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Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the…

Biological Physics · Physics 2018-12-12 John J. Williamson , Guillaume Salbreux

To design molecular spin qubits with enhanced quantum coherence, a control of the coupling between the local vibrations and the spin states is crucial, which could be realized in principle by engineering molecular structures via…

During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar filaments called microtubules. Establishing a stable overlap region is essential for maintenance of…

Biological Physics · Physics 2015-09-16 D. Johann , D. Goswami , K. Kruse

Proliferating cells properly divide into their daughter cells through a process that is mediated by kinetochores, protein-complexes that assemble at the centromere of each sister chromatid. Each kinetochore has to establish a tight bipolar…

Subcellular Processes · Quantitative Biology 2017-06-13 Bashar Ibrahim

Membrane tubes (spicules) arise in cells, or artificial membranes, in the nonlinear deformation regime due to, e.g. the growth of microtubules, actin filaments or sickle hemoglobin fibers towards a membrane. We calculate the axial force…

Soft Condensed Matter · Physics 2009-11-11 D. R. Daniels , M. S. Turner

Reaction force-aware control is essential for legged climbing robots to ensure a safer and more stable operation. This becomes particularly crucial when navigating steep terrain or operating in microgravity environments, where excessive…

Robotics · Computer Science 2024-09-23 Masazumi Imai , Kentaro Uno , Kazuya Yoshida

We report on a theoretical study of spin dynamics of an ensemble of spin-polarized electrons injected in a diffusive microchannel with linear Rashba and Dresselhaus spin-orbit coupling. We explore the dependence of the spin-precession and…

Mesoscale and Nanoscale Physics · Physics 2010-11-23 Liviu P. Zarbo , Jairo Sinova , Irena Knezevic , J. Wunderlich , T. Jungwirth

The cytoskeleton relies on diverse populations of motors, filaments, and binding proteins acting in concert to enable non-equilibrium processes ranging from mitosis to chemotaxis. Its versatile reconfigurability, programmed by interactions…

Vortices in a narrow superconducting strip with a square array of pinning sites are studied. The interactions of vortices with other vortices and with external sources (applied magnetic field and transport current) are calculated via a…

Superconductivity · Physics 2009-11-07 Clécio C. de Souza Silva , Leonardo R. E. Cabral , J. Albino Aguiar

Collective cell migration is crucial in many biological processes such as wound healing, tissue morphogenesis, and tumor progression. The leading front of a collective migrating epithelial cell layer often destabilizes into multicellular…

Biological Physics · Physics 2020-05-07 Yanjun Yang , Herbert Levine

Collective behaviors in cellular systems are regulated not only by biochemical signalling pathways but also by intercellular mechanical forces, whose quantification in contractile monolayers remains poorly understood. Here, by integrating…

Quantitative Methods · Quantitative Biology 2025-10-30 Yucheng Huo , Kexin Guo , Massimo Paradiso , K. Jimmy Hsia

Living cells adapt and respond actively to the mechanical properties of their environment. In addition to biochemical mechanotransduction, evidence exists for a myosin-dependent, purely mechanical sensitivity to the stiffness of the…

We derive the effective charge- and current-density operators for the strong-coupling limit of a single-band Mott insulator in the presence of spin-orbit coupling and show that the spin-orbit contribution to the effective charge density…

Strongly Correlated Electrons · Physics 2015-06-23 Shan Zhu , You-Quan Li , Cristian D. Batista

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

This paper describes an investigation into part of the mechanical mechanisms underlying the formation of mitotic spindle, the cellular machinery responsible for chromosomal separation during cell division. In normal eukaryotic cells,…

Subcellular Processes · Quantitative Biology 2019-05-29 Samira Masoudi , Cameron H. G. Wright , Jesse C. Gatlin , John. S. Oakey

We report the simultaneous characterization of time- and force-dependent mechanical properties of adherent cells in the physiologically relevant regime of large forces. We used magnetic tweezers to apply forces to magnetic beads bound to…

Biological Physics · Physics 2010-02-02 Philip Kollmannsberger , Claudia T. Mierke , Ben Fabry

We use numerical simulations and linear stability analysis to study the dynamics of an active liquid crystal film on a substrate in the regime where the passive system would be isotropic. Extensile activity builds up local orientational…

Soft Condensed Matter · Physics 2023-09-26 Fernando Caballero , Zhihong You , M. Cristina Marchetti

Cells exhibit qualitatively different behaviors on substrates with different rigidities. The fact that cells are more polarized on the stiffer substrate motivates us to construct a two-dimensional cell with the distribution of focal…

Biological Physics · Physics 2017-07-26 Guangyuan Yu , Jingchen Feng , Haoran Man , Herbert Levine

The spin-Hall effect describes the interconversion of charge currents and spin currents, enabling highly efficient manipulation of magnetization for spintronics. Symmetry conditions generally restrict polarizations of these spin currents to…

Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoeboid-like locomotion with protrusion of multiple pseudopods,…

Cell Behavior · Quantitative Biology 2009-03-16 Shin I. Nishimura , Masahiro Ueda , Masaki Sasai