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Related papers: FMRI Clustering and False Positive Rates

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Recent reports of inflated false positive rates (FPRs) in FMRI group analysis tools by Eklund et al. (2016) have become a large topic within (and outside) neuroimaging. They concluded that: existing parametric methods for determining…

Quantitative Methods · Quantitative Biology 2017-02-17 Robert W. Cox , Gang Chen , Daniel R. Glen , Richard C. Reynolds , Paul A. Taylor

Methodological research rarely generates a broad interest, yet our work on the validity of cluster inference methods for functional magnetic resonance imaging (fMRI) created intense discussion on both the minutia of our approach and its…

Applications · Statistics 2019-01-03 Anders Eklund , Hans Knutsson , Thomas E Nichols

A recent Editorial by Slotnick (2017) reconsiders the findings of our paper on the accuracy of false positive rate control with cluster inference in fMRI (Eklund et al, 2016), in particular criticising our use of resting state fMRI data as…

Applications · Statistics 2017-01-19 Thomas E. Nichols , Anders Eklund , Hans Knutsson

We are glad that our paper has generated intense discussions in the fMRI field, on how to analyze fMRI data and how to correct for multiple comparisons. The goal of the paper was not to disparage any specific fMRI software, but to point out…

Applications · Statistics 2017-05-31 Anders Eklund , Thomas Nichols , Hans Knutsson

Given the recent controversies in some neuroimaging statistical methods, we compare the most frequently used functional Magnetic Resonance Imaging (fMRI) analysis packages: AFNI, FSL and SPM, with regard to temporal autocorrelation…

Quantitative Methods · Quantitative Biology 2019-04-09 Wiktor Olszowy , John Aston , Catarina Rua , Guy B. Williams

The most widely used task fMRI analyses use parametric methods that depend on a variety of assumptions. While individual aspects of these fMRI models have been evaluated, they have not been evaluated in a comprehensive manner with empirical…

Applications · Statistics 2016-07-14 Anders Eklund , Thomas Nichols , Hans Knutsson

We consider the problem of estimating the false-/ true-positive-rate (FPR/TPR) for a binary classification model when there are incorrect labels (label noise) in the validation set. Our motivating application is fraud prevention where…

Machine Learning · Computer Science 2023-08-08 Justin Tittelfitz

In their recent "Cluster Failure" paper, Eklund and colleagues cast doubt on the accuracy of a widely used statistical test in functional neuroimaging. Here, we leverage nonparametric methods that control the false discovery rate to offer…

Applications · Statistics 2016-08-04 Daniel Kessler , Michael Angstadt , Chandra Sripada

Clustering is a central tool in biomedical research for discovering heterogeneous patient subpopulations, where group boundaries are often diffuse rather than sharply separated. Traditional methods produce hard partitions, whereas soft…

Methodology · Statistics 2026-01-07 Qiuyi Wu , Zihan Zhu , Anru R. Zhang

This paper provides a theoretical explanation on the clustering aspect of nonnegative matrix factorization (NMF). We prove that even without imposing orthogonality nor sparsity constraint on the basis and/or coefficient matrix, NMF still…

Machine Learning · Computer Science 2010-06-15 Andri Mirzal , Masashi Furukawa

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Fast Radio Bursts (FRBs) are millisecond-duration radio transients of extragalactic origin. Classifying repeating FRBs is essential for understanding their emission mechanisms, but remains challenging due to their short durations, high…

High Energy Astrophysical Phenomena · Physics 2026-01-23 An-Chieh Hsu , Tetsuya Hashimoto , Tomotsugu Goto , Tomoki Wada , Bjorn Jasper Raquel

In this paper, we present a framework for assessing the effect of non-stationary Gaussian noise and radio frequency interference (RFI) on the signal to noise ratio, the number of false positives detected per true positive and the…

Instrumentation and Methods for Astrophysics · Physics 2017-04-19 E. van Heerden , A. Karastergiou , S. J. Roberts

The Adjusted Rand Index (ARI) is a widely used method for comparing hard clusterings, but requires a choice of random model that is often left implicit. Several recent works have extended the Rand Index to fuzzy clusterings, but the…

Machine Learning · Statistics 2025-02-17 Ryan DeWolfe , Jeffery L. Andrews

There is no, nor will there ever be, single best clustering algorithm. Nevertheless, we would still like to be able to distinguish between methods that work well on certain task types and those that systematically underperform. Clustering…

Machine Learning · Computer Science 2025-10-16 Marek Gagolewski

The detection of malware is a critical task for the protection of computing environments. This task often requires extremely low false positive rates (FPR) of 0.01% or even lower, for which modern machine learning has no readily available…

Machine Learning · Computer Science 2021-09-07 Andre T. Nguyen , Edward Raff , Charles Nicholas , James Holt

The clustering task consists in partitioning elements of a sample into homogeneous groups. Most datasets contain individuals that are ambiguous and intrinsically difficult to attribute to one or another cluster. However, in practical…

Statistics Theory · Mathematics 2023-10-26 Ariane Marandon , Tabea Rebafka , Etienne Roquain , Nataliya Sokolovska

In recent years, there has been a surge in effort to formalize notions of fairness in machine learning. We focus on centroid clustering--one of the fundamental tasks in unsupervised machine learning. We propose a new axiom ``proportionally…

Machine Learning · Computer Science 2024-11-05 Haris Aziz , Barton E. Lee , Sean Morota Chu , Jeremy Vollen

Demographic bias is a significant challenge in practical face recognition systems. Existing methods heavily rely on accurate demographic annotations. However, such annotations are usually unavailable in real scenarios. Moreover, these…

Computer Vision and Pattern Recognition · Computer Science 2021-06-11 Xingkun Xu , Yuge Huang , Pengcheng Shen , Shaoxin Li , Jilin Li , Feiyue Huang , Yong Li , Zhen Cui

Classification is a fundamental task in many applications on which data-driven methods have shown outstanding performances. However, it is challenging to determine whether such methods have achieved the optimal performance. This is mainly…

Machine Learning · Computer Science 2024-01-30 Minoh Jeong , Martina Cardone , Alex Dytso
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