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Graph Nerual Networks (GNNs) are effective models in graph embedding. It extracts shallow features and neighborhood information by aggregating neighbor information to learn the embedding representation of different nodes. However, the local…

Social and Information Networks · Computer Science 2023-12-14 Kejia Zhang

Answering compositional questions that require multiple steps of reasoning against text is challenging, especially when they involve discrete, symbolic operations. Neural module networks (NMNs) learn to parse such questions as executable…

Computation and Language · Computer Science 2020-02-18 Nitish Gupta , Kevin Lin , Dan Roth , Sameer Singh , Matt Gardner

Data mining techniques have been used by researchers for analyzing protein sequences. In protein analysis, especially in protein sequence classification, selection of feature is most important. Popular protein sequence classification…

Databases · Computer Science 2012-11-22 Suprativ Saha , Rituparna Chaki

Protein engineering seeks to identify protein sequences with optimized properties. When guided by machine learning, protein sequence generation methods can draw on prior knowledge and experimental efforts to improve this process. In this…

Quantitative Methods · Quantitative Biology 2021-05-28 Zachary Wu , Kadina E. Johnston , Frances H. Arnold , Kevin K. Yang

We introduce a method to convert an ensemble of sequences of symbols into a weighted directed network whose nodes are motifs, while the directed links and their weights are defined from statistically significant co-occurences of two motifs…

Molecular Networks · Quantitative Biology 2010-10-27 Roberta Sinatra , Daniele Condorelli , Vito Latora

Interaction networks are of central importance in post-genomic molecular biology, with increasing amounts of data becoming available by high-throughput methods. Examples are gene regulatory networks or protein interaction maps. The main…

Statistical Mechanics · Physics 2009-11-10 Johannes Berg , Michael Lässig

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

A machine learning (ML) feature network is a graph that connects ML features in learning tasks based on their similarity. This network representation allows us to view feature vectors as functions on the network. By leveraging function…

Machine Learning · Statistics 2024-01-11 Xinying Mu , Mark Kon

In the age of social computing, finding interesting network patterns or motifs is significant and critical for various areas such as decision intelligence, intrusion detection, medical diagnosis, social network analysis, fake news…

Social and Information Networks · Computer Science 2022-04-07 Shuo Yu , Feng Xia , Yuchen Sun , Tao Tang , Xiaoran Yan , Ivan Lee

Recently, end-to-end memory networks have shown promising results on Question Answering task, which encode the past facts into an explicit memory and perform reasoning ability by making multiple computational steps on the memory. However,…

Information Retrieval · Computer Science 2016-09-29 Jiaming Xu , Jing Shi , Yiqun Yao , Suncong Zheng , Bo Xu , Bo Xu

In this paper, we propose a mechanism for storing complex patterns within a neural network and subsequently recalling them. This model is based on our work published in 2018(Inazawa, 2018), which we have refined and extended in this work.…

Neural and Evolutionary Computing · Computer Science 2025-04-10 Hiroshi Inazawa

Artificial neural networks show promising performance in detecting correlations within data that are associated with specific outcomes. However, the black-box nature of such models can hinder the knowledge advancement in research fields by…

Machine Learning · Computer Science 2023-10-09 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Ensembl's human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal.…

Biomolecules · Quantitative Biology 2010-02-02 W. B. Langdon , Olivia Sanchez Graillet , A. P. Harrison

The 2024 Nobel Prize in Chemistry was awarded in part for protein structure prediction using AlphaFold2, an artificial intelligence/machine learning (AI/ML) model trained on vast amounts of sequence and 3D structure data. AlphaFold2 and…

Biomolecules · Quantitative Biology 2025-04-22 Alexander M. Ille , Emily Anas , Michael B. Mathews , Stephen K. Burley

The graph structure is a commonly used data storage mode, and it turns out that the low-dimensional embedded representation of nodes in the graph is extremely useful in various typical tasks, such as node classification, link prediction ,…

Social and Information Networks · Computer Science 2020-08-03 Xing Li , Wei Wei , Xiangnan Feng , Xue Liu , Zhiming Zheng

Deep neural networks have shown superior performance in many regimes to remember familiar patterns with large amounts of data. However, the standard supervised deep learning paradigm is still limited when facing the need to learn new…

Machine Learning · Computer Science 2018-11-16 Jing Shi , Jiaming Xu , Yiqun Yao , Bo Xu

Predicting protein properties such as solvent accessibility and secondary structure from its primary amino acid sequence is an important task in bioinformatics. Recently, a few deep learning models have surpassed the traditional window…

Machine Learning · Computer Science 2016-05-11 Zeming Lin , Jack Lanchantin , Yanjun Qi

Non protein coding regions of the human genome contain many complex patterns which regulate the cellular activity. Studying the human genome is limited by the lack of understanding of its features and their complex interactions. However,…

Genomics · Quantitative Biology 2017-08-15 Kerim Arioglu , Umut Eser

Recurrent Neural Networks (RNN) have obtained excellent result in many natural language processing (NLP) tasks. However, understanding and interpreting the source of this success remains a challenge. In this paper, we propose Recurrent…

Computation and Language · Computer Science 2016-04-25 Ke Tran , Arianna Bisazza , Christof Monz

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror