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Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Purpose: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in-vivo imaging with confocal laser microscopy has…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Nils Gessert , Marcel Bengs , Lukas Wittig , Daniel Drömann , Tobias Keck , Alexander Schlaefer , David B. Ellebrecht

Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Jiaqi Lv , Stefan S Antonowicz , Shan E Ahmed Raza

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu

Colorectal cancer is one of the most common cancers worldwide, so early pathological examination is very important. However, it is time-consuming and labor-intensive to identify the number and type of cells on H&E images in clinical.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Chia-Yen Lee , Hsiang-Chin Chien , Ching-Ping Wang , Hong Yen , Kai-Wen Zhen , Hong-Kun Lin

Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

Computer Vision and Pattern Recognition · Computer Science 2018-03-07 Ruqayya Awan , Navid Alemi Koohbanani , Muhammad Shaban , Anna Lisowska , Nasir Rajpoot

In this paper we introduce a new problem within the growing literature of interpretability for convolution neural networks (CNNs). While previous work has focused on the question of how to visually interpret CNNs, we ask what it is that we…

Computer Vision and Pattern Recognition · Computer Science 2022-01-03 Sílvia Casacuberta , Esra Suel , Seth Flaxman

In recent years, advances in the development of whole-slide images have laid a foundation for the utilization of digital images in pathology. With the assistance of computer images analysis that automatically identifies tissue or cell…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jun Wang , Qianying Liu , Haotian Xie , Zhaogang Yang , Hefeng Zhou

Convolutional Neural Networks have shown promising effectiveness in identifying different types of cancer from radiographs. However, the opaque nature of CNNs makes it difficult to fully understand the way they operate, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Michael Okonoda , Eder Martinez , Abhilekha Dalal , Lior Shamir

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

Image and Video Processing · Electrical Eng. & Systems 2026-05-14 Md Fahimul Kabir Chowdhury , Jannatul Ferdous

Computer Tomography (CT) images have become quite important to diagnose diseases. CT scan slice contains a vast amount of data that may not be properly examined with the requisite precision and speed using normal visual inspection. A…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Md Moniruzzaman Emon , Tareque Rahman Ornob , Moqsadur Rahman

FT-Raman spectroscopy was employed to study (in-vitro) non-altered human colorectal tissues aiming evaluate their spectral differences. The samples were collected from 39 patients, adding 144 spectra. The results enable one estabilish 3…

Tissues and Organs · Quantitative Biology 2007-05-23 P. O. Andrade , R. A. Bitar , K. Yassoyama , H. Martinho , A. M. E. Santo , P. M. Bruno , A. A. Martin

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

Traditional breast cancer image classification methods require manual extraction of features from medical images, which not only require professional medical knowledge, but also have problems such as time-consuming and labor-intensive and…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Mengfan Li

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

Convolutional neural networks (CNNs) have achieved state-of-the-art results on many visual recognition tasks. However, current CNN models still exhibit a poor ability to be invariant to spatial transformations of images. Intuitively, with…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Xu Shen , Xinmei Tian , Anfeng He , Shaoyan Sun , Dacheng Tao

Convolutional Neural Networks can be designed with different levels of complexity depending upon the task at hand. This paper analyzes the effect of dimensional changes to the CNN architecture on its performance on the task of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shreyas Rajesh Labhsetwar , Alistair Michael Baretto , Raj Sunil Salvi , Piyush Arvind Kolte , Veerasai Subramaniam Venkatesh

Deep learning algorithms offer a powerful means to automatically analyze the content of medical images. However, many biological samples of interest are primarily transparent to visible light and contain features that are difficult to…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Roarke Horstmeyer , Richard Y. Chen , Barbara Kappes , Benjamin Judkewitz

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Breast cancer is the most common cancer in women. Classification of cancer/non-cancer patients with clinical records requires high sensitivity and specificity for an acceptable diagnosis test. The state-of-the-art classification model -…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Anuraganand Sharma , Dinesh Kumar