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Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences from them construct a value that, in expectation, is additive under a stochastic…

Populations and Evolution · Quantitative Biology 2008-08-21 Mike Steel

We describe algorithms for finding the regression of t, a sequence of values, to the closest sequence s by mean squared error, so that s is always increasing (isotonicity) and so the values of two consecutive points do not increase by too…

Data Structures and Algorithms · Computer Science 2009-12-31 Pankaj K. Agarwal , Jeff M. Phillips , Bardia Sadri

Tree representations of (sets of) symmetric binary relations, or equivalently edge-colored undirected graphs, are of central interest, e.g.\ in phylogenomics. In this context symbolic ultrametrics play a crucial role. Symbolic ultrametrics…

Discrete Mathematics · Computer Science 2015-09-18 Marc Hellmuth , Nicolas Wieseke

We study the geometry of metrics and convexity structures on the space of phylogenetic trees, which is here realized as the tropical linear space of all \ ultrametrics. The ${\rm CAT}(0)$-metric of Billera-Holmes-Vogtman arises from the…

Metric Geometry · Mathematics 2018-02-19 Bo Lin , Bernd Sturmfels , Xiaoxian Tang , Ruriko Yoshida

Semidirected networks have received interest in evolutionary biology as the appropriate generalization of unrooted trees to networks, in which some but not all edges are directed. Yet these networks lack proper theoretical study. We define…

Combinatorics · Mathematics 2024-10-14 Michael Maxfield , Jingcheng Xu , Cécile Ané

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

We address the problem of merging graph and feature-space information while learning a metric from structured data. Existing algorithms tackle the problem in an asymmetric way, by either extracting vectorized summaries of the graph…

Machine Learning · Computer Science 2020-02-17 Nicolo Colombo

The decomposition of a density function on a domain into a minimal sum of unimodal components is a fundamental problem in statistics, leading to the topological invariant of unimodal category of a density. This paper gives an efficient…

Algebraic Topology · Mathematics 2018-06-27 Yuliy Baryshnikov , Robert Ghrist

Trajectories represent the mobility of moving objects and thus is of great value in data mining applications. However, trajectory data is enormous in volume, so it is expensive to store and process the raw data directly. Trajectories are…

Databases · Computer Science 2020-10-20 Yunheng Han , Hanan Samet

Phylogenetics begins with reconstructing biological family trees from genetic data. Since Nature is not limited to tree-like histories, we use networks to organize our data, and have discovered new polytopes, metric spaces, and simplicial…

Combinatorics · Mathematics 2019-05-28 Satyan Devadoss , Cassandra Durell , Stefan Forcey

Starting with a similarity function between objects, it is possible to define a distance metric on pairs of objects, and more generally on probability distributions over them. These distance metrics have a deep basis in functional analysis,…

Computational Geometry · Computer Science 2011-03-15 Sarang Joshi , Raj Varma Kommaraju , Jeff M. Phillips , Suresh Venkatasubramanian

The goal of this paper is to study the similarity between sequences using a distance between the \emph{context} trees associated to the sequences. These trees are defined in the framework of \emph{Sparse Probabilistic Suffix Trees} (SPST),…

Applications · Statistics 2008-04-29 Florencia Leonardi , Sergio R. Matioli , Hugo A. Armelin , Antonio Galves

This work presents novel algorithms for learning Bayesian network structures with bounded treewidth. Both exact and approximate methods are developed. The exact method combines mixed-integer linear programming formulations for structure…

Artificial Intelligence · Computer Science 2014-06-09 Siqi Nie , Denis Deratani Maua , Cassio Polpo de Campos , Qiang Ji

In the longest plane spanning tree problem, we are given a finite planar point set $\mathcal{P}$, and our task is to find a plane (i.e., noncrossing) spanning tree for $\mathcal{P}$ with maximum total Euclidean edge length. Despite more…

Computational Geometry · Computer Science 2024-05-02 Sergio Cabello , Michael Hoffmann , Katharina Klost , Wolfgang Mulzer , Josef Tkadlec

We study the problem of learning a latent tree graphical model where samples are available only from a subset of variables. We propose two consistent and computationally efficient algorithms for learning minimal latent trees, that is, trees…

Machine Learning · Statistics 2010-09-15 Myung Jin Choi , Vincent Y. F. Tan , Animashree Anandkumar , Alan S. Willsky

When estimating a phylogeny from a multiple sequence alignment, researchers often assume the absence of recombination. However, if recombination is present, then tree estimation and all downstream analyses will be impacted, because…

The contributions of the paper span theoretical and implementational results. First, we prove that Kd-trees can be extended to spaces in which the distance is measured with an arbitrary Bregman divergence. Perhaps surprisingly, this shows…

Computational Geometry · Computer Science 2025-02-20 Tuyen Pham , Hubert Wagner

In this paper we show how to recover a spectral approximations to broad classes of structured matrices using only a polylogarithmic number of adaptive linear measurements to either the matrix or its inverse. Leveraging this result we obtain…

Data Structures and Algorithms · Computer Science 2018-12-18 Arun Jambulapati , Kirankumar Shiragur , Aaron Sidford

The goal of this work is to decompose random populations with a genealogy in subfamilies of a given degree of kinship and to obtain a notion of infinitely divisible genealogies. We model the genealogical structure of a population by…

Probability · Mathematics 2019-04-09 Patrick Gloede , Andreas Greven , Thomas Rippl

We devise a generalization of tree approximation that generates conforming meshes, i.e., meshes with a particular structure like edge-to-edge triangulations. A key feature of this generalization is that the choices of the cells to be…

Numerical Analysis · Mathematics 2023-01-26 Peter Binev , Francesca Fierro , Andreas Veeser
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