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The Quadrant-Slope Index (QSI) method was created in order to detect subtle patterns of organization in tumor images that have metaplastic elements, such as streams of spindle cells [1]. However, metaplastic tumors also have nuclei that may…

Tissues and Organs · Quantitative Biology 2017-04-26 David H. Nguyen

Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Ziheng Zhang , Zihan Li , Dandan Shan , Yuehui Qiu , Qingqi Hong , Qingqiang Wu

Early and correct diagnosis is a very important aspect of cancer treatment. Detection of tumour in Computed Tomography scan is a tedious and tricky task which requires expert knowledge and a lot of human working hours. As small human error…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Devesh Walawalkar

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Automatic segmentation of microscopy images is an important task in medical image processing and analysis. Nucleus detection is an important example of this task. Mask-RCNN is a recently proposed state-of-the-art algorithm for object…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Jeremiah W. Johnson

Mucous glands lesions analysis and assessing of malignant potential of colon polyps are very important tasks of surgical pathology. However, differential diagnosis of colon polyps often seems impossible by classical methods and it is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 A. Khvostikov , A. Krylov , O. Kharlova , N. Oleynikova , I. Mikhailov , P. Malkov

Manual preparation of tissue slices for microscopy imaging can introduce tissue tears and overlaps. Typically, further digital processing algorithms such as registration and 3D reconstruction from tissue image stacks cannot handle images…

Computer Vision and Pattern Recognition · Computer Science 2019-05-23 Zahra Montazeri , Gopi M

Automatic segmentation of the placenta in fetal ultrasound (US) is challenging due to the (i) high diversity of placenta appearance, (ii) the restricted quality in US resulting in highly variable reference annotations, and (iii) the limited…

In industrial defect segmentation tasks, while pixel accuracy and Intersection over Union (IoU) are commonly employed metrics to assess segmentation performance, the output consistency (also referred to equivalence) of the model is often…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zhen Qu , Xian Tao , Fei Shen , Zhengtao Zhang , Tao Li

Accurate segmentation of polyps from colonoscopy images is crucial for the early diagnosis and treatment of colorectal cancer. Most existing deep learning-based polyp segmentation methods adopt an Encoder-Decoder architecture, and some…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Desheng Li , Chaoliang Liu , Zhiyong Xiao

Instance segmentation of overlapping objects in biomedical images remains a largely unsolved problem. We take up this challenge and present MultiStar, an extension to the popular instance segmentation method StarDist. The key novelty of our…

Computer Vision and Pattern Recognition · Computer Science 2021-01-15 Florin C. Walter , Sebastian Damrich , Fred A. Hamprecht

With the rapid advancement of deep learning, computational pathology has made significant progress in cancer diagnosis and subtyping. Tissue segmentation is a core challenge, essential for prognosis and treatment decisions. Weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Hongyi Wu , Hong Zhang

Cervical cancer is a leading malignancy in female reproductive system. While AI-assisted cytology offers a cost-effective and non-invasive screening solution, current systems struggle with generalizability in complex clinical scenarios. To…

Automatic organ segmentation is an important prerequisite for many computer-aided diagnosis systems. The high anatomical variability of organs in the abdomen, such as the pancreas, prevents many segmentation methods from achieving high…

Computer Vision and Pattern Recognition · Computer Science 2015-09-17 Holger R. Roth , Amal Farag , Le Lu , Evrim B. Turkbey , Ronald M. Summers

Image segmentation is a fundamental problem in medical image analysis. In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Ling Zhang , Vissagan Gopalakrishnan , Le Lu , Ronald M. Summers , Joel Moss , Jianhua Yao

Curvilinear structure segmentation is important in medical imaging, quantifying structures such as vessels, airways, neurons, or organ boundaries in 2D slices. Segmentation via pixel-wise classification often fails to capture the small and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Manxi Lin , Zahra Bashir , Martin Grønnebæk Tolsgaard , Anders Nymark Christensen , Aasa Feragen

Cell detection is a fundamental task in computational pathology that can be used for extracting high-level medical information from whole-slide images. For accurate cell detection, pathologists often zoom out to understand the tissue-level…

Several image pattern recognition tasks rely on superpixel generation as a fundamental step. Image analysis based on superpixels facilitates domain-specific applications, also speeding up the overall processing time of the task. Recent…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Marcelo Santos , Luciano Oliveira

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-15 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Maode Lai , Eric I-Chao Chang

Automatic tissue segmentation and nuclei detection is an important task in pathology, aiding in biomarker extraction and discovery. The panoptic segmentation of nuclei and tissue in advanced melanoma (PUMA) challenge aims to improve tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Negar Shahamiri , Moritz Rempe , Lukas Heine , Jens Kleesiek , Fabian Hörst