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Providing an analytical treatment to the stochastic feature of neurons' dynamics is one of the current biggest challenges in mathematical biology. The noisy leaky integrate-and-fire model and its associated Fokker-Planck equation are…

Neurons and Cognition · Quantitative Biology 2015-12-14 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

In this paper, we propose a shot noise-based leaky integrated and firing neuron model and provide a detailed analysis of the performance of this model compared to the traditional diffusion approximated model. In theoretical neuroscience,…

Neurons and Cognition · Quantitative Biology 2018-07-05 Zihao Xu

Stochastic integrate-and-fire (IF) neuron models have found widespread applications in computational neuroscience. Here we present results on the white-noise-driven perfect, leaky, and quadratic IF models, focusing on the spectral…

Neurons and Cognition · Quantitative Biology 2015-05-14 Rafael D. Vilela , Benjamin Lindner

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

Analysis of PDEs · Mathematics 2020-11-11 Grégory Dumont , Pierre Gabriel

We present an approximate analytical expression for the escape rate of time-dependent driven stochastic processes with an absorbing boundary such as the driven leaky integrate-and-fire model for neural spiking. The novel approximation is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Michael Schindler , Peter Talkner , Peter Hänggi

Identifying the right tools to express the stochastic aspects of neural activity has proven to be one of the biggest challenges in computational neuroscience. Even if there is no definitive answer to this issue, the most common procedure to…

Neurons and Cognition · Quantitative Biology 2016-02-12 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

The seemingly stochastic transient dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference. In vitro neurons, on the other hand, exhibit a highly deterministic…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

The response properties of excitable systems driven by colored noise are of great interest, but are usually mathematically only accessible via approximations. For this reason, dichotomous noise, a rare example of a colored noise leading…

Biological Physics · Physics 2017-02-01 Felix Droste , Benjamin Lindner

This work reports a transfer function-based approach to characterizing the operation of single neuronal cells in terms of the instantaneous frequency of the input and output signals. We adopt the leaky integrate-and-fire model. The transfer…

Neurons and Cognition · Quantitative Biology 2019-10-23 Felipe L. Gewers , Luciano da F. Costa

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

Spiking Neural Networks (SNNs) are being explored to emulate the astounding capabilities of human brain that can learn and compute functions robustly and efficiently with noisy spiking activities. A variety of spiking neuron models have…

Neural and Evolutionary Computing · Computer Science 2020-06-17 Sayeed Shafayet Chowdhury , Chankyu Lee , Kaushik Roy

Nonlinear Noisy Leaky Integrate and Fire (NNLIF) models for neurons networks can be written as Fokker-Planck-Kolmogorov equations on the probability density of neurons, the main parameters in the model being the connectivity of the network…

Neurons and Cognition · Quantitative Biology 2010-10-25 María J. Cáceres , José A. Carrillo , Benoît Perthame

There is a wide range of mathematical models that describe populations of large numbers of neurons. In this article, we focus on nonlinear noisy leaky integrate-and-fire (NNLIF) models that describe neuronal activity at the level of the…

Analysis of PDEs · Mathematics 2024-12-12 María J. Cáceres , José A. Cañizo , Alejandro Ramos-Lora

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

Neurons and Cognition · Quantitative Biology 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

We consider a leaky integrate-and-fire neuron with deterministic subthreshold dynamics and a firing threshold that evolves as an Ornstein-Uhlenbeck process. The formulation of this minimal model is motivated by the experimentally observed…

Neurons and Cognition · Quantitative Biology 2015-05-12 Wilhelm Braun , Paul C. Matthews , Rüdiger Thul

Stochastic systems characterised by a random driving in a form of the general stable noise are considered. The particle experiences long rests due to the traps the density of which is position-dependent and obeys a power-law form attributed…

Statistical Mechanics · Physics 2016-07-06 Tomasz Srokowski

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

Neurons and Cognition · Quantitative Biology 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

Analytical expressions are put forward to investigate the forced spiking activity of abstract neuron models such as the driven leaky integrate-and-fire (LIF) model. The method is valid in a wide parameter regime beyond the restraining…

Neurons and Cognition · Quantitative Biology 2007-05-23 Michael Schindler , Peter Talkner , Peter Hänggi
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