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With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

In this paper, the decades-old clustering method k-means is revisited. The original distortion minimization model of k-means is addressed by a pure stochastic minimization procedure. In each step of the iteration, one sample is tentatively…

Machine Learning · Computer Science 2020-05-20 Wan-Lei Zhao , Run-Qing Chen , Hui Ye , Chong-Wah Ngo

We propose a simple yet effective multiple kernel clustering algorithm, termed simple multiple kernel k-means (SimpleMKKM). It extends the widely used supervised kernel alignment criterion to multi-kernel clustering. Our criterion is given…

Machine Learning · Computer Science 2020-05-13 Xinwang Liu , En Zhu , Jiyuan Liu , Timothy Hospedales , Yang Wang , Meng Wang

In this work, we aim to solve a practical use-case of unsupervised clustering which has applications in predictive maintenance in the energy operations sector using quantum computers. Using only cloud access to quantum computers, we…

Quantum Physics · Physics 2022-09-13 Stephen DiAdamo , Corey O'Meara , Giorgio Cortiana , Juan Bernabé-Moreno

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine…

Machine Learning · Statistics 2019-08-13 Hrayr Harutyunyan , Hrant Khachatrian , David C. Kale , Greg Ver Steeg , Aram Galstyan

Scientific research frequently involves the use of computational tools and methods. Providing thorough documentation, open-source code, and data -- the creation of reproducible computational research -- helps others understand a…

Digital Libraries · Computer Science 2022-09-14 Tim von Hahn , Chris K. Mechefske

k-means is one of the most influential and utilized machine learning algorithms. Its computation limits the performance and scalability of many statistical analysis and machine learning tasks. We rethink and optimize k-means in terms of…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-27 Disa Mhembere , Da Zheng , Carey E. Priebe , Joshua T. Vogelstein , Randal Burns

We present an efficient low-rank updating algorithm for updating the trial wavefunctions used in Quantum Monte Carlo (QMC) simulations. The algorithm is based on low-rank updating of the Slater determinants. In particular, the computational…

Materials Science · Physics 2009-06-25 Phani K. V. V. Nukala , P. R. C. Kent

We use the benefits and components of classical computers every day. However, there are many types of problems which, as they grow in size, their computational complexity grows larger than classical computers will ever be able to solve.…

This paper provides new algorithms for distributed clustering for two popular center-based objectives, k-median and k-means. These algorithms have provable guarantees and improve communication complexity over existing approaches. Following…

Machine Learning · Computer Science 2020-01-28 Maria Florina Balcan , Steven Ehrlich , Yingyu Liang

Population Monte Carlo (PMC) sampling methods are powerful tools for approximating distributions of static unknowns given a set of observations. These methods are iterative in nature: at each step they generate samples from a proposal…

Computation · Statistics 2022-01-17 Víctor Elvira , Luca Martino , David Luengo , Mónica F. Bugallo

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Real-life engineering optimization problems need Multiobjective Optimization (MOO) tools. These problems are highly nonlinear. As the process of Multiple Criteria Decision-Making (MCDM) is much expanded most MOO problems in different…

Software Engineering · Computer Science 2010-04-20 A. Mosavi

We show that multiplication can be done in polynomial time on a three counter machine that receives its input as the contents of two counters. The technique is generalized to functions of two variables computable by deterministic Turing…

Computational Complexity · Computer Science 2015-01-12 Holger Petersen

Recently, using automatic configuration tuning to improve the performance of modern database management systems (DBMSs) has attracted increasing interest from the database community. This is embodied with a number of systems featuring…

Databases · Computer Science 2022-03-15 Xinyi Zhang , Zhuo Chang , Yang Li , Hong Wu , Jian Tan , Feifei Li , Bin Cui

We present a new algorithm for reducing an arbitrary unitary matrix into a sequence of elementary operations (operations such as controlled-nots and qubit rotations). Such a sequence of operations can be used to manipulate an array of…

Quantum Physics · Physics 2007-05-23 Robert R. Tucci

Characterizing quantum systems through experimental data is critical to applications as diverse as metrology and quantum computing. Analyzing this experimental data in a robust and reproducible manner is made challenging, however, by the…

Skyline is widely used in reality to solve multi-criteria problems, such as environmental monitoring and business decision-making. When a data is not worse than another data on all criteria and is better than another data at least one…

Databases · Computer Science 2021-11-17 Chuan-Chi Lai , Hsuan-Yu Lin , Chuan-Ming Liu

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

We propose Kernel Predictive Control (KPC), a learning-based predictive control strategy that enjoys deterministic guarantees of safety. Noise-corrupted samples of the unknown system dynamics are used to learn several models through the…

Systems and Control · Electrical Eng. & Systems 2020-11-24 Emilio T. Maddalena , Paul Scharnhorst , Yuning Jiang , Colin N. Jones