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Identifying physiological and behavioral markers for mental health conditions is a longstanding challenge in psychiatry. Depression and suicidal ideation, in particular, lack objective biomarkers, with screening and diagnosis primarily…

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Computation and Language · Computer Science 2019-10-02 Bahman Mirheidari , Yilin Pan , Traci Walker , Markus Reuber , Annalena Venneri , Daniel Blackburn , Heidi Christensen

Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Harshinee Sriram , Cristina Conati , Thalia Field

Eye movements are intricate and dynamic events that contain a wealth of information about the subject and the stimuli. We propose an abstract representation of eye movements that preserve the important nuances in gaze behavior while being…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Louise Gillian C. Bautista , Prospero C. Naval

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and behavioral patterns. Eye movement data offers a non-invasive diagnostic tool for ASD detection, as it is inherently…

Machine Learning · Computer Science 2026-01-12 Zhanpei Huang , Taochen chen , Fangqing Gu , Yiqun Zhang

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Hongming Li , Yong Fan

With the rapid advancement in machine learning, the recognition and analysis of brain activity based on EEG and eye movement signals have attained a high level of sophistication. Utilizing deep learning models for learning EEG and eye…

Human-Computer Interaction · Computer Science 2024-07-16 Tian-Hua Li , Tian-Fang Ma , Dan Peng , Wei-Long Zheng , Bao-Liang Lu

Can human reading comprehension be assessed from eye movements in reading? In this work, we address this longstanding question using large-scale eyetracking data over textual materials that are geared towards behavioral analyses of reading…

Computation and Language · Computer Science 2025-02-18 Omer Shubi , Yoav Meiri , Cfir Avraham Hadar , Yevgeni Berzak

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is highly prevalent and requires clinical specialists to diagnose. It is known that an individual's viewing behavior, reflected in their eye movements, is…

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

Early diagnosis of Alzheimer's Disease (AD) is very important for following medical treatments, and eye movements under special visual stimuli may serve as a potential non-invasive biomarker for detecting cognitive abnormalities of AD…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Yu Liu , Wenlin Zhang , Shaochu Wang , Fangyu Zuo , Peiguang Jing , Yong Ji

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

We present a novel computational model employing hierarchical active inference to simulate reading and eye movements. The model characterizes linguistic processing as inference over a hierarchical generative model, facilitating predictions…

Neurons and Cognition · Quantitative Biology 2025-08-11 Francesco Donnarumma , Mirco Frosolone , Giovanni Pezzulo

Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising…

Machine Learning · Computer Science 2019-10-10 Charles K. Fisher , Aaron M. Smith , Jonathan R. Walsh , the Coalition Against Major Diseases

Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Taeho Jo , Kwangsik Nho , Andrew J. Saykin

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resource in the study of neurodegenerative diseases such as…

Machine Learning · Computer Science 2023-11-29 Gonzalo Uribarri , Simon Ekman von Huth , Josefine Waldthaler , Per Svenningsson , Erik Fransén

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh
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