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Recurrent Neural Networks (RNNs) have been proven to be effective in modeling sequential data and they have been applied to boost a variety of tasks such as document classification, speech recognition and machine translation. Most of…

Computation and Language · Computer Science 2018-08-21 Zhiwei Wang , Yao Ma , Dawei Yin , Jiliang Tang

Deep-learning models such as Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) have been successfully used for process-mining tasks. They have achieved better performance for different predictive tasks than traditional…

Machine Learning · Computer Science 2021-05-04 Ishwar Venugopal , Jessica Töllich , Michael Fairbank , Ansgar Scherp

High throughput sequencing techniques have highly impactedon modern biology, widening the gap between sequenced andannotated data. Automatic annotation tools are thereforeof the foremost importance to guide biologists' experiments. However,…

Machine Learning · Statistics 2016-10-02 Luca Masera

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

Biomolecules · Quantitative Biology 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

Machine learning and the use of neural networks has increased precipitously over the past few years primarily due to the ever-increasing accessibility to data and the growth of computation power. It has become increasingly easy to harness…

Machine Learning · Computer Science 2020-08-05 Aaron Hein , Casey Cole , Homayoun Valafar

In the recent publication (arxiv:2007.08063v2 [cs.LG]) a fast prediction algorithm for a single recurrent network (RN) was suggested. In this manuscript we generalize this approach to a chain of RNs and show that it can be implemented in…

Dynamical Systems · Mathematics 2020-10-06 Boris Rubinstein

The random neural network (RNN) is a mathematical model for an "integrate and fire" spiking network that closely resembles the stochastic behaviour of neurons in mammalian brains. Since its proposal in 1989, there have been numerous…

Neural and Evolutionary Computing · Computer Science 2018-10-23 Yonghua Yin

We present an architecture of a recurrent neural network (RNN) with a fully-connected deep neural network (DNN) as its feature extractor. The RNN is equipped with both causal temporal prediction and non-causal look-ahead, via…

Machine Learning · Computer Science 2014-03-07 Jianshu Chen , Li Deng

Recurrent Neural Networks (RNN) are a type of statistical model designed to handle sequential data. The model reads a sequence one symbol at a time. Each symbol is processed based on information collected from the previous symbols. With…

Machine Learning · Statistics 2019-02-18 Jared Ostmeyer , Lindsay Cowell

An increasing number of emerging applications in data science and engineering are based on multidimensional and structurally rich data. The irregularities, however, of high-dimensional data often compromise the effectiveness of standard…

Processing sequential data of variable length is a major challenge in a wide range of applications, such as speech recognition, language modeling, generative image modeling and machine translation. Here, we address this challenge by…

Neural and Evolutionary Computing · Computer Science 2017-06-13 Asier Mujika , Florian Meier , Angelika Steger

Real-time lightweight time series anomaly detection has become increasingly crucial in cybersecurity and many other domains. Its ability to adapt to unforeseen pattern changes and swiftly identify anomalies enables prompt responses and…

Machine Learning · Computer Science 2024-07-29 Ming-Chang Lee , Jia-Chun Lin , Sokratis Katsikas

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Recurrent neural networks (RNNs) are capable of learning features and long term dependencies from sequential and time-series data. The RNNs have a stack of non-linear units where at least one connection between units forms a directed cycle.…

Neural and Evolutionary Computing · Computer Science 2018-02-26 Hojjat Salehinejad , Sharan Sankar , Joseph Barfett , Errol Colak , Shahrokh Valaee

Recurrent Neural Networks (RNNs) with Long Short-Term Memory units (LSTM) are widely used because they are expressive and are easy to train. Our interest lies in empirically evaluating the expressiveness and the learnability of LSTMs in the…

Neural and Evolutionary Computing · Computer Science 2015-11-24 Wojciech Zaremba , Ilya Sutskever

After AlphaFold won the Nobel Prize, protein prediction with deep learning once again became a hot topic. We comprehensively explore advanced deep learning methods applied to protein structure prediction and design. It begins by examining…

Protein secondary structure prediction is an important problem in bioinformatics. Inspired by the recent successes of deep neural networks, in this paper, we propose an end-to-end deep network that predicts protein secondary structures from…

Biomolecules · Quantitative Biology 2016-04-27 Zhen Li , Yizhou Yu

Many machine learning tasks can be expressed as the transformation---or \emph{transduction}---of input sequences into output sequences: speech recognition, machine translation, protein secondary structure prediction and text-to-speech to…

Neural and Evolutionary Computing · Computer Science 2012-11-16 Alex Graves

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

Computational Engineering, Finance, and Science · Computer Science 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li
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