays a crucial role in shaping microbial distributions, fluid dynamics, and bloom formation in aquatic environments. While extensive research has…

Biological Physics · Physics 2025-04-15 Samarendu Biswas , Sachidananda Mahato , Jayabrata Dhar

Among the main actors of organism development there are morphogens, which are signaling molecules diffusing in the developing organism and acting on cells to produce local responses. Growth is thus determined by the distribution of such…

Optimization and Control · Mathematics 2016-09-21 Francesco Rossi , Nastassia Pouradier Duteil , Nir Yakoby , Benedetto Piccoli

The dynamics and motion of multi-ciliated microswimmers with a spherical body and a small number N (with 5 < N < 60) of cilia with length comparable to the body radius, is investigated by mesoscale hydrodynamics simulations. A metachronal…

Soft Condensed Matter · Physics 2024-06-03 Sebastian Rode , Jens Elgeti , Gerhard Gompper

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

Generating high-quality whole-body human object interaction motion sequences is becoming increasingly important in various fields such as animation, VR/AR, and robotics. The main challenge of this task lies in determining the level of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Yonghao Zhang , Qiang He , Yanguang Wan , Yinda Zhang , Xiaoming Deng , Cuixia Ma , Hongan Wang

This article concerns second-order time discretization of subdiffusion equations with time-dependent diffusion coefficients. High-order differentiability and regularity estimates are established for subdiffusion equations with…

Numerical Analysis · Mathematics 2020-06-05 Bangti Jin , Buyang Li , Zhi Zhou

The vibrational properties of a face-centered cubic granular crystal of monodisperse particles are predicted using a discrete model as well as two micropolar models, first the classical Cosserat and second an enhanced Cosserat-type model,…

Soft Condensed Matter · Physics 2016-04-19 A. Merkel , S. Luding

The expansion of biological species in natural environments is usually described as the combined effect of individual spatial dispersal and growth. In the case of aquatic ecosystems flow transport can also be extremely relevant as an extra,…

Biological Physics · Physics 2016-08-30 Francesca Tesser , Jos C. H. Zeegers , Herman J. H. Clercx , Luc Brunsveld , Federico Toschi

An active area of research interest is the inference of ecological models of complex microbial communities. Inferring such ecological models entails understanding the interactions between microbes and how they affect each other's growth.…

Applications · Statistics 2022-10-19 William Krinsman

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein
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