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Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

Discrete Mathematics · Computer Science 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

A hybrid framework combining the branch and bound method with multiobjective evolutionary algorithms is proposed for nonconvex multiobjective optimization. The hybridization exploits the complementary character of the two optimization…

Optimization and Control · Mathematics 2022-12-12 Wei-tian Wu , Xin-min Yang

We propose a hierarchical architecture for efficiently computing high-quality solutions to structured mixed-integer programs (MIPs). To reduce computational effort, our approach decouples the original problem into a higher level problem and…

Optimization and Control · Mathematics 2025-12-04 Stefan Clarke , Bartolomeo Stellato

Hypergraph matching has recently become a popular approach for solving correspondence problems in computer vision as it allows to integrate higher-order geometric information. Hypergraph matching can be formulated as a third-order…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Quynh Nguyen , Francesco Tudisco , Antoine Gautier , Matthias Hein

In this article, we investigate different parsimony-based approaches towards finding recombination breakpoints in a multiple sequence alignment. This recombination detection task is crucial in order to avoid errors in evolutionary analyses…

Populations and Evolution · Quantitative Biology 2019-10-25 Mark Jones , Philippe Gambette , Leo van Iersel , Remie Janssen , Steven Kelk , Fabio Pardi , Celine Scornavacca

Given a text $T$ and a pattern $P$, the order-preserving matching problem is to find all substrings in $T$ which have the same relative orders as $P$. Order-preserving matching has been an active research area since it was introduced by…

Data Structures and Algorithms · Computer Science 2015-06-18 Myoungji Han , Munseong Kang , Sukhyeun Cho , Geonmo Gu , Jeong Seop Sim , Kunsoo Park

Discrete optimization is a central problem in mathematical optimization with a broad range of applications, among which binary optimization and sparse optimization are two common ones. However, these problems are NP-hard and thus difficult…

Optimization and Control · Mathematics 2018-11-26 Ganzhao Yuan , Li Shen , Wei-Shi Zheng

A core feature of evolutionary algorithms is their mutation operator. Recently, much attention has been devoted to the study of mutation operators with dynamic and non-uniform mutation rates. Following up on this line of work, we propose a…

Data Structures and Algorithms · Computer Science 2018-11-22 Tobias Friedrich , Andreas Göbel , Francesco Quinzan , Markus Wagner

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

Populations and Evolution · Quantitative Biology 2018-08-24 David A. Morrison

We consider a simple setting in neuroevolution where an evolutionary algorithm optimizes the weights and activation functions of a simple artificial neural network. We then define simple example functions to be learned by the network and…

Neural and Evolutionary Computing · Computer Science 2023-10-17 Paul Fischer , Emil Lundt Larsen , Carsten Witt

Heuristic algorithms have shown a good ability to solve a variety of optimization problems. Stockpile blending problem as an important component of the mine scheduling problem is an optimization problem with continuous search space…

Neural and Evolutionary Computing · Computer Science 2021-02-11 Yue Xie , Aneta Neumann , Frank Neumann

Large-scale sparse multi-objective optimization problems (LSMOPs) are prevalent in real-world applications, where optimal solutions typically contain only a few nonzero variables, such as in adversarial attacks, critical node detection, and…

Neural and Evolutionary Computing · Computer Science 2026-03-13 Shuai Shao , Yuhao Sun , Xing Chen , Ye Tian , Guan Wang , Jin Li

Most algorithms for computing persistent homology do so by tracking cycles that represent homology classes. There are many choices of such cycles, and specific choices have found different uses in applications. Although it is known that…

Algebraic Topology · Mathematics 2025-04-01 Dmitriy Morozov , Primoz Skraba

Population-based evolutionary algorithms have great potential to handle multiobjective optimisation problems. However, these algorithms depends largely on problem characteristics, and there is a need to improve their performance for a wider…

Neural and Evolutionary Computing · Computer Science 2019-10-17 Shouyong Jiang , Hongru Li , Jinglei Guo , Mingjun Zhong , Shengxiang Yang , Marcus Kaiser , Natalio Krasnogor

The Symbolic Regression (SR) problem, where the goal is to find a regression function that does not have a pre-specified form but is any function that can be composed of a list of operators, is a hard problem in machine learning, both…

Machine Learning · Computer Science 2020-06-15 Vernon Austel , Cristina Cornelio , Sanjeeb Dash , Joao Goncalves , Lior Horesh , Tyler Josephson , Nimrod Megiddo

Genome assembly using high throughput data with short reads, arguably, remains an unresolvable task in repetitive genomes, since when the length of a repeat exceeds the read length, it becomes difficult to unambiguously connect the flanking…

Quantitative Methods · Quantitative Biology 2013-07-31 Viraj Deshpande , Eric DK Fung , Son Pham , Vineet Bafna

Best match graphs (BMGs) are a class of colored digraphs that naturally appear in mathematical phylogenetics and can be approximated with the help of similarity measures between gene sequences, albeit not without errors. The corresponding…

Combinatorics · Mathematics 2021-03-15 David Schaller , Manuela Geiß , Marc Hellmuth , Peter F. Stadler

In this paper we consider the problem of computing an mRNA sequence of maximal similarity for a given mRNA of secondary structure constraints, introduced by Backofen et al. in [BNS02] denoted as the MRSO problem. The problem is known to be…

Data Structures and Algorithms · Computer Science 2007-05-23 Frank Gurski

In this paper, first we give a sequential linear-time algorithm for the longest path problem in meshes. This algorithm can be considered as an improvement of [13]. Then based on this sequential algorithm, we present a constant-time parallel…

Data Structures and Algorithms · Computer Science 2012-01-24 Fatemeh Keshavarz-Kohjerdi , Alireza Bagheri

Deep Optimisation (DO) combines evolutionary search with Deep Neural Networks (DNNs) in a novel way - not for optimising a learning algorithm, but for finding a solution to an optimisation problem. Deep learning has been successfully…

Machine Learning · Computer Science 2018-11-05 J. R. Caldwell , R. A. Watson , C. Thies , J. D. Knowles
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