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When a founder cell and its progeny divide with incomplete cytokinesis, a network forms in which each intercellular bridge corresponds to a past mitotic event. Networks built in this manner are required for gamete production in many…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Matthew Smart , Stanislav Shvartsman , Hayden Nunley

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…

Machine Learning · Statistics 2026-01-09 James Rice

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…

Quantitative Methods · Quantitative Biology 2019-07-23 Helen M Byrne , Heather A Harrington , Ruth Muschel , Gesine Reinert , Bernadette J Stolz , Ulrike Tillmann

The network topology can be described by the number of nodes and the interconnections among them. The degree of a node in a network is the number of connections it has to other nodes and the degree distribution is the probability…

Physics and Society · Physics 2014-09-19 Bin Zhou , Bing-Hong Wang , He Zhe

Numerous theories of learning propose to prevent the gradient from exponential growth with depth or time, to stabilize and improve training. Typically, these analyses are conducted on feed-forward fully-connected neural networks or simple…

Machine Learning · Computer Science 2024-01-08 Luca Herranz-Celotti , Jean Rouat

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

Statistical Mechanics · Physics 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

Our work is motivated by a desire to study the theoretical underpinning for the convergence of stochastic gradient type algorithms widely used for non-convex learning tasks such as training of neural networks. The key insight, already…

Probability · Mathematics 2020-12-15 Kaitong Hu , Zhenjie Ren , David Siska , Lukasz Szpruch

The question of how and why the phenomenon of mode connectivity occurs in training deep neural networks has gained remarkable attention in the research community. From a theoretical perspective, two possible explanations have been proposed:…

Machine Learning · Computer Science 2021-10-22 Quynh Nguyen , Pierre Brechet , Marco Mondelli

Liquid-liquid phase separation is an important mechanism for compartmentalizing the cell's cytoplasm, allowing the dynamic organization of the components necessary for survival. However, it is not clear how phase separation is affected by…

Soft Condensed Matter · Physics 2022-01-31 Estefania Vidal-Henriquez , David Zwicker

This chapter discusses the interplay between structure and dynamics in complex networks. Given a particular network with an endowed dynamics, our goal is to find partitions aligned with the dynamical process acting on top of the network. We…

Social and Information Networks · Computer Science 2020-05-08 Michael T. Schaub , Jean-Charles Delvenne , Renaud Lambiotte , Mauricio Barahona

We study the dynamics of the processes in the small-world networks with a power-law degree distribution where every node is considered to be in one of the two available statuses. We present an algorithm for generation of such network and…

Statistical Mechanics · Physics 2019-07-19 Bahruz Gadjiev , Tatiana Progulova

Many real-world phenomena can be modelled as dynamical processes on networks, a prominent example being the spread of infectious diseases such as COVID-19. Mean-field approximations are a widely used tool to analyse such dynamical processes…

Probability · Mathematics 2025-08-25 Jonathan A. Ward , Gábor Timár , Péter L. Simon

Different types of interactions coexist and coevolve to shape the structure and function of a multiplex network. We propose here a general class of growth models in which the various layers of a multiplex network coevolve through a set of…

Physics and Society · Physics 2014-10-15 Vincenzo Nicosia , Ginestra Bianconi , Vito Latora , Marc Barthelemy

We introduce a minimalistic model based on dynamic node deletion and node duplication with heterodimerisation. The model is intended to capture the essential features of the evolution of protein interaction networks. We derive an exact…

Biological Physics · Physics 2009-11-13 Nadia Farid , Kim Christensen

To explain the differentiation of stem cells in terms of dynamical systems theory, models of interacting cells with intracellular protein expression dynamics are analyzed and simulated. Simulations were carried out for all possible protein…

Cell Behavior · Quantitative Biology 2015-06-15 Yusuke Goto , Kunihiko Kaneko

The mean-field limit of a Markovian model describing the interaction of several classes of permanent connections in a network is analyzed. Each of the connections has a self-adaptive behavior in that its transmission rate along its route…

Probability · Mathematics 2009-12-15 Carl Graham , Philippe Robert

The study of Deep Network (DN) training dynamics has largely focused on the evolution of the loss function, evaluated on or around train and test set data points. In fact, many DN phenomenon were first introduced in literature with that…

Machine Learning · Computer Science 2023-10-23 Ahmed Imtiaz Humayun , Randall Balestriero , Richard Baraniuk

Mitochondrial DNA (mtDNA) mutations cause severe congenital diseases but may also be associated with healthy aging. MtDNA is stochastically replicated and degraded, and exists within organelles which undergo dynamic fusion and fission. The…

Subcellular Processes · Quantitative Biology 2019-07-04 Juvid Aryaman , Charlotte Bowles , Nick S. Jones , Iain G. Johnston

Geometric constraints impact the formation of a broad range of spatial networks, from amino acid chains folding to proteins structures to rearranging particle aggregates. How the network of interactions dynamically self-organizes in such…

Molecular Networks · Quantitative Biology 2016-10-19 Nora Molkenthin , Marc Timme

This paper addresses the problem of online learning in a dynamic setting. We consider a social network in which each individual observes a private signal about the underlying state of the world and communicates with her neighbors at each…

Optimization and Control · Mathematics 2013-10-02 Shahin Shahrampour , Alexander Rakhlin , Ali Jadbabaie