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While the dynamics of a fully flexible polymer ejecting a capsid through a nanopore has been extensively studied, the ejection dynamics of semiflexible polymers has not been properly characterized. Here we report results from simulations of…

Biological Physics · Physics 2017-11-08 Riku P. Linna , Pauli M. Suhonen , Joonas Piili

Polymer ejection from a capsid through a nanoscale pore is an important biological process with relevance to modern biotechnology. Here, we study generic capsid ejection using Langevin dynamics. We show that even when the ejection takes…

Biological Physics · Physics 2014-05-09 R. P. Linna , J. E. Moisio , P. M. Suhonen , K. Kaski

We examine the ejection of an initially strongly confined flexible polymer from a spherical capsid through a nanoscale pore. We use molecular dynamics for unprecedentedly high initial monomer densities. We show that the time for an…

Biological Physics · Physics 2016-01-06 J. Piili , R. P. Linna

Langevin dynamics simulations are performed to investigate ejection dynamics of spherically confined flexible polymers through a pore. By varying the chain length $N$ and the initial volume fraction $\phi_0$ of the monomers, two scaling…

Soft Condensed Matter · Physics 2020-01-29 Hao-Chun Huang , Pai-Yi Hsiao

We investigate the ejection dynamics of a ring polymer out of a cylindrical nanochannel using both theoretical analysis and three dimensional Langevin dynamics simulations. The ejection dynamics for ring polymers shows two regimes like for…

Soft Condensed Matter · Physics 2011-12-19 Junfang Sheng , Kaifu Luo

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer…

Soft Condensed Matter · Physics 2024-07-29 Gokul Upadhyay , Rajeev Kapri , Anil Kumar Dasanna , Abhishek Chaudhuri

The theory of the dynamics of polymers in solution is developed coming from the hydrodynamic theory of the Brownian motion (BM) and the Rouse-Zimm (RZ) model. It is shown that the time correlation functions describing the polymer motion…

Soft Condensed Matter · Physics 2007-05-23 V. Lisy , J. Tothova , B. Brutovsky , A. V Zatovsky

We study the rotational dynamics of a flexible polymer initially wrapped around a rigid rod and unwinding from it. This dynamics is of interest in several problems in biology and constitutes a fundamental instance of polymer relaxation from…

Soft Condensed Matter · Physics 2014-07-29 Jean-Charles Walter , Marco Baiesi , Enrico Carlon , Helmut Schiessel

We investigate the effect of hydrodynamic interactions on the non-equilibrium drift dynamics of an ideal flexible polymer pulled by a constant force applied at one end of the polymer using the perturbation theory and the renormalization…

Statistical Mechanics · Physics 2009-11-13 Semjon Stepanow , Norio Kikuchi

The hydrodynamic radius of a polymer chain, obtained using Brownian dynamics simulations of the continuum Edwards model, is found to obey a crossover in the excluded volume parameter z, which is significantly different from that observed…

Soft Condensed Matter · Physics 2020-07-03 P. Sunthar , J. Ravi Prakash

Translocation of a polymer out of curved surface or membrane is studied via mean first passage time approach. Membrane curvature gives rise to a constraint on polymer conformation, which effectively drives the polymer to the outside of…

Soft Condensed Matter · Physics 2009-10-31 Pyeong Jun Park , Wokyung Sung

We study a model of rolling particles subject to stochastic fluctuations, which may be relevant in systems of nano- or micro-scale particles where rolling is an approximation for strong static friction. We consider the simplest possible…

Mathematical Physics · Physics 2016-10-04 Miranda Holmes-Cerfon

The dynamics of flexible polymers in dilute solutions is studied taking into account the hydrodynamic memory, as a consequence of fluid inertia. As distinct from the Rouse-Zimm (RZ) theory, the Boussinesq friction force acts on the monomers…

Soft Condensed Matter · Physics 2009-11-10 V. Lisy , J. Tothova , A. V. Zatovsky

We consider the statics and dynamics of a flexible polymer confined between parallel plates both in the presence and absence of hydrodynamic interactions. The hydrodynamic interactions are described at the level of the fluctuating,…

Soft Condensed Matter · Physics 2012-11-01 Santtu T. T. Ollila , Colin Denniston , Mikko Karttunen , Tapio Ala-Nissila

Polymer ejection from nano-confinement has been of interest due to its relation to various fundamental sciences and applications. However, the ejection dynamics of a polymer with different persistence lengths from confinement through a…

Soft Condensed Matter · Physics 2023-06-13 Farzaneh Moazemi , Samaneh Ghanbari-Kashan , Narges Nikoofard

We investigate the driven polymer translocation through a nanometer-scale pore in the presence and absence of hydrodynamics both in good and bad solvent. We present our results on tension propagating along the polymer segment on the…

Biological Physics · Physics 2016-09-21 Jaakko E. Moisio , Joonas Piili , Riku P. Linna

Experimental investigations of the exit dynamics of a horizontal cylindrical object were performed in water and silicone oil (50 cSt). The fully immersed cylinder was initially at rest in a still fluid tank before being pushed (or pulled…

Hydrodynamic forces may significantly affect the motion of polymers. In sheet-like cavities, such as the cell's cytoplasm and microfluidic channels, the hydrodynamic forces are long-range. It is therefore expected that that hydrodynamic…

Soft Condensed Matter · Physics 2010-08-04 Tsvi Tlusty

This paper presents a theoretical analysis of the closure kinetics of a polymer with hydrodynamic interactions. This analysis, which takes into account the non-Markovian dynamics of the end-to-end vector and relies on the preaveraging of…

The rate of escape of polymers from a two-dimensionally confining potential well has been evaluated using self-avoiding as well as ideal chain representations of varying length, up to 80 beads. Long timescale Langevin trajectories were…

Soft Condensed Matter · Physics 2015-03-27 Harri Mökkönen , Timo Ikonen , Tapio Ala-Nissila , Hannes Jónsson
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