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Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

Brain organoids recapitulate a number of brain properties, including neuronal diversity. However, do they recapitulate brain structure? Using a hydrodynamic description for cell nuclei as particles interacting initially via an effective,…

Soft Condensed Matter · Physics 2021-12-15 Ahmad Borzou , J. M. Schwarz

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

Soft Condensed Matter · Physics 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

LLMs are trained once, then deployed into a world that never stops changing. External memory compensates for this, but most systems manage it explicitly rather than letting it adapt on its own. Biological memory works differently: coupled…

Machine Learning · Computer Science 2026-05-08 Andreas Pattichis , Constantine Dovrolis

Liquid crystal elastomers represent a novel class of programmable shape-transforming materials whose shape change trajectory is encoded in the material's nematic director field. Using three-dimensional nonlinear finite element…

Soft Condensed Matter · Physics 2016-02-16 Andrew Konya , Vianney Gimenez-Pinto , Robin Selinger

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

Soft Condensed Matter · Physics 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

The transport on top of a periodic two-dimensional hexagonal magnetic pattern of (i) a single macroscopic steel sphere, (ii) a doublet of wax/magnetite composite spheres, and (iii) an immiscible mixture of ferrofluid droplets with a…

We investigate the equilibrium morphology of a finite volume of liquid placed on two parallel rigid fibers of different radii. As observed for identical radii fibers, the liquid is either in a column morphology or adopts a drop shape…

Soft Condensed Matter · Physics 2015-04-23 Alban Sauret , François Boulogne , David Cébron , Emilie Dressaire , Howard A. Stone

In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…

Tissues and Organs · Quantitative Biology 2017-09-08 Matthias Merkel , Raphaël Etournay , Marko Popović , Guillaume Salbreux , Suzanne Eaton , Frank Jülicher

We use numerical simulations to show how noninteracting hard particles binding to a deformable elastic shell may self-assemble into a variety of linear patterns. This is a result of the nontrivial elastic response to deformations of shells.…

Soft Condensed Matter · Physics 2011-02-25 Andela Šarić , Angelo Cacciuto

We demonstrate that the active thermocapillary stresses induced by multiple microbubbles offer simple routes to directed self-assembly and complex but controllable micromanipulation of mesoscopic colloidal particles embedded in a liquid.…

Fluid Dynamics · Physics 2019-03-26 Subhrokoli Ghosh , Aritra Biswas , Basudev Roy , Ayan Banerjee

Reinforced elastic sheets surround us in daily life, from concrete shell buildings to biological structures such as the arthropod exoskeleton or the venation network of dicotyledonous plant leaves. Natural structures are often highly…

Biological Physics · Physics 2021-01-27 Henrik Ronellenfitsch

Collective guidance of out-of-equilibrium systems without using external fields is a challenge of paramount importance in active matter, ranging from bacterial colonies to swarms of self-propelled particles. Designing strategies to guide…

We present a two-scale topology optimization framework for the design of macroscopic bodies with an optimized elastic response, which is achieved by means of a spatially-variant cellular architecture on the microscale. The chosen spinodoid…

Computational Engineering, Finance, and Science · Computer Science 2021-05-21 Li Zheng , Siddhant Kumar , Dennis M. Kochmann

Spatially confined rigid membranes reorganize their morphology in response to the imposed constraints. A crumpled elastic sheet presents a complex pattern of random folds focusing the deformation energy while compressing a membrane resting…

The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and…

Biological Physics · Physics 2022-06-07 Jean-François Louf , Felix Kratz , Sujit S. Datta

The potential of memristive devices is often seeing in implementing neuromorphic architectures for achieving brain-like computation. However, the designing procedures do not allow for extended manipulation of the material, unlike CMOS…

Emerging Technologies · Computer Science 2016-04-25 Shari Lim Wei , Eleni Vasilaki , Ali Khiat , Iulia Salaoru , Radu Berdan , Themistoklis Prodromakis

We study the morphology of Eulerian vortical structures and their interaction with density interfaces in increasingly turbulent stably-stratified shear layers. We analyse the three-dimensional, simultaneous velocity and density fields…

Fluid Dynamics · Physics 2022-09-07 Xianyang Jiang , Adrien Lefauve , Stuart B. Dalziel , P. F. Linden

Soft-granular media, such as dense emulsions, foams or tissues, exhibit either fluid- or solid-like properties depending on the applied external stresses. Whereas bulk rheology of such materials has been thoroughly investigated, the…

Soft Condensed Matter · Physics 2024-07-04 Michal Bogdan , Jesus Pineda , Mihir Durve , Leon Jurkiewicz , Sauro Succi , Giovanni Volpe , Jan Guzowski

Transitions from quiescence to collective migration in epithelia underlie wound healing and cancer invasion, yet their physical origin remains poorly understood. Here we show that quiescent epithelial monolayers store spatially contractile…

Soft Condensed Matter · Physics 2026-05-25 Richard Ho , Anna Lång , Emma Lång , Stig Ove Bøe , Luiza Angheluta
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