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We propose a formal mathematical model for sparse representations and active dendrites in neocortex. Our model is inspired by recent experimental findings on active dendritic processing and NMDA spikes in pyramidal neurons. These…

Neurons and Cognition · Quantitative Biology 2016-05-16 Subutai Ahmad , Jeff Hawkins

Small target motion detection is critical for insects to search for and track mates or prey which always appear as small dim speckles in the visual field. A class of specific neurons, called small target motion detectors (STMDs), has been…

Neural and Evolutionary Computing · Computer Science 2018-07-12 Hongxin Wang , Jigen Peng , Shigang Yue

In this paper, we present a neuro-inspired approach to reservoir computing (RC) in which a network of in vitro cultured cortical neurons serves as the physical reservoir. Rather than relying on artificial recurrent models to approximate…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Luca Ciampi , Ludovico Iannello , Fabrizio Tonelli , Gabriele Lagani , Angelo Di Garbo , Federico Cremisi , Giuseppe Amato

A major goal of neuroscience is to understand brain computations during visual processing in naturalistic settings. A dominant approach is to use image-computable deep neural networks trained with different task objectives as a basis for…

Neurons and Cognition · Quantitative Biology 2026-02-06 Hossein Adeli , Sun Minni , Nikolaus Kriegeskorte

Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Shir Gur , Lior Wolf , Lior Golgher , Pablo Blinder

Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Large-scale functional networks have been extensively studied using resting state functional magnetic resonance imaging. However, the pattern, organization, and function of fine-scale network activity remain largely unknown. Here we…

Neurons and Cognition · Quantitative Biology 2017-03-01 Kun-Han Lu , Jun Young Jeong , Haiguang Wen , Zhongming Liu

Neural encoding models aim to predict fMRI-measured brain responses to natural images. fMRI data is acquired as a 3D volume of voxels, where each voxel has a defined spatial location in the brain. However, conventional encoding models often…

Neurons and Cognition · Quantitative Biology 2026-02-11 Haomiao Chen , Keith W Jamison , Mert R. Sabuncu , Amy Kuceyeski

Our visual system is astonishingly efficient at detecting moving objects. This process is mediated by the neurons which connect the primary visual cortex (V1) to the middle temporal (MT) area. Interestingly, since Kuffler's pioneering…

Neurons and Cognition · Quantitative Biology 2014-01-23 Stephen G. Odaibo

Biological systems leverage top-down feedback for visual processing, yet most artificial vision models succeed in image classification using purely feedforward or recurrent architectures, calling into question the functional significance of…

Neurons and Cognition · Quantitative Biology 2025-08-12 Antonino Greco , Marco D'Alessandro , Karl J. Friston , Giovanni Pezzulo , Markus Siegel

Purpose: To enable rigid-body motion tolerant parallel volumetric magnetic resonance imaging by retrospective head motion correction on a variety of spatio-temporal scales and imaging sequences. Theory and methods: Tolerance against…

Deep convolutional neural networks (CNNs) trained on objects and scenes have shown intriguing ability to predict some response properties of visual cortical neurons. However, the factors and computations that give rise to such ability, and…

Neurons and Cognition · Quantitative Biology 2018-06-11 Md Nasir Uddin Laskar , Luis G Sanchez Giraldo , Odelia Schwartz

Identifying cell types and understanding their functional properties is crucial for unraveling the mechanisms underlying perception and cognition. In the retina, functional types can be identified by carefully selected stimuli, but this…

Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

We propose a multiscale spatio-temporal graph neural network (MST-GNN) to predict the future 3D skeleton-based human poses in an action-category-agnostic manner. The core of MST-GNN is a multiscale spatio-temporal graph that explicitly…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Maosen Li , Siheng Chen , Yangheng Zhao , Ya Zhang , Yanfeng Wang , Qi Tian

Given a visual history, multiple future outcomes for a video scene are equally probable, in other words, the distribution of future outcomes has multiple modes. Multimodality is notoriously hard to handle by standard regressors or…

Computer Vision and Pattern Recognition · Computer Science 2017-05-08 Katerina Fragkiadaki , Jonathan Huang , Alex Alemi , Sudheendra Vijayanarasimhan , Susanna Ricco , Rahul Sukthankar

Humans effortlessly navigate the dynamic visual world, yet deep neural networks (DNNs), despite excelling at many visual tasks, are surprisingly vulnerable to minor image perturbations. Past theories suggest that human visual robustness…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Zhenan Shao , Linjian Ma , Yiqing Zhou , Yibo Jacky Zhang , Sanmi Koyejo , Bo Li , Diane M. Beck

To evaluate the nature of the neural code in the cerebral cortex, we have used a combination of theory and experiment to assess how information is represented in a realistic cortical population response. We have shown how a sensory stimulus…

Neurons and Cognition · Quantitative Biology 2008-03-28 L. C. Osborne , S. E. Palmer , S. G. Lisberger , W. Bialek

Recurrent Neural Networks (RNNs) are popular models of brain function. The typical training strategy is to adjust their input-output behavior so that it matches that of the biological circuit of interest. Even though this strategy ensures…

Neurons and Cognition · Quantitative Biology 2020-11-09 Alessandro Salatiello , Martin A. Giese

A major goal of computational neuroscience has been to explain how the primate ventral visual stream (VVS) transforms visual input into temporally evolving neural representations that support robust visual perception. Historically, most…

Neurons and Cognition · Quantitative Biology 2026-01-21 Matteo Dunnhofer , Maren Wehrheim , Hamidreza Ramezanpour , Sabine Muzellec , Kohitij Kar